메뉴 건너뛰기




Volumn 300, Issue 3, 2011, Pages

Asarm peptides: PHEX-dependent and -independent regulation of serum phosphate

Author keywords

1; 25 dihydroxy vitamin D3; Dentin matrix protein 1; Fibroblast growth factor 23; Matrix extracellular phosphoglycoprotein; Mineralization; Osteomalacia; SIBLING proteins; X linked hypophosphatemic rickets

Indexed keywords

COLECALCIFEROL; COTRANSPORTER; FIBROBLAST GROWTH FACTOR 23; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; PARATHYROID HORMONE; PEPTIDE DERIVATIVE; PHOSPHATE; PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; PHOSPHORUS; PROTEIN ASARM; PROTEIN NPT2A; UNCLASSIFIED DRUG;

EID: 79954540547     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00304.2010     Document Type: Article
Times cited : (49)

References (66)
  • 1
    • 77953229051 scopus 로고    scopus 로고
    • Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage
    • Addison W, Masica D, Gray J, McKee MD. Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage. J Bone Miner Res 25: 695-705, 2009.
    • (2009) J Bone Miner Res , vol.25 , pp. 695-705
    • Addison, W.1    Masica, D.2    Gray, J.3    McKee, M.D.4
  • 2
    • 52949134423 scopus 로고    scopus 로고
    • MEPE-ASARM peptides control extracellular matrix mineralization by binding to hy-droxyapatite-an inhibition regulated by PHEX cleavage of ASARM
    • Addison W, Nakano Y, Loisel T, Crine P, McKee M. MEPE-ASARM peptides control extracellular matrix mineralization by binding to hy-droxyapatite-an inhibition regulated by PHEX cleavage of ASARM. J Bone Miner Res 23: 1638-1649, 2008.
    • (2008) J Bone Miner Res , vol.23 , pp. 1638-1649
    • Addison, W.1    Nakano, Y.2    Loisel, T.3    Crine, P.4    McKee, M.5
  • 3
    • 0035874943 scopus 로고    scopus 로고
    • Mepe, the gene encoding a tumor-secreted protein in oncogenic hypophosphatemic osteo-malacia, is expressed in bone
    • Argiro L, Desbarats M, Glorieux FH, Ecarot B. Mepe, the gene encoding a tumor-secreted protein in oncogenic hypophosphatemic osteo-malacia, is expressed in bone. Genomics 74: 342-351, 2001.
    • (2001) Genomics , vol.74 , pp. 342-351
    • Argiro, L.1    Desbarats, M.2    Glorieux, F.H.3    Ecarot, B.4
  • 4
    • 12244263475 scopus 로고    scopus 로고
    • Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression
    • Bai X, Miao D, Panda D, Grady S, McKee MD, Goltzman D, Karaplis AC. Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression. Mol Endocrinol 16: 2913-2925, 2002.
    • (2002) Mol Endocrinol , vol.16 , pp. 2913-2925
    • Bai, X.1    Miao, D.2    Panda, D.3    Grady, S.4    McKee, M.D.5    Goltzman, D.6    Karaplis, A.C.7
  • 5
    • 39749187284 scopus 로고    scopus 로고
    • Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): Multifunctional proteins in cancer
    • Bellahcene A, Castronovo V, Ogbureke KU, Fisher LW, Fedarko NS. Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer. Nat Rev Cancer 8: 212-226, 2008.
    • (2008) Nat Rev Cancer , vol.8 , pp. 212-226
    • Bellahcene, A.1    Castronovo, V.2    Ogbureke, K.U.3    Fisher, L.W.4    Fedarko, N.S.5
  • 9
    • 11244270453 scopus 로고    scopus 로고
    • Serum MEPE-ASARM peptides are elevated in X-linked rickets (HYP): Implications for phosphaturia and rickets
    • Bresler D, Bruder J, Mohnike KL, Fraser D, Rowe PSN. Serum MEPE-ASARM peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets. J Endocrinol 183: R1-R9, 2004.
    • (2004) J Endocrinol , vol.183
    • Bresler, D.1    Bruder, J.2    Mohnike, K.L.3    Fraser, D.4    Rowe, P.S.N.5
  • 10
    • 0038343128 scopus 로고    scopus 로고
    • Human recombinant endopeptidase PHEX has a strict S1= specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phos-phoglycoprotein
    • Campos M, Couture C, Hirata IY, Juliano MA, Loisel TP, Crine P, Juliano L, Boileau G, Carmona AK. Human recombinant endopeptidase PHEX has a strict S1= specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phos-phoglycoprotein. Biochem J 373: 271-279, 2003.
    • (2003) Biochem J , vol.373 , pp. 271-279
    • Campos, M.1    Couture, C.2    Hirata, I.Y.3    Juliano, M.A.4    Loisel, T.P.5    Crine, P.6    Juliano, L.7    Boileau, G.8    Carmona, A.K.9
  • 12
    • 69949178239 scopus 로고    scopus 로고
    • Modulation of calcium oxalate dihydrate growth by selective crystal-face binding of phosphorylated osteopontin and polyaspartate peptide showing occlusion by sectoral (compositional) zoning
    • Chien YC, Masica DL, Gray JJ, Nguyen S, Vali H, McKee MD. Modulation of calcium oxalate dihydrate growth by selective crystal-face binding of phosphorylated osteopontin and polyaspartate peptide showing occlusion by sectoral (compositional) zoning. J Biol Chem 284: 23491-23501, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 23491-23501
    • Chien, Y.C.1    Masica, D.L.2    Gray, J.J.3    Nguyen, S.4    Vali, H.5    McKee, M.D.6
  • 13
    • 69249117464 scopus 로고    scopus 로고
    • Matrix extracellular phos-phoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator
    • David V, Martin A, Hedge AM, Rowe PS. Matrix extracellular phos-phoglycoprotein (MEPE) is a new bone renal hormone and vascularization modulator. Endocrinology 150: 4012-4023, 2009.
    • (2009) Endocrinology , vol.150 , pp. 4012-4023
    • David, V.1    Martin, A.2    Hedge, A.M.3    Rowe, P.S.4
  • 14
    • 44449138422 scopus 로고    scopus 로고
    • Matrix extracellular phosphoglycoprotein causes phosphaturia in rats by inhibiting tubular phosphate reabsorption
    • Dobbie H, Unwin RJ, Faria NJ, Shirley DG. Matrix extracellular phosphoglycoprotein causes phosphaturia in rats by inhibiting tubular phosphate reabsorption. Nephrol Dial Transplant 23: 730-733, 2008.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 730-733
    • Dobbie, H.1    Unwin, R.J.2    Faria, N.J.3    Shirley, D.G.4
  • 15
    • 0141576605 scopus 로고    scopus 로고
    • Hypophosphatemic rickets
    • Drezner MK. Hypophosphatemic rickets. Endocr Dev 6: 126-155, 2003.
    • (2003) Endocr Dev , vol.6 , pp. 126-155
    • Drezner, M.K.1
  • 16
    • 0036838193 scopus 로고    scopus 로고
    • Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport
    • Dubois SG, Ruchon AF, Delalandre A, Boileau G, Lajeunesse D. Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport. Am J Physiol Cell Physiol 283: C1414-C1421, 2002.
    • Am J Physiol Cell Physiol , vol.283
    • Dubois, S.G.1    Ruchon, A.F.2    Delalandre, A.3    Boileau, G.4    Lajeunesse, D.5
  • 17
    • 3042703295 scopus 로고    scopus 로고
    • Three small integrin-binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases
    • Fedarko NS, Jain A, Karadag A, Fisher LW. Three small integrin-binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases. FASEB J 18: 734-736, 2004.
    • (2004) FASEB J , vol.18 , pp. 734-736
    • Fedarko, N.S.1    Jain, A.2    Karadag, A.3    Fisher, L.W.4
  • 21
    • 78649570143 scopus 로고    scopus 로고
    • Effects of impaired functional domains of osteopontin on renal crystal formation: Analyses of OPN transgenic and OPN knockout mice
    • Hamamoto S, Nomura S, Yasui T, Okada A, Hirose M, Shimizu H, Itoh Y, Tozawa K, Kohri K. Effects of impaired functional domains of osteopontin on renal crystal formation: analyses of OPN transgenic and OPN knockout mice. J Bone Miner Res 25: 2436-2447, 2010.
    • (2010) J Bone Miner Res , vol.25 , pp. 2436-2447
    • Hamamoto, S.1    Nomura, S.2    Yasui, T.3    Okada, A.4    Hirose, M.5    Shimizu, H.6    Itoh, Y.7    Tozawa, K.8    Kohri, K.9
  • 23
    • 0034963551 scopus 로고    scopus 로고
    • Phosphorylated osteopontin peptides suppress crystallization by inhibiting the growth of calcium oxalate crystals
    • Hoyer JR, Asplin JR, Otvos L. Phosphorylated osteopontin peptides suppress crystallization by inhibiting the growth of calcium oxalate crystals. Kidney Int 60: 77-82, 2001.
    • (2001) Kidney Int , vol.60 , pp. 77-82
    • Hoyer, J.R.1    Asplin, J.R.2    Otvos, L.3
  • 25
    • 44449098317 scopus 로고    scopus 로고
    • Bone sialoprotein binding to matrix metalloproteinase-2 alters enzyme inhibition kinetics
    • Jain A, Fisher LW, Fedarko NS. Bone sialoprotein binding to matrix metalloproteinase-2 alters enzyme inhibition kinetics. Biochemistry 47: 5986-5995, 2008.
    • (2008) Biochemistry , vol.47 , pp. 5986-5995
    • Jain, A.1    Fisher, L.W.2    Fedarko, N.S.3
  • 27
    • 58149109303 scopus 로고    scopus 로고
    • Recent advances in the renal-skeletal-gut axis that controls phosphate homeostasis
    • Kiela PR, Ghishan FK. Recent advances in the renal-skeletal-gut axis that controls phosphate homeostasis. Lab Invest 89: 7-14, 2009.
    • (2009) Lab Invest , vol.89 , pp. 7-14
    • Kiela, P.R.1    Ghishan, F.K.2
  • 29
    • 26944499850 scopus 로고    scopus 로고
    • Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia
    • Liu S, Brown TA, Zhou J, Xiao ZS, Awad H, Guilak F, Quarles LD. Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia. J Am Soc Nephrol 16: 1645-1653, 2005.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1645-1653
    • Liu, S.1    Brown, T.A.2    Zhou, J.3    Xiao, Z.S.4    Awad, H.5    Guilak, F.6    Quarles, L.D.7
  • 31
    • 33947385485 scopus 로고    scopus 로고
    • Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity
    • Liu S, Rowe PS, Vierthaler L, Zhou J, Quarles LD. Phosphorylated acidic serine-aspartate-rich MEPE-associated motif peptide from matrix extracellular phosphoglycoprotein inhibits phosphate regulating gene with homologies to endopeptidases on the X-chromosome enzyme activity. J Endocrinol 192: 261-267, 2007.
    • (2007) J Endocrinol , vol.192 , pp. 261-267
    • Liu, S.1    Rowe, P.S.2    Vierthaler, L.3    Zhou, J.4    Quarles, L.D.5
  • 33
    • 0027025335 scopus 로고
    • Phosphate transport in brush border membranes from uremic rats. Response to phosphonoformic acid
    • Loghman-Adham M, Szczepanska-Konkel M, Dousa TP. Phosphate transport in brush border membranes from uremic rats. Response to phosphonoformic acid. J Am Soc Nephrol 3: 1253-1259, 1992.
    • (1992) J Am Soc Nephrol , vol.3 , pp. 1253-1259
    • Loghman-Adham, M.1    Szczepanska-Konkel, M.2    Dousa, T.P.3
  • 36
    • 57149108326 scopus 로고    scopus 로고
    • The phosphatonin matrix extracellular phosphoglycoprotein (MEPE) inhibits renal intestinal phosphate transport in vivo
    • Marks J, Churchill LJ, Edward SD, Unwin R. The phosphatonin matrix extracellular phosphoglycoprotein (MEPE) inhibits renal intestinal phosphate transport in vivo. J Am Soc Nephrol 19: 2313-2320, 2008.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2313-2320
    • Marks, J.1    Churchill, L.J.2    Edward, S.D.3    Unwin, R.4
  • 37
    • 41549134046 scopus 로고    scopus 로고
    • Degradation of MEPE, DMP1, and release of SIBLING ASARM peptides (minhibins): ASARM peptide(s) are directly responsible for defective mineralization in HYP
    • Martin A, David V, Laurence JS, Schwarz PM, Lafer EM, Hedge AM, Rowe PS. Degradation of MEPE, DMP1, and release of SIBLING ASARM peptides (minhibins): ASARM peptide(s) are directly responsible for defective mineralization in HYP. Endocrinology 149: 1757-1772, 2008.
    • (2008) Endocrinology , vol.149 , pp. 1757-1772
    • Martin, A.1    David, V.2    Laurence, J.S.3    Schwarz, P.M.4    Lafer, E.M.5    Hedge, A.M.6    Rowe, P.S.7
  • 39
    • 19344367077 scopus 로고    scopus 로고
    • Altered cathepsin D metabolism in PHEX antisense human osteoblast cells
    • Matsumoto N, Jo OD, Shih RN, Yanagawa N. Altered cathepsin D metabolism in PHEX antisense human osteoblast cells. Biochem Biophys Res Commun 332: 248-253, 2005.
    • (2005) Biochem Biophys Res Commun , vol.332 , pp. 248-253
    • Matsumoto, N.1    Jo, O.D.2    Shih, R.N.3    Yanagawa, N.4
  • 40
    • 0023552808 scopus 로고
    • Comparative effects of intravenous diphosphonates on calcium and skeletal metabolism in man
    • McCloskey EV, Yates AJ, Beneton MN, Galloway J, Harris S, Kanis JA. Comparative effects of intravenous diphosphonates on calcium and skeletal metabolism in man. Bone 8: S35-S41, 1987.
    • (1987) Bone , vol.8
    • McCloskey, E.V.1    Yates, A.J.2    Beneton, M.N.3    Galloway, J.4    Harris, S.5    Kanis, J.A.6
  • 42
    • 0019798269 scopus 로고
    • Tubular handling of phosphate along the nephron of thyroparathyroidectomized rats injected with ethane-1-hydroxy-1,1-diphosphonate
    • Muhlbauer RC, Bonjour JP, Fleisch H. Tubular handling of phosphate along the nephron of thyroparathyroidectomized rats injected with ethane-1-hydroxy-1,1-diphosphonate. Clin Sci (Lond) 60: 171-177, 1981.
    • (1981) Clin Sci (Lond) , vol.60 , pp. 171-177
    • Muhlbauer, R.C.1    Bonjour, J.P.2    Fleisch, H.3
  • 44
    • 0842276878 scopus 로고    scopus 로고
    • Functional properties of cultured normal and vitamin D receptor knockout mice calvarial osteoblasts (Abstract)
    • Okano T, Tsugawa N, Hirami C, Kato S. Functional properties of cultured normal and vitamin D receptor knockout mice calvarial osteoblasts (Abstract). J Bone Miner Res 18, Suppl 2: S141, 2003.
    • (2003) J Bone Miner Res , vol.18 , Issue.SUPPL. 2
    • Okano, T.1    Tsugawa, N.2    Hirami, C.3    Kato, S.4
  • 45
  • 46
    • 37549059576 scopus 로고    scopus 로고
    • Dentin matrix protein 1 (DMP1): New and important roles for biomineralization and phosphate homeostasis
    • Qin C, D'Souza R, Feng JQ. Dentin matrix protein 1 (DMP1): new and important roles for biomineralization and phosphate homeostasis. J Dent Res 86: 1134-1141, 2007.
    • (2007) J Dent Res , vol.86 , pp. 1134-1141
    • Qin, C.1    D'souza, R.2    Feng, J.Q.3
  • 49
    • 11244352700 scopus 로고    scopus 로고
    • The wrickkened pathways of FGF23, MEPE and PHEX
    • Rowe PSN. The wrickkened pathways of FGF23, MEPE and PHEX. Crit Rev Oral Biol Med 15: 264-281, 2004.
    • (2004) Crit Rev Oral Biol Med , vol.15 , pp. 264-281
    • Rowe, P.S.N.1
  • 51
    • 12344250943 scopus 로고    scopus 로고
    • Surface plasmon resonance (SPR) confirms MEPE binds to PHEX via the MEPE-ASARM-motif: A model for impaired mineralization in X-linked rickets (HYP)
    • Rowe PSN, Garrett IR, Schwarz PM, Carnes DL, Lafer EM, Mundy GR, Gutierrez GE. Surface plasmon resonance (SPR) confirms MEPE binds to PHEX via the MEPE-ASARM-motif: a model for impaired mineralization in X-linked rickets (HYP). Bone 36: 33-46, 2005.
    • (2005) Bone , vol.36 , pp. 33-46
    • Rowe, P.S.N.1    Garrett, I.R.2    Schwarz, P.M.3    Carnes, D.L.4    Lafer, E.M.5    Mundy, G.R.6    Gutierrez, G.E.7
  • 54
    • 70350330869 scopus 로고    scopus 로고
    • Bone formation regulates circulating concentrations of fibroblast growth factor 23
    • Samadfam R, Richard C, Nguyen-Yamamoto L, Bolivar I, Goltzman D. Bone formation regulates circulating concentrations of fibroblast growth factor 23. Endocrinology 150: 4835-4845, 2009.
    • (2009) Endocrinology , vol.150 , pp. 4835-4845
    • Samadfam, R.1    Richard, C.2    Nguyen-Yamamoto, L.3    Bolivar, I.4    Goltzman, D.5
  • 55
    • 0036156762 scopus 로고    scopus 로고
    • Effects of PHEX antisense in human osteoblast cells
    • Shih NR, Jo OD, Yanagawa N. Effects of PHEX antisense in human osteoblast cells. J Am Soc Nephrol 13: 394-399, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 394-399
    • Shih, N.R.1    Jo, O.D.2    Yanagawa, N.3
  • 56
    • 77957228924 scopus 로고    scopus 로고
    • Direct micropuncture evidence that matrix extracellular phosphoglycoprotein inhibits proximal tubular phosphate reabsorption
    • Shirley DG, Faria NJ, Unwin RJ, Dobbie H. Direct micropuncture evidence that matrix extracellular phosphoglycoprotein inhibits proximal tubular phosphate reabsorption. Nephrol Dial Transplant 25: 3191-3195, 2010.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3191-3195
    • Shirley, D.G.1    Faria, N.J.2    Unwin, R.J.3    Dobbie, H.4
  • 59
    • 33947111420 scopus 로고    scopus 로고
    • Phosphate transport: Molecular basis, regulation and pathophysiology
    • Tenenhouse HS. Phosphate transport: molecular basis, regulation and pathophysiology. J Steroid Biochem Mol Biol 103: 572-577, 2007.
    • (2007) J Steroid Biochem Mol Biol , vol.103 , pp. 572-577
    • Tenenhouse, H.S.1
  • 62
    • 34250023449 scopus 로고    scopus 로고
    • Urinary acidification assessed by simultaneous furosemide and fludrocortisone treatment: An alternative to ammonium chloride
    • Walsh SB, Shirley DG, Wrong OM, Unwin RJ. Urinary acidification assessed by simultaneous furosemide and fludrocortisone treatment: an alternative to ammonium chloride. Kidney Int 71: 1310-1316, 2007.
    • (2007) Kidney Int , vol.71 , pp. 1310-1316
    • Walsh, S.B.1    Shirley, D.G.2    Wrong, O.M.3    Unwin, R.J.4
  • 63
    • 0016582540 scopus 로고
    • Changes in the renal and extrarenal handling of phosphate induced by disodium etidronate (EHDP) in man
    • Walton RJ, Russell RG, Smith R. Changes in the renal and extrarenal handling of phosphate induced by disodium etidronate (EHDP) in man. Clin Sci Mol Med 49: 45-56, 1975.
    • (1975) Clin Sci Mol Med , vol.49 , pp. 45-56
    • Walton, R.J.1    Russell, R.G.2    Smith, R.3
  • 65
    • 43549106530 scopus 로고    scopus 로고
    • MEPE overexpres-sion in osteocytes of Dmp1 null mice by activation of the PKA/CREB pathway (Meeting Abstract)
    • Yang W, Harris SE, Raw P, Feng J, Gluhak-Heinrich J. MEPE overexpres-sion in osteocytes of Dmp1 null mice by activation of the PKA/CREB pathway (Meeting Abstract). J Bone Miner Res 21: S136-S136, 2006.
    • (2006) J Bone Miner Res , vol.21
    • Yang, W.1    Harris, S.E.2    Raw, P.3    Feng, J.4    Gluhak-Heinrich, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.