High-throughput liquid chromatography - Tandem mass spectrometric method for simultaneous quantification of carvedilol and its metabolite 4- hydroxyphenyl carvedilol in human plasma and its application to bioequivalence study

Journal of Chemical and Pharmaceutical Research

Volumn 3, Issue 2, 2011, Pages 341-353

  Chandiran Sarath, I ^a   Jayaveera, K N ^b   Raghunadha Reddy, R ^c  

^a Gokula Krishna College of Pharmacy   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^c Clinical Research and Biosciences (I) Pvt Ltd   (India)

Author keywords

4 Hydroxyphenyl Carvedilol; Carvedilol; High throughput liquid Chromatography; Human plasma; MS MS; Validation

Indexed keywords

4 HYDROXYPHENYL CARVEDILOL; CARVEDILOL; DRUG METABOLITE; PROPRANOLOL; UNCLASSIFIED DRUG;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; AUTOANALYSIS; BIOEQUIVALENCE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG DOSAGE FORM COMPARISON; DRUG HALF LIFE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; ONLINE SYSTEM; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION PROCESS;

EID: 79954545077     PISSN: None     EISSN: 09757384     Source Type: Journal    
DOI: None     Document Type: Article

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