Imaging targeted-agent binding in vivo with two probes

Journal of Biomedical Optics

Volumn 15, Issue 3, 2010, Pages

  Pogue, Brian W ^a,b,c   Samkoe, Kimberley S ^a   Hextrum, Shannon ^a   O'Hara, Julia A ^a,b   Jermyn, Michael ^a   Srinivasan, Subhadra ^a   Hasan, Tayyaba ^c  

^a DARTMOUTH COLLEGE   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Fluorescence; Fluorescence spectroscopy; Image analysis; Image processing; Imaging; Molecules

Indexed keywords

BINDING RATE; BINDING RATE CONSTANTS; EPIDERMAL GROWTH FACTORS; FLUORESCENT DYES; IN-VIVO; NON-INVASIVE ASSESSMENTS; NON-TARGETED; ORTHOTOPIC; RECEPTOR TARGETING; SPATIAL LOCALIZATION; THERAPEUTIC AGENTS;

FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; IMAGE PROCESSING; RATE CONSTANTS; TUMORS;

PROBES;

DIAGNOSTIC AGENT; EPIDERMAL GROWTH FACTOR; FLUORESCENT DYE;

ANIMAL; BIOLOGICAL MODEL; HUMAN; IMAGE PROCESSING; KINETICS; LETTER; METABOLISM; METHODOLOGY; MOUSE; PANCREAS TUMOR; SPECTROFLUOROMETRY; STATISTICAL MODEL; TUMOR CELL LINE; WHOLE BODY IMAGING; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; EPIDERMAL GROWTH FACTOR; FLUORESCENT DYES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETICS; LINEAR MODELS; MICE; MODELS, BIOLOGICAL; PANCREATIC NEOPLASMS; SPECTROMETRY, FLUORESCENCE; TRANSPLANTATION, HETEROLOGOUS; WHOLE BODY IMAGING;

EID: 79954460985     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3449109     Document Type: Article

References (7)

1. B. Dhesy-Thind, K. I. Pritchard, H. Messersmith, F. O'Malley, L. Elavathil, and M. Trudeau, "HER2/neu in systemic therapy for women with breast cancer: a systematic review," Breast Cancer Res. Treat 109(2), 209-229 (2008). (Pubitemid 351644854)
2. G. P. Adams and L. M. Weiner, "Monoclonal antibody therapy of cancer," Nat. Biotechnol. 23(9), 1147-1157 (2005). (Pubitemid 41486396)
3. J. J. Farrell, M. van Rijnsoever, and H. Elsaleh, "Early detection markers in pancreas cancer," Cancer Biomark. 1(2-3), 157-175 (2005).
4. P. A. Philip, M. Mooney, D. Jaffe, G. Eckhardt, M. Moore, N. Meropol, L. Emens, E. O'Reilly, M. Korc, L. Ellis, J. Benedetti, M. Rothenberg, C. Willett, M. Tempero, A. Lowy, J. Abbruzzese, D. Simeone, S. Hingorani, J. Berlin, and J. Tepper, "Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment," J. Clin. Oncol. 27(33), 5660-5669 (2009).
5. A. J. Durkin, P. M. Bloomston, A. S. Rosemurgy, N. Giarelli, D. Cojita, T. J. Yeatman, and E. E. Zervos, "Defining the role of the epidermal growth factor receptor in pancreatic cancer grown in vitro," Am. J. Surg. 186, 431-436 (2003). (Pubitemid 37352823)
6. L. W. Seymour, "Passive tumor targeting of soluble macromolecules and drug conjugates," Crit. Rev. Ther. Drug Carrier Syst. 9(2), 135-187 (1992).
7. D. W. Bartlett, H. Su, I. J. Hildebrandt, W. A. Weber, and M. E. Davis, "Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imaging," Proc. Natl. Acad. Sci. U.S.A. 104(39), 15549-15554 (2007). (Pubitemid 47502954)