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Volumn 137, Issue 1-2, 2011, Pages 46-52

Reduction of antibody response against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol-peptide conjugates

Author keywords

Antibodies; Botulinum neurotoxin A; Immune suppression; Monomethoxypolyethylene glycol; Mouse protection assay; Synthetic peptides

Indexed keywords

ANTISERUM; BOTULINUM TOXIN A; MACROGOL; MONOMETHOXYPOLYETHYLENE GLYCOL; PEPTIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79954425296     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2011.02.002     Document Type: Article
Times cited : (8)

References (31)
  • 1
    • 77951018634 scopus 로고    scopus 로고
    • Mode of action of botulinum neurotoxins: current vaccination strategies and molecular immune recognition
    • Aoki K.R., Smith L.A., Atassi M.Z. Mode of action of botulinum neurotoxins: current vaccination strategies and molecular immune recognition. Crit Rev Immunol 2010, 30:167-187.
    • (2010) Crit Rev Immunol , vol.30 , pp. 167-187
    • Aoki, K.R.1    Smith, L.A.2    Atassi, M.Z.3
  • 2
    • 0033023671 scopus 로고    scopus 로고
    • Structure, activity, and immune (T and B cell) recognition of botulinum neurotoxins
    • Atassi M.Z., Oshima M. Structure, activity, and immune (T and B cell) recognition of botulinum neurotoxins. Crit Rev Immunol 1999, 19:219-260.
    • (1999) Crit Rev Immunol , vol.19 , pp. 219-260
    • Atassi, M.Z.1    Oshima, M.2
  • 3
    • 0002988277 scopus 로고    scopus 로고
    • Botulinum toxin: clinical implications of antigenicity and immunoresistance
    • Lippincott Williams and Wilkins, Philadelphia, M. Brin, J. Hallett, Jankovic (Eds.)
    • Jankovic J. Botulinum toxin: clinical implications of antigenicity and immunoresistance. Scientific and therapeutic aspects of botulinum toxin 2002, 409-415. Lippincott Williams and Wilkins, Philadelphia. M. Brin, J. Hallett, Jankovic (Eds.).
    • (2002) Scientific and therapeutic aspects of botulinum toxin , pp. 409-415
    • Jankovic, J.1
  • 4
    • 3042818315 scopus 로고    scopus 로고
    • Treatment of cervical dystonia with botulinum toxin
    • Jankovic J. Treatment of cervical dystonia with botulinum toxin. Mov Disord 2004, 19:S109-S115.
    • (2004) Mov Disord , vol.19
    • Jankovic, J.1
  • 6
    • 3042774054 scopus 로고    scopus 로고
    • Basic immunological aspects of botulinum toxin therapy
    • Atassi M.Z. Basic immunological aspects of botulinum toxin therapy. Mov Disord 2004, 19:S68-S84.
    • (2004) Mov Disord , vol.19
    • Atassi, M.Z.1
  • 7
    • 0031239673 scopus 로고    scopus 로고
    • Botulinum A toxin therapy: neutralizing and nonneutralizing antibodies-therapeutic consequences
    • Göschel H., Wohlfarth K., Frevert J., Dengler R., Bigalke H. Botulinum A toxin therapy: neutralizing and nonneutralizing antibodies-therapeutic consequences. Exp Neurol 1997, 147:96-102.
    • (1997) Exp Neurol , vol.147 , pp. 96-102
    • Göschel, H.1    Wohlfarth, K.2    Frevert, J.3    Dengler, R.4    Bigalke, H.5
  • 8
    • 0028345811 scopus 로고
    • Development of resistance to botulinum toxin type A in patients with torticollis
    • Greene P., Fahn S., Diamond B. Development of resistance to botulinum toxin type A in patients with torticollis. Mov Disord 1994, 9:213-217.
    • (1994) Mov Disord , vol.9 , pp. 213-217
    • Greene, P.1    Fahn, S.2    Diamond, B.3
  • 9
    • 0042381872 scopus 로고    scopus 로고
    • Botulinum toxin type B in antibody-induced botulinum toxin type A therapy failure
    • Dressler D., Bigalke H., Benecke R. Botulinum toxin type B in antibody-induced botulinum toxin type A therapy failure. J Neurol 2003, 250:967-969.
    • (2003) J Neurol , vol.250 , pp. 967-969
    • Dressler, D.1    Bigalke, H.2    Benecke, R.3
  • 10
    • 27644442316 scopus 로고    scopus 로고
    • Comparison of botulinum toxin serotypes A and B for the treatment of cervical dystonia
    • Comella C.L., Jankovic J., Shannon K.M., Tsui J., Swenson M., Leurgans S., et al. Comparison of botulinum toxin serotypes A and B for the treatment of cervical dystonia. Neurology 2005, 65:1423-1429.
    • (2005) Neurology , vol.65 , pp. 1423-1429
    • Comella, C.L.1    Jankovic, J.2    Shannon, K.M.3    Tsui, J.4    Swenson, M.5    Leurgans, S.6
  • 11
    • 0030842423 scopus 로고    scopus 로고
    • Human response to botulinum toxin injection: type B compared with type A
    • Sloop R.R., Cole B.A., Escutin R.O. Human response to botulinum toxin injection: type B compared with type A. Neurology 1997, 49:189-194.
    • (1997) Neurology , vol.49 , pp. 189-194
    • Sloop, R.R.1    Cole, B.A.2    Escutin, R.O.3
  • 12
    • 9244247668 scopus 로고    scopus 로고
    • Antibody-induced failure of botulinum toxin type B therapy in de novo patients
    • Dressler D., Bigalke H. Antibody-induced failure of botulinum toxin type B therapy in de novo patients. Eur Neurol 2004, 52:132-135.
    • (2004) Eur Neurol , vol.52 , pp. 132-135
    • Dressler, D.1    Bigalke, H.2
  • 13
    • 0030472583 scopus 로고    scopus 로고
    • Mapping of the antibody-binding regions on botulinum neurotoxin H-chain domain 855-1296 with antitoxin antibodies from three host species
    • Atassi M.Z., Dolimbek B.Z., Hayakari M., Middlebrook J.L., Whitney B., Oshima M. Mapping of the antibody-binding regions on botulinum neurotoxin H-chain domain 855-1296 with antitoxin antibodies from three host species. J Protein Chem 1996, 15:691-700.
    • (1996) J Protein Chem , vol.15 , pp. 691-700
    • Atassi, M.Z.1    Dolimbek, B.Z.2    Hayakari, M.3    Middlebrook, J.L.4    Whitney, B.5    Oshima, M.6
  • 14
    • 4143121923 scopus 로고    scopus 로고
    • Mapping of the antibody-binding regions on the HN-domain (residues 449-859) of botulinum neurotoxin A with antitoxin antibodies from four host species. Full profile of the continuous antigenic regions of the H-chain of botulinum neurotoxin A
    • Atassi M.Z., Dolimbek B.Z. Mapping of the antibody-binding regions on the HN-domain (residues 449-859) of botulinum neurotoxin A with antitoxin antibodies from four host species. Full profile of the continuous antigenic regions of the H-chain of botulinum neurotoxin A. Protein J 2004, 23:39-52.
    • (2004) Protein J , vol.23 , pp. 39-52
    • Atassi, M.Z.1    Dolimbek, B.Z.2
  • 15
    • 18744383047 scopus 로고    scopus 로고
    • Mapping of the antibody and T cell recognition profiles of the HN domain (residues 449-859) of the heavy chain of botulinum neurotoxin A in two high-responder mouse strains
    • Dolimbek G.S., Dolimbek B.Z., Aoki K.R., Atassi M.Z. Mapping of the antibody and T cell recognition profiles of the HN domain (residues 449-859) of the heavy chain of botulinum neurotoxin A in two high-responder mouse strains. Immunol Invest 2005, 34:119-142.
    • (2005) Immunol Invest , vol.34 , pp. 119-142
    • Dolimbek, G.S.1    Dolimbek, B.Z.2    Aoki, K.R.3    Atassi, M.Z.4
  • 16
    • 38049061520 scopus 로고    scopus 로고
    • Molecular bases of protective immune responses against botulinum neurotoxin A-how antitoxin antibodies block its action
    • Atassi M.Z., Dolimbek B.Z., Steward L.E., Aoki K.R. Molecular bases of protective immune responses against botulinum neurotoxin A-how antitoxin antibodies block its action. Crit Rev Immunol 2007, 27:319-341.
    • (2007) Crit Rev Immunol , vol.27 , pp. 319-341
    • Atassi, M.Z.1    Dolimbek, B.Z.2    Steward, L.E.3    Aoki, K.R.4
  • 17
    • 77956264342 scopus 로고    scopus 로고
    • Inhibition of botulinum neurotoxin A toxic action in vivo by synthetic synaptosome- and blocking antibody-binding regions
    • Atassi M.Z., Dolimbek B.Z., Steward L.E., Aoki K.R. Inhibition of botulinum neurotoxin A toxic action in vivo by synthetic synaptosome- and blocking antibody-binding regions. Protein J 2010, 29:320-327.
    • (2010) Protein J , vol.29 , pp. 320-327
    • Atassi, M.Z.1    Dolimbek, B.Z.2    Steward, L.E.3    Aoki, K.R.4
  • 18
    • 33748777674 scopus 로고    scopus 로고
    • Mapping of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT/A
    • Dolimbek B.Z., Aoki K.R., Steward L.E., Jankovic J., Atassi M.Z. Mapping of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT/A. Mol Immunol 2007, 44:1029-1041.
    • (2007) Mol Immunol , vol.44 , pp. 1029-1041
    • Dolimbek, B.Z.1    Aoki, K.R.2    Steward, L.E.3    Jankovic, J.4    Atassi, M.Z.5
  • 19
    • 35548984968 scopus 로고    scopus 로고
    • Immune recognition of botulinum neurotoxin B: antibody-binding regions on the heavy chain of the toxin
    • Dolimbek B.Z., Steward L.E., Aoki K.R., Atassi M.Z. Immune recognition of botulinum neurotoxin B: antibody-binding regions on the heavy chain of the toxin. Mol Immunol 2008, 45:910-924.
    • (2008) Mol Immunol , vol.45 , pp. 910-924
    • Dolimbek, B.Z.1    Steward, L.E.2    Aoki, K.R.3    Atassi, M.Z.4
  • 20
    • 79955541733 scopus 로고    scopus 로고
    • Regions of recognition by blocking antibodies on the light chain of BoNT/A. Antigenic structure of the entire toxin
    • Dolimbek B.Z., Steward L.E., Aoki K.R., Atassi M.Z. Regions of recognition by blocking antibodies on the light chain of BoNT/A. Antigenic structure of the entire toxin. Immunobiology 2010, 10.1016/j.imbio.2010.10.010.
    • (2010) Immunobiology
    • Dolimbek, B.Z.1    Steward, L.E.2    Aoki, K.R.3    Atassi, M.Z.4
  • 21
    • 16844363634 scopus 로고    scopus 로고
    • Mapping of the synaptosome-binding regions on the heavy chain of botulinum neurotoxin A by synthetic overlapping peptides encompassing the entire chain
    • Maruta T., Dolimbek B.Z., Aoki K.R., Steward L.E., Atassi M.Z. Mapping of the synaptosome-binding regions on the heavy chain of botulinum neurotoxin A by synthetic overlapping peptides encompassing the entire chain. Protein J 2004, 23:539-552.
    • (2004) Protein J , vol.23 , pp. 539-552
    • Maruta, T.1    Dolimbek, B.Z.2    Aoki, K.R.3    Steward, L.E.4    Atassi, M.Z.5
  • 22
    • 33644509544 scopus 로고    scopus 로고
    • Inhibition by human sera of botulinum neurotoxin-A binding to synaptosomes: a new assay for blocking and non-blocking antibodies
    • Maruta T., Dolimbek B.Z., Aoki K.R., Atassi M.Z. Inhibition by human sera of botulinum neurotoxin-A binding to synaptosomes: a new assay for blocking and non-blocking antibodies. J Neurosci Methods 2006, 151:90-96.
    • (2006) J Neurosci Methods , vol.151 , pp. 90-96
    • Maruta, T.1    Dolimbek, B.Z.2    Aoki, K.R.3    Atassi, M.Z.4
  • 23
    • 0026687439 scopus 로고
    • Epitope-specific suppression of antibody response in experimental autoimmune myasthenia gravis by a monomethoxypolyethylene glycol conjugate of a myasthenogenic synthetic peptide
    • Atassi M.Z., Ruan K.H., Jinnai K., Oshima M., Ashizawa T. Epitope-specific suppression of antibody response in experimental autoimmune myasthenia gravis by a monomethoxypolyethylene glycol conjugate of a myasthenogenic synthetic peptide. Proc Natl Acad Sci USA 1992, 89:5852-5856.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5852-5856
    • Atassi, M.Z.1    Ruan, K.H.2    Jinnai, K.3    Oshima, M.4    Ashizawa, T.5
  • 24
    • 0026325265 scopus 로고
    • Synthesis of tolerogenic monomethoxypolyethylene glycol and polyvinyl alcohol conjugates of peptides
    • Atassi M.Z., Manshouri T. Synthesis of tolerogenic monomethoxypolyethylene glycol and polyvinyl alcohol conjugates of peptides. J Protein Chem 1991, 10:623-627.
    • (1991) J Protein Chem , vol.10 , pp. 623-627
    • Atassi, M.Z.1    Manshouri, T.2
  • 25
    • 0014772602 scopus 로고
    • Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
    • Kaiser E., Colescott R.L., Bossinger C.D., Cook P.I. Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal Biochem 1970, 34:595-598.
    • (1970) Anal Biochem , vol.34 , pp. 595-598
    • Kaiser, E.1    Colescott, R.L.2    Bossinger, C.D.3    Cook, P.I.4
  • 26
    • 0025032015 scopus 로고
    • Preparation and application of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminoethyl-3 5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions
    • Albericio F., Kneib-Cordonier N., Biancalana S., Gera L., Masada R.I., Hudson D., et al. Preparation and application of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminoethyl-3 5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions. J Org Chem 1990, 55:3730-3743.
    • (1990) J Org Chem , vol.55 , pp. 3730-3743
    • Albericio, F.1    Kneib-Cordonier, N.2    Biancalana, S.3    Gera, L.4    Masada, R.I.5    Hudson, D.6
  • 27
    • 0033901468 scopus 로고    scopus 로고
    • T cells of mice treated with mPEG-myasthenogenic peptide conjugate are involved in protection against EAMG by stimulating lower pathogenic antibody responses
    • Oshima M., Atassi M.Z. T cells of mice treated with mPEG-myasthenogenic peptide conjugate are involved in protection against EAMG by stimulating lower pathogenic antibody responses. Autoimmunity 2000, 32:45-55.
    • (2000) Autoimmunity , vol.32 , pp. 45-55
    • Oshima, M.1    Atassi, M.Z.2
  • 28
    • 0030266775 scopus 로고    scopus 로고
    • B-cell activation in vitro by helper T cells specific to region alpha 146-162 of Torpedo californica nicotinic acetylcholine receptor
    • Rosenberg J.S., Oshima M., Atassi M.Z. B-cell activation in vitro by helper T cells specific to region alpha 146-162 of Torpedo californica nicotinic acetylcholine receptor. J Immunol 1996, 157:3192-3199.
    • (1996) J Immunol , vol.157 , pp. 3192-3199
    • Rosenberg, J.S.1    Oshima, M.2    Atassi, M.Z.3
  • 29
    • 1842408338 scopus 로고    scopus 로고
    • Intersite helper function of T cells specific for a protein epitope that is not recognized by antibodies
    • Rosenberg J.S., Atassi M.Z. Intersite helper function of T cells specific for a protein epitope that is not recognized by antibodies. Immunol Invest 1997, 26:473-489.
    • (1997) Immunol Invest , vol.26 , pp. 473-489
    • Rosenberg, J.S.1    Atassi, M.Z.2
  • 30
    • 0031862123 scopus 로고    scopus 로고
    • B-cell activation in vitro by helper T cells specific to a protein region that is recognized both by T cells and by antibodies
    • Hamajima S., Atassi M.Z. B-cell activation in vitro by helper T cells specific to a protein region that is recognized both by T cells and by antibodies. Immunol Invest 1998, 27:121-134.
    • (1998) Immunol Invest , vol.27 , pp. 121-134
    • Hamajima, S.1    Atassi, M.Z.2
  • 31
    • 0042710491 scopus 로고    scopus 로고
    • Immunologic and other properties of therapeutic botulinum toxin serotypes
    • Lippincott Williams & Wilkins, Philadelphia, M.F. Brin, M. Hallett, J. Jankovic (Eds.)
    • Aoki K.R. Immunologic and other properties of therapeutic botulinum toxin serotypes. Scientific and therapeutic aspects of botulinum toxin, 2002, 103-113. Lippincott Williams & Wilkins, Philadelphia. M.F. Brin, M. Hallett, J. Jankovic (Eds.).
    • (2002) Scientific and therapeutic aspects of botulinum toxin, , pp. 103-113
    • Aoki, K.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.