Early intravenous immunoglobin (two-dose regimen) in the management of severe Rh hemolytic disease of newborn-a prospective randomized controlled trial

European Journal of Pediatrics

Volumn 170, Issue 4, 2011, Pages 461-467

  Elalfy, Mohsen Saleh ^a   Elbarbary, Nancy Samir ^a   Abaza, Heba Wegdan ^b  

^a AIN SHAMS UNIVERSITY   (Egypt)

^b El Galaa Hospital   (Egypt)

Author keywords

Exchange blood transfusion; Intravenous immunoglobulin; Phototherapy; Rh hemolytic disease of newborn

Indexed keywords

BILIRUBIN; IMMUNOGLOBULIN;

ARTICLE; BLOOD GROUP RHESUS SYSTEM; CONTROLLED STUDY; DISEASE SEVERITY; DRUG MEGADOSE; EXCHANGE BLOOD TRANSFUSION; FEMALE; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN HEMOLYTIC DISEASE; PHOTOTHERAPY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

BILIRUBIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ERYTHROBLASTOSIS, FETAL; EXCHANGE TRANSFUSION, WHOLE BLOOD; FEMALE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; INFANT, NEWBORN; INFUSIONS, INTRAVENOUS; LENGTH OF STAY; MALE; PHOTOTHERAPY; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 79954425577     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-010-1310-8     Document Type: Article

References (32)

1. F Alpay SU Sarici V Okutan G Erdem O Ozcan E Gokcay 1999 High dose intravenous immunoglobulin therapy in neonatal immune hemolytic jaundice Acta Paediatr 88 2 216 219 10102158 10.1080/08035259950170420 1:STN:280: DyaK1M3gtVarsw%3D%3D (Pubitemid 29124328)
2. American Academy of Pediatrics 2004 Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation (Subcommittee on Hyper-bilirubinemia) Pediatrics 114 1 297 316 10.1542/peds.114.1.297 (Pubitemid 38857607)
3. Sh Behjati S Sagheb S Aryasepehr B Yaghmai 2009 Adverse events associated with neonatal exchange transfusion for hyperbilirubinemia Indian J Pediatr 76 1 83 85 19391007 10.1007/s12098-009-0033-1
4. JE Colletti S Kothari DM Jackson KP Kilgore K Barringer 2007 An emergency medicine approach to neonatal hyperbilirubinemia Emerg Med Clin North Am 25 4 1117 1135 17950138 10.1016/j.emc.2007.07.007 vii (Pubitemid 47562657)
5. N Cooper 2009 Intravenous immunoglobulin and anti-Rh D therapy in the management of immune thrombocytopenia Hematol Oncol Clin North Am 23 6 1317 1327 19932436 10.1016/j.hoc.2009.09.002
6. A Cortey Y Brossard 2006 Prevention of fetomaternal rhesus-D allo-immunization. Practical aspects J Gynecol Obstet Biol Repord (Paris) 35 1 suppl 1S123 1S130 1:STN:280:DC%2BD287gvV2jsw%3D%3D
7. N Demirel M Aydin A Zenciroglu AY Bas N Yarali N Okumus G Cinar MS Ipek 2009 Neonatal thrombo-embolism: risk factors, clinical features and outcome Ann Trop Paediatr Dec 29 4 271 279 10.1179/027249309X12547917868961 1:STN:280:DC%2BD1Mjosleqsw%3D%3D
8. J Figueras-Aloy JM Rodriguez-Miguelez M Iriondo-Sanz, et al. 2010 Intravenous immunoglobulin and necrotizing enterocolitis in newborns with hemolytic disease Pediatrics 125 1 139 144 19948572 10.1542/peds.2009-0676
9. G Girish D Chawla R Agarwal VK Paul Ak Deorari 2008 Efficacy of two dose regimes of intravenous immunoglobulin in Rh hemolytic disease of newborn-a randomized controlled trial Indian Pediatr 45 8 653 659 18723908 1:STN:280:DC%2BD1cnjsV2msw%3D%3D
10. P Gobalakichenane C Lardennois S Galène-Gromez, et al. 2008 Perinatal management and neurological outcome of newborns hospitalized with rhesus hemolytic disease Gynécol Obstét Fertil 36 10 984 990 18804397 10.1016/j.gyobfe.2008.07.012 1:STN:280:DC%2BD1cnnslCmtQ%3D%3D
11. Gordon S (2001) Mononuclear phagocytes in immune defense. In: Roitt I, Brostoff J, Male D (eds) Immunology, 6th edn. Mosby, St. Louis, pp 155-156
12. R Gottstein RW Cooke 2003 Systemic review of intravenous immunoglobulin in hemolytic disease of the newborn Arch Dis Child Fetal Neonatal Ed 88 1 F6 F10 12496219 10.1136/fn.88.1.F6 1:STN:280:DC%2BD38jjtlWisw%3D%3D
13. A Greenough 1999 Rhesus disease: postnatal management and outcome Eur J Pediatr 158 9 689 693 10485296 10.1007/s004310051180 1:STN:280: DyaK1MvhtlejtA%3D%3D (Pubitemid 29390103)
14. C Hammerman M Kaplan 2000 Recent developments in the management of neonatal hyperbilirubinemia NeoReviews 1 19 24 10.1542/neo.1-2-e19
15. K Huizing J Røislien T Hansen 2008 Intravenous immune globulin reduces the need for exchange transfusions in rhesus and AB0 incompatibility Acta Paediatr 97 10 1362 1365 18616629 10.1111/j.1651-2227.2008.00915.x 1:CAS:528:DC%2BD1cXhsFems7fN
16. JM Kirk 2008 Neonatal jaundice: a critical review of the role and practice of bilirubin analysis Ann Clin Biochem 45 pt5 452 462 18753416 10.1258/acb.2008.008076 1:CAS:528:DC%2BD1cXht12itbjN
17. A Kriplani B Malhotra Singh K Mandal 2007 Fetal intravenous immunoglobulin therapy in rhesus hemolytic disease Gynecol Obstet Invest 63 3 176 180 17143009 10.1159/000097661 (Pubitemid 46514809)
18. MJ Maisels Ak McDonagh 2008 Phototherapy for neonatal jaundice N Engl J Med 358 9 920 928 18305267 10.1056/NEJMct0708376 1:CAS:528:DC%2BD1cXisF2mtb8%3D (Pubitemid 351397091)
19. A Malhotra E Carse 2009 Survey of management of neonatal haemolytic jaundice in Australasia J Paediatr Child Health 46 5 222 225 10.1111/j.1440-1754.2009.01674.x
20. AM Miqdad OB Abdelbasit MM Shaheed Mz Seidahmed AM Abomella OP Arcala 2004 Intravenous immunoglobulin therapy for significant hyperbilirubinemia in ABO hemolytic disease of the newborn J Matern Fetal Neonatal Med 6 3 163 166 10.1080/jmf.16.3.163.166 (Pubitemid 40006903)
21. KJ Moise 2008 Management of rhesus alloimmunization in pregnancy Obstet Gynecol 112 1 164 176 18591322 10.1097/AOG.0b013e31817d453c
22. F Monpoux C Dageville AM Maillotte S De Smet F Casagrande P Boutté 2009 High-dose intravenous immunoglobulin therapy and neonatal jaundice due to red blood cell alloimmunization Arch Pediatr 16 9 1289 1294 19586760 10.1016/j.arcped.2009.05.015 1:STN:280:DC%2BD1Mrls1Cjug%3D%3D
23. K Mukhopadhyay S Murki A Narang S Dutta 2003 Intravenous immunoglobulin in rhesus hemolytic disease Indian J Pediatr 70 9 697 699 14620183 10.1007/BF02724308 (Pubitemid 37295912)
24. CA Mundy 2005 Intravenous immunoglobulin in the management of hemolytic disease of the newborn Neonatal Netw 24 6 17 24 16383181
25. NA Murray IA Roberts 2007 Haemolytic disease of the newborn Arch Dis Child Fetal Neonatal Ed 92 2 F83 F88 17337672 10.1136/adc.2005.076794 (Pubitemid 46423817)
26. M Navarro S Negre S Golombek ML Matoses M Vento 2010 Intravenous immune globulin: clinical applications in the newborn NeoReviews 11 7 e370 e378 10.1542/neo.11-7-e370
27. D Oepkes P Adama van Scheltema 2007 Intrauterine fetal transfusions in the management of fetal anemia and fetal thrombocytopenia Semin Fetal Neonatal Med 12 6 432 438 17706475 10.1016/j.siny.2007.06.007 (Pubitemid 350030914)
28. IA Roberts 2008 The changing face of haemolytic disease of the newborn Early Hum Dev 84 8 515 523 18621490 10.1016/j.earlhumdev.2008.06.005
29. S Smits VE Wintjens FJ Walther E Lopriore 2008 Rhesus hemolytic disease of the newborn: postnatal management, associated morbidity and long term outcome Semin Fetal Neonatal Med 13 4 265 271 10.1016/j.siny.2008.02.005
30. LA Steiner MJ Bizzarro RA Ehrenkranz PG Gallagher 2007 A decline in the frequency of neonatal exchange transfusions and its effect on exchange-related morbidity and mortality Pediatrics 120 1 27 32 17606558 10.1542/peds.2006-2910 (Pubitemid 47036237)
31. G Tanyer Z Siklar Y Dallar Y Yildirmak V Tiras 2001 Multiple dose intravenous immunoglobulin treatment in neonatal immune hemolytic jaundice J Trop Pediatr 47 1 50 53 11245352 10.1093/tropej/47.1.50 1:STN:280: DC%2BD3M7ps1Oksg%3D%3D (Pubitemid 32170937)
32. L Voto H Sexer G Ferreiro J Tavosnanska J Orti ER Mathet M Margulies 1995 Neonatal administration of high dose intravenous immunoglobulin in rhesus hemolytic disease J Perinat Med 23 6 443 451 8904473 10.1515/jpme.1995.23.6.443 1:CAS:528:DyaK28XitlKqsro%3D (Pubitemid 26052734)