Multivariate optimization and validation of a CE method for simultaneous analysis of dorzolamide hydrochloride and timolol maleate in ophthalmic solution

Chromatographia

Volumn 73, Issue 5-6, 2011, Pages 541-548

  Palabiyik, Ismail Murat ^a   Caglayan, Mehmet Gokhan ^a   Onur, Feyyaz ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Capillary electrophoresis; Dorzolamide hydrochloride; Multivariate optimization; Response surface methodology; Timolol maleate

Indexed keywords

DORZOLAMIDE; DORZOLAMIDE PLUS TIMOLOL; DORZOLAMIDE PLUS TIMOLOL MALEATE; EYE DROPS; SODIUM DIHYDROGEN PHOSPHATE; TIMOLOL MALEATE;

ACCURACY; ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; INTERMETHOD COMPARISON; PH; PRIORITY JOURNAL; RESPONSE SURFACE METHOD; SPECTROPHOTOMETRY; TEMPERATURE; VALIDATION STUDY;

EID: 79954438336     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1007/s10337-010-1901-6     Document Type: Article

References (10)

1. USP DI (1999) 19th Edition, Volume II, Advice for the Patient, Drug Information in Lay Language. Micromedex Inc., USA
2. Myers RH, Montgomery DC (2002) Response Surface Methodology: Process and Product Optimization Using Designed Experiments. John Wiley & Sons, INC, Canada
3. IM Palabiyik F Onur 2010 Anal Sci 26 8 853 859 10.2116/analsci.26.853 1:CAS:528:DC%2BC3cXhtFWnu77F
4. N Erk 2002 J Pharm Biomed Anal 28 2 391 397 10.1016/S0731-7085(01)00627-6 1:CAS:528:DC%2BD38XisFWnsbs%3D (Pubitemid 34266919)
5. N Erk 2003 Pharmazie 58 7 491 493 1:CAS:528:DC%2BD3sXlsVOjs7k%3D
6. LI Bebawy 2002 J Pharm Biomed Anal 27 5 737 746 10.1016/S0731-7085(01) 00529-5 1:CAS:528:DC%2BD38XovFChtQ%3D%3D (Pubitemid 34117661)
7. 1) (2005) International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use
8. H Fabre 1996 J Pharm Biomed Anal 14 1125 1132 10.1016/S0731-7085(96) 01770-0 1:CAS:528:DyaK28Xks1Sjt70%3D (Pubitemid 26235166)
9. Otto M (1999) Chemometrics: Statistics and Computer Application in Analytical Chemistry. WILEY-VCH, Weinheim, Germany
10. Reviewer Guidance, Validation of Chromatographic Methods (1994) Center for Drug Evaluation and Research, U. S. Food and Drug Administration, FDA, Rockville, USA