An increase in serum uric acid concentrations is associated with an increase in the Framingham risk score in Korean adults

Clinical Chemistry and Laboratory Medicine

Volumn 49, Issue 5, 2011, Pages 909-914

  Nam, Ga Eun ^a   Lee, Kyung Shik ^b   Park, Yong Gyu ^c   Cho, Kyung Hwan ^a   Lee, Seung Hwan ^a   Ko, Byung Joon ^a   Kim, Do Hoon ^d  

^a Korea University College of Medicine   (South Korea)

^b Gachon University College of Medicine   (South Korea)

^c The Catholic University of Korea College of Medicine   (South Korea)

^d Korea University College of Medicine   (South Korea)

Author keywords

cardiovascular disease; coronary heart disease; Framingham risk score; risk factors; uric acid

Indexed keywords

C REACTIVE PROTEIN; CREATININE; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; URIC ACID;

ADULT; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE MARKER; FEMALE; FRAMINGHAM RISK SCORE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HUMAN; HYPERURICEMIA; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; KOREA; LEUKOCYTE COUNT; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PHYSICIAN; PRIORITY JOURNAL; SCORING SYSTEM; TRIACYLGLYCEROL BLOOD LEVEL; URIC ACID BLOOD LEVEL;

ADULT; AGE FACTORS; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CORONARY DISEASE; FEMALE; HUMANS; KOREA; MALE; MIDDLE AGED; RISK FACTORS; URIC ACID; YOUNG ADULT;

EID: 79954463886     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2011.124     Document Type: Article

References (31)

1. Halil M, Yavuz B, Yavuz BB, Cankurtaran M, Dede DS, Ulger Z, et al. Novel cardiovascular risk factors in the elderly and their correlation with the Framingham risk score. J Cardiovasc Med (Hagerstown) 2008;9:683-7.
2. Rifkin DE, Katz R, Chonchol M, Fried LF, Cao J, de Boer IH, et al. Albuminuria, impaired kidney function and cardiovascular outcomes or mortality in the elderly Nephrol Dial Transplant 2010;25:1560-7.
3. Cannon CP. Mixed dyslipidemia, metabolic syndrome, diabetes mellitus, and cardiovascular disease: clinical implications. Am J Cardiol 2008;102:5L-9L.
4. Demircan S, Yazici M, Durna K, Kilicaslan F, Demir S, Pinar M, et al. The importance of gamma-glutamyltransferase activity in patients with coronary artery disease. Clin Cardiol 2009;32: 220-5.
5. Aukrust P, Halvorsen B, Yndestad A, Ueland T, Oie E, Otterdal K, et al. Chemokines and cardiovascular risk. Arterioscler Thromb Vasc Biol 2008;28:1909-19.
6. Ruggiero C, Cherubini A, Ble A, Bos AJ, Maggio M, Dixit VD, et al. Uric acid and inflammatory markers. Eur Heart J 2006;27:1174-81.
7. Executive Summary of The Third Report of The National Cho-lesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). J Am Med Assoc 2001; 285:2486-97.
8. Niskanen LK, Laaksonen DE, Nyyssonen K, Alfthan G, Lakka HM, Lakka TA, et al. Uric acid levels as a risk factor for car-diovascular and all-cause mortality in middle-aged men. Arch Int Med 2004;164:1546-51. (Pubitemid 38970476)
9. Gagliardi AC, Miname MH, Santos RD. Uric acid: a marker of increased cardiovascular risk. Atherosclerosis 2009;202:11-7.
10. Johnson RJ, Kang DH, Feig D, Kivlighn S, Kanellis J, Wata-nabe S, et al. Is there a pathogenetic role for uric acid in hyper-tension and cardiovascular and renal disease? Hypertension 2003;41:1183-90. (Pubitemid 36706063)
11. Hoieggen A, Alderman MH, Kjeldsen SE, Julius S, Devereux RB, De Faire U, et al. The impact of serum uric acid on car-diovascular outcomes in the LIFE study Kidney Int 2004;65: 1041-9. (Pubitemid 38251080)
12. Ioachimescu AG, Brennan DM, Hoar BM, Kashyap SR, Hoog-werf BJ. Serum uric acid, mortality and glucose control in patients with type 2 diabetes mellitus: a PreCIS database study Diabet Med 2007;24:1369-74. (Pubitemid 350179450)
13. Ioachimescu AG, Brennan DM, Hoar BM, Hazen SL, Hoog-werf BJ. Serum uric acid is an independent predictor of all-cause mortality in patients at high risk of cardiovascular disease: a preventive cardiology information system (PreCIS) database cohort study Arthritis Rheum 2008;58:623-30. (Pubitemid 351294901)
14. Lippi G, Montagnana M, Franchini M, Favaloro EJ, Targher G The paradoxical relationship between serum uric acid and car-diovascular disease. Clin Chim Acta 2008;392:1-7.
15. Numata T, Miyatake N, Wada J, Makino H. Comparison of serum uric acid levels between Japanese with and without met-abolic syndrome. Diabetes Res Clin Pract 2008;80:e1-5.
16. Wilson PW, D'Agostino RB, Parise H, Sullivan L, Meigs JB. Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 2005;112:3066-72. (Pubitemid 43113437)
17. Lee JG, Lee S, Kim YJ, Jin HK, Cho BM, Jeong DW, et al. Multiple biomarkers and their relative contributions to identi-fying metabolic syndrome. Clin Chim Acta 2009;408:50-5.
18. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resis-tance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-9. (Pubitemid 15018832)
19. Chen Y, Hou M, Li Y, Traverse JH, Zhang P, Salvemini D, et al. Increased superoxide production causes coronary endothelial dysfunction and depressed oxygen consumption in the failing heart. Am J Physiol Heart Circ Physiol 2005;288:H133-41. (Pubitemid 40023840)
20. Ginsberg MH, Kozin F, O'Malley M, McCarty DJ. Release of platelet constituents by monosodium urate crystals. J Clin Invest 1977;60:999-1007. (Pubitemid 8223125)
21. Ward HJ. Uric acid as an independent risk factor in the treat-ment of hypertension. Lancet 1998;352:670-1. (Pubitemid 28398697)
22. Wortmann RL. Disorders of purine and pyrimidine metabolism. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, et al., editors. Harrison's principles of internal medicine. New York: McGraw-Hill, 2008. p. 2444-7.
23. Puig JG, Ruilope LM. Uric acid as a cardiovascular risk factor in arterial hypertension. J Hypertens 1999;17:869-72. (Pubitemid 29322173)
24. Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N Engl J Med 2008;359:1811-21.
25. D'Agostino RB Sr., Grundy S, Sullivan LM, Wilson P. Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation. J Am Med Assoc 2001;286:180-7. (Pubitemid 32640849)
26. Glantzounis GK, Tsimoyiannis EC, Kappas AM, Galaris DA. Uric acid and oxidative stress. Curr Pharm Des 2005;11:4145-51. (Pubitemid 41672464)
27. Nieto FJ, Iribarren C, Gross MD, Comstock GW, Cutler RG Uric acid and serum antioxidant capacity: a reaction to athros-clerosis? Atherosclerosis 2000;148:131-9.
28. Heinig M, Johnson RJ. Role of uric acid in hypertension, renal disease, and metabolic syndrome. Cleve Clin J Med 2006;73: 1059-64. (Pubitemid 44883981)
29. Fang J, Alderman MH. Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey J Am Med Assoc 2000;283:2404-10. (Pubitemid 30257539)
30. Strasak AM, Kelleher CC, Brant LJ, Rapp K, Ruttmann E, Concin H, et al. Serum uric acid is an independent predictor for all major forms of cardiovascular death in 28,613 elderly women: a prospective 21-year follow-up study Int J Cardiol 2008;125:232-9.
31. Barzi F, Patel A, Gu D, Sritara P, Lam TH, Rodgers A, et al. Cardiovascular risk prediction tools for populations in Asia. J Epidemiol Community Health 2007;61:115-21. (Pubitemid 46174217)