Biocompatibility of Fe3O4/DNR magnetic nanoparticles in the treatment of hematologic malignancies

International Journal of Nanomedicine

Volumn 5, Issue 1, 2010, Pages 1079-1084

  Wu, Weiwei ^a   Chen, Baoan ^a   Cheng, Jian ^a   Wang, Jun ^a   Xu, Wenlin ^b   Liu, Lijie ^a   Xia, Guohua ^a   Wei, Hulai ^c   Wang, Xuemei ^a   Yang, Mingming ^a   Yang, Liya ^a   Zhang, Yi ^a   Xu, Chuanlu ^a   Li, Jieyong ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b First People's Hospital of Zhenjiang   (China)

^c LANZHOU UNIVERSITY   (China)

Author keywords

Biocompatibility; Daunorubicin; Fe3O4; Hematologic malignancies; Magnetic nanoparticles; Therapy

Indexed keywords

ALANINE AMINOTRANSFERASE; CYCLOPHOSPHAMIDE; DAUNORUBICIN; DAUNORUBICIN MAGNETIC IRON OXIDE NANOPARTICLE; IRON OXIDE; NANOPARTICLE; NITROGEN; UNCLASSIFIED DRUG; UREA; BIOMATERIAL; MAGNETITE NANOPARTICLE;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOCOMPATIBILITY; BLOOD TOXICITY; BODY WEIGHT; CONTROLLED STUDY; CONVULSION; CREATININE CLEARANCE; DRUG SYNTHESIS; GAIT DISORDER; GENOTOXICITY; HEMATOLOGIC MALIGNANCY; HEMOLYSIS; LD 50; LIVER TOXICITY; MICRONUCLEUS TEST; MOUSE; NEPHROTOXICITY; NONHUMAN; PARALYSIS; RABBIT; RESPIRATION DEPRESSION; TOXICITY TESTING; UREA NITROGEN BLOOD LEVEL; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; BLOOD DISEASE; CHEMISTRY; DRUG EFFECT; FEMALE; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; METABOLISM;

MUS;

ANALYSIS OF VARIANCE; ANIMALS; BIOCOMPATIBLE MATERIALS; BODY WEIGHT; DAUNORUBICIN; FEMALE; HEMATOLOGIC NEOPLASMS; HEMOLYSIS; HUMANS; INJECTIONS, INTRAPERITONEAL; LETHAL DOSE 50; MAGNETITE NANOPARTICLES; MALE; MICE; MICRONUCLEUS TESTS;

EID: 79954549813     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S15660     Document Type: Article

References (26)

1. Alexiou C, Arnold W, Klein RJ, et al. Locoregional cancer treatment with magnetic drug targeting. Cancer Res. 2000;60:6641-6648.
2. Alexiou C, Jurgons R, Schmid RJ, et al. Magnetic drug targeting - biodistribution of the magnetic carrier and the chemotherapeutic agent mitoxantrone after locoregional cancer treatment. J Drug Target. 2003; 11:139-149.
3. Ito A, Tanaka K, Kondo K, et al. Tumor regression by combined immunotherapy and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma. Cancer Sci. 2003;94: 308-313.
4. Artemov D. Molecular magnetic resonance imaging with targeted contrast agents. J Cell Biochem. 2003;90:518-524.
5. Cheng J, Wu WW, Chen BA, et al. Effect of magnetic nanoparticles of Fe3O4 and 5-bromotetrandrine on reversal of multidrug resistance in K562/A02 leukemic cells. Int J Nanomedicine. 2009; 4:209-216.
6. 4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells. Int J Nanomedicine. 2009; 4: 65-71.
7. 4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice. Int J Nanomedicine. 2009; 4: 73-78.
8. Mohamed F, Marchettini P, Stuart OA, Utano M, Sugarbaker PH. Thermal enhancement of new chemotherapeutic agents at moderate hyperthermia. Ann Surg Oncol. 2003; 10: 463-468.
9. Jain TK, Reddy MK, Morales MA, Leslie-Pelecky DL, Labhasetwar V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol Pharm. 2008; 5: 316-327.
10. Ma M, Zhu Y, Zhang Y, et al. Preparation of magnetic nanoparticles and interaction with cancer cell. J Southeast Univ (Natural Science Edition). 2003; 33: 205-207.
11. Cui S, Shen XD, Lin BL, et al. Synthesis and characterization of magnetic adriamycin HAS nanoparticle. Chin J Biomed Eng. 2006; 25:114-116.
12. Martino-Roth MG, Viegas J, Roth DM. Occupational genotoxicity risk evaluation through the Comet assay and the micronucleus test. Genet Mol Res. 2003; 2: 410-417.
13. Wu D, Zhang GD, Sun LW, et al. Toxicological study on phenol and o-methyphenol - two kinds of environmental endocrine disrupting chemical. J Nanjing Univ (Natural Sciences). 2001; 37: 719-723.
14. Wang H, Wu X, Zhang S, et al. Experimental study on the biocompatibility and security of a rhBMP-2 loaded amorphous calcium phosphate delayed release nano-sized material. Orthop J China. 2008; 16:1720-1723.
15. Cheng FY, Su CH, Yang YS, et al. Characterization of aqueous dispersions of Fe3O4 nanoparticles and their biomedical applications. Biomaterials. 2005;26:729-738.
16. Xi TF. Biological evaluation of biology based on medical devices. China Medical Device Information. 1999;5:9-14.
17. Sun J, Gu GZ, Qian YF. Influence of different contact ways and extracting conditions on the hemolytic effect of biomaterials. J Biomed Eng. 2003;20:8-10.
18. Zhang WY, Shen Y, Li N, Chen JH, Jia AQ. Evaluation of biocompatibility of fiber-reinforced dental composites. Med J Chin PLA. 2004;29:345-347.
19. Liu WW, Wang T, Zhan DS. Haemolysis test for evaluating the biocompatibility of SiC implant materials. CRTER. 2008;12: 1873-1875.
20. Domke J, Dannohl S, Parak WJ, et al. Substrate dependent differences in morphology and elasticity of living osteoblasts investigated by atomic force microscopy. Colloids Surf B. 2000;19:367-379.
21. Zhao XW, Lin JH, Wang ZR. Study on biocompatibility and security of homemade calcium phosphate cement. Journal of Fujian Medical University. 2002;36:388-392.
22. Bezwoda WR. High-dose chemotherapy with hematopoietic rescue in breast cancer: From theory to practice. Cancer Chemother Pharmacol. 1997;40:S79-S87.
23. Owens DE, Peppas NA. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int J Pharm. 2006; 307:93-102.
24. Okon E, Pouliquen D, Okon P, et al. Biodegradation of magnetite dextran nanoparticles in the rat. A histologic and biophysical study. Lab Invest. 1994; 71:895-903.
25. Chouly C, Pouliquen D, Lucet I, Jeune JJ, Jallet P. Development of superparamagnetic nanoparticles for MRI: Effect of particle size, charge and surface nature on biodistribution. J Microencapsul. 1996; 13:245-255.
26. Briley-Saebo K, Bjomerud A, Grant D, Ahlstrom H, Berg T, Kindberg GM. Hepatic cellular distribution and degradation of irom oxide nanoparticles following single intravenous injection in rats: Implications for magnetic resonance imaging. Cell Tissue Res. 2004; 316:315-323.