Metrenperone enhances collagen turnover and remodeling in the early stages of healing of tendon injury in rabbit

Archives of Orthopaedic and Trauma Surgery

Volumn 130, Issue 12, 2010, Pages 1451-1457

  Oryan, Ahmad ^a   Silver, Ian A ^b   Goodship, Allen E ^c  

^a SHIRAZ UNIVERSITY   (Iran)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Biomechanics; Healing; Metrenperone; Tendon; Ultrastructure

Indexed keywords

COLLAGEN; COLLAGENASE; DNA; METRENPERONE; PIPERIDINE DERIVATIVE; SEROTONIN 2 ANTAGONIST;

ANIMAL; ARTICLE; BIOMECHANICS; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FEMALE; METABOLISM; PATHOLOGY; RABBIT; TENDON; TENDON INJURY; TENSILE STRENGTH; ULTRASTRUCTURE; WOUND HEALING;

ANIMALS; BIOMECHANICS; COLLAGEN; COLLAGENASES; DNA; FEMALE; PIPERIDINES; RABBITS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS; TENDON INJURIES; TENDONS; TENSILE STRENGTH; WOUND HEALING;

EID: 79954431108     PISSN: 09368051     EISSN: 14343916     Source Type: Journal    
DOI: 10.1007/s00402-010-1057-8     Document Type: Article

References (37)

1. Asheim A (1964) Surgical treatment of tendon injuries in the horse. J Am Vet Med Assoc 145:447-451
2. Fackelman GE (1973) The nature of tendon damage and its repair. Equine Vet J 5:141-149
3. Genicot B, Mouligneau F, Rollin F, Lindsey JK, Close R, Lekeux P (1993) Economic, clinical and functional consequences of a treatment using metrenperone during an outbreak of shipping fever in cattle. Vet Rec 132:245-247 (Pubitemid 23098061)
4. Goodship AE, Brown PN, Yeats JJ, Jenkins DHR, Silver IA (1980) An assessment of filamentous carbon fiber for treatment of tendon injury in the horse. Vet Rec 106:217-221
5. Goodship AE, Wilcock SA, Shah JS (1985) The development of tissue around various prosthetic implants used as replacements for ligaments and tendons. Clin Orthop Relat Res 186:61-68 (Pubitemid 15028311)
6. Goodship AE, Birch HL, Wilson AM (1994) The pathobiology and repair of tendon and ligament injury. Vet Clin North Am Equine Pract 10:323-349
7. Hegedus EJ, Cook C, Brennan M, Wyland D, Garrison JC, Driesner D (2009) Vascularity and tendon pathology in rotator cuff: a review of literature and implications for rehabilitation and surgery. Br J Sports Med (in press). doi:10.1136/bjsm.2008.053769
8. 2 receptor blockade to study serotonin-induced pathology. TIPS Rev 4:198-206
9. Janssen PAJ (1985) Pharmacology of potent and selective S2-serotonergic antagonists. J Cardiovasc Pharmacol 7 (Suppl):2-11
10. Jepsen KJ, Wu F, Peragallo JH, Paul J, Roberts L, Ezura Y, Oldberg A, Birk DE, Chakravarti S (2002) A syndrome of joint laxity and impaired tendon integrity in lumican and fibromodullin deficient mice. J Biol Chem 277:35532-35540
11. Letho H, Duance VC, Restall D (1985) Collagen and fibronectin in a healing skeletal muscle injury. J Bone Joint Surg 67B:820-828
12. 2-receptor blockade, by metrenperone, in healthy calves. Vet J 157:31-37
13. Milne FJ (1961) Thoughts and observations on counterirritation in the horse. Zentralbl Veterinärmed 8:1069-1140
14. Nobin BA, Nobin A, Owman C, Tornebrandt K (1985) Serotonergic mechanisms in isolated human peripheral arteries and veins. J Cardiovasc Pharmacol 7(Suppl 7):52-55
15. O'Brien M (1997) Structure and metabolism of tendons. Scand J Med Sci Sports 7:55-61
16. Oryan A, Peyghan R, Emami MJ (1993) The effects of physical activity on tendon healing. Iran J Med Sci 18:13-21
17. Oryan A (1995) Induction of soft connective tissue formation by various prosthetic implants. Transplant Proc 27:2754-2755
18. Oryan A (1995) Role of collagen in soft connective tissue wound healing. Transplant Proc 27:2759-2761
19. Oryan A, Peyghan R (1995) Morphological and biomechanical characteristics of tendons and ligaments. J Vet Sch Tehran Univ 50:13-38
20. Oryan A, Khalafinezhad A, Toloo N, Soltanirad MN (2007) Effects of 4-chloro-2, 6-bis-(2hydroxyl-benzyl)-phenol on healing of skin wounds and growth of bacteria. J Vet Med A 54:585-591 (Pubitemid 350206006)
21. Oryan A, Shoushtari AH (2008) Histology and ultrastructure of the developing superficial digital flexor tendon in rabbits. Anat Histol Embryol 37:134-140 (Pubitemid 351366551)
22. Oryan A, Silver IA, Goodship AE (2008) Response of a collagenase-induced tendon injury to treatment with a polysulphated glycosaminoglycan (Adequan). Connect Tissue Res 49:351-360
23. Provenzano P, Vanderby R (2006) Collagen fibril morphology and organization: implication for force transmission in ligament and tendon. Matrix Biol 25:55-61
24. Riemersma DJ, Schamhardt HC (1982) The cryo-jaw, a clamp designed for in vitro rheology studies of horse digital flexor tendons. J Biomech 15:619-620
25. Sarrafzadeherezaei F, Oryan A, Dehghani S (1999) Effects of electrical stimulation on partial and complete tendon ruptures. Res Med Sci 23:169-175
26. Sharma P, Maffulli N (2006) Biology of tendon injury: healing, modeling and remodeling. J Musculoskelet Neuronal Interact 6:181-190 (Pubitemid 44193219)
27. Silver IA, Brown PN, Goodship AE, Lynon LE, McCullagh KG, Perry GC, Williams IF (1983) A clinical and experimental study of tendon injury, healing and treatment in the horse. Equine Vet J Suppl 1:1-43
28. Van der Meulen JC, Leistikow PA (1997) Tendon healing. Clin Plast Surg 4:439-458
29. Viidik A (1969) Tensile strength properties of Achilles tendon system in trained and untrained rabbits. Acta Orthop Scand 40:261-272
30. Watkins JP, Auer JA, Gay S, Morgan SJ (1985) Healing of surgically created defects in the equine superficial digital flexor tendon: collagen-type transformation and tissue morphologic reorganization. Am J Vet Res 46:2091-2096
31. Webbon PM (1973) Equine tendon stress injuries. Equine Vet J 5:58-64
32. Williams IF, Heaton JA, McCullagh KG (1980) Cell morphology and collagen types in equine tendon scar. Res Vet Sci 28:302-310 (Pubitemid 10042917)
33. Williams IF (1986) Cellular and biochemical composition of healing tendon. In: Jenkins DHR (ed) Ligament injuries and their treatment. Chapman & Hall, London, pp 43-57
34. Williams IF, Nicholls JS, Goodship AE, Silver IA (1986) Experimental treatment of tendon injury with heparin. Br J Plast Surg 39:367-372 (Pubitemid 16098682)
35. Woessner JF (1961) The determination of hydroxyproline in tissue and protein samples containing small proportions of this amino acid. Arch Biochem Biophys 93:440-447
36. Yagishita K, Sekiya I, Sakaguchi Y, Shinomiya K, Muneta T (2005) The effect of hyaluronan on tendon healing in rabbits. Arthroscopy 21:1330-1336 (Pubitemid 41735198)
37. Zhang G, Young BB, Ezura Y, Favata M, Soslowsky LJ, Chakravati S, Birk DE (2005) Development of tendon structure and function: regulation of collagen fibrillogenesis. J Musculoskelet Neuronal Interact 5:5-21 (Pubitemid 40667619)