Intensity-modulated radiotherapy for locally advanced non-small-cell lung cancer: A dose-escalation planning study

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 1, 2011, Pages 306-313

  Lievens, Yolande ^a   Nulens, An ^a   Gaber, Mousa Amr ^b   Defraene, Gilles ^a   De Wever, Walter ^a   Stroobants, Sigrid ^c   Van Den Heuvel, Frank ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b CAIRO UNIVERSITY   (Egypt)

^c ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Dose escalation; Intensity modulated radiotherapy; Locally advanced non small cell lung cancer; Normal tissue complication probability

Indexed keywords

ACUTE TOXICITY; CHEMORADIOTHERAPY; COLLAPSED CONES; DOSE CALCULATION; DOSE LIMITS; DOSE-ESCALATION; END-POINT CONSTRAINT; INTENSITY-MODULATED RADIOTHERAPY; LOW DOSE LEVELS; NON SMALL CELL LUNG CANCER; NORMAL TISSUE COMPLICATION PROBABILITIES; PENCIL BEAM ALGORITHMS; RADIOTHERAPY PLANNING; SPINAL CORDS; THREE-DIMENSIONAL CONFORMAL RADIOTHERAPY;

ALGORITHMS; BIOLOGICAL ORGANS; DISEASES; DOSIMETRY; POSITRON EMISSION TOMOGRAPHY; PROBABILITY; RADIOTHERAPY; THREE DIMENSIONAL; TISSUE; TOXICITY;

PHYSICAL THERAPY;

ADULT; AGED; ALGORITHM; ARTICLE; CLINICAL ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; DOSE CALCULATION; FEMALE; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LUNG NON SMALL CELL CANCER; MALE; PNEUMONIA; PRIORITY JOURNAL; PROBABILITY; RADIATION DOSE; SPINAL CORD; TREATMENT PLANNING;

ADENOCARCINOMA; ADULT; AGED; CARCINOMA, LARGE CELL; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; ESOPHAGUS; FEMALE; HEART; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; ORGANS AT RISK; PROBABILITY; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RADIOTHERAPY, INTENSITY-MODULATED; SPINAL CORD;

EID: 79954424671     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.06.025     Document Type: Article

References (37)

1. J.P. van Meerbeeck, G.W. Kramer, and P.E. van Schil Randomized controlled trial of resection versus radiotherapy after induction chemotherapy in stage IIIA-N2 NSCLC J Natl Cancer Inst 99 2007 442 450 (Pubitemid 47073567)
2. J. Vansteenkiste, D. Betticher, and W. Eberhardt Randomized controlled trial of resection versus radiotherapy after induction chemotherapy in stage IIIA-N2 NSCLC J Thor Oncol 2 2007 684 685 (Pubitemid 47357519)
3. N.P. Rowell, and N.P. O'Rourke Concurrent chemoradiotherapy in NSCLC Cochrane Database Syst Rev 18 2004 CD002140
4. A. Aupérin, C. Le Péchoux, and E. Rolland Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer J Clin Oncol 28 13 2010 2181 2190
5. M.K. Gould, W.G. Kuschner, and C.E. Rydzak Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with NSCLC: A meta-analysis Ann Intern Med 139 2003 879 892
6. U. Nestle, S. Kremp, and A. Grosu Practical integration of [18F]-FDG-PET and PET-CT in the planning of radiotherapy for NSCLC: The technical basis, ICRU-target volumes, problems, perspectives Radiother Oncol 81 2006 209 225 (Pubitemid 44780785)
7. 18F-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET) lymph node staging on the radiation treatment volumes in patients with NSCLC Radiother Oncol 55 2000 317 324 (Pubitemid 30408377)
8. A. Hoge Klopp, J.Y. Chang, and S.L. Tucker Intrathoracic patterns of failure for NSCLC with positron-emission tomography/computed tomography-defined target delineation Int J Radiat Oncol Biol Phys 69 2007 1409 1416 (Pubitemid 350116417)
9. K.E. Rosenzweig, S. Sura, and A. Jackson Involved-field radiation therapy for inoperable NSCLC J Clin Oncol 25 2007 5557 5561
10. S. Senan, D. De Ruysscher, and P. Giraud Literature-based recommendations for treatment planning and execution in high-dose radiotherapy for lung cancer Radiother Oncol 71 2004 139 146 (Pubitemid 38521181)
11. F.-M. Kong, C. Pan, and A. Eisbruch Physical models and simpler dosimetric descriptors of radiation late toxicity Semin Radiat Oncol 17 2007 108 120 (Pubitemid 46467381)
12. C.F. Mountain, and C.M. Dresler Regional lymph node classification for lung cancer staging Chest 111 1997 1718 1723 (Pubitemid 27260108)
13. Y. Seppenwoolde, J.V. Lebesque, and K. De Jaeger Comparing different NTCP models that predict the incidence of radiation pneumonitis Int J Radiat Oncol Biol Phys 55 2003 724 735 (Pubitemid 36170012)
14. O. Chapet, E. Thomas, and M.L. Kessler Esophagus sparing with IMRT in lung tumor irradiation: an EUD-based optimization technique Int J Radiat Oncol Biol Phys 63 2005 179 187 (Pubitemid 41583556)
15. O. Chapet, F.-M. Kong, and J.S. Lee Normal tissue complication probability modeling for acute esophagitis in patients treated with conformal radiation therapy for NSCLC Radiother Oncol 77 2005 176 181 (Pubitemid 41682384)
16. I.A. Grills, D. Yan, and A.A. Martinez Potential for reduced toxicity and dose escalation in the treatment of inoperable NSCLC: A comparison of IMRT, 3D-CRT, and elective nodal irradiation Int J Radiat Oncol Biol Phys 57 2003 875 890
17. M. Schwarz, M. Alber, and J.V. Lebesque Dose heterogeneity in the target volume and IMRT to escalated the dose in the treatment of NSCLC Int J Radiat Oncol Biol Phys 62 2005 561 570 (Pubitemid 40704476)
18. H. Murshed, H.L. Liu, and Z. Liao Dose and volume reduction for normal lung using IMRT for advanced-stage NSCLC Int J Radiat Oncol Biol Phys 58 2004 1258 1267
19. J.A. Christian, J.L. Bedford, and S. Webb Comparison of inverse-planned three-dimensional and IMRT for NSCLC Int J Radiat Oncol Biol Phys 67 2007 735 741
20. S. Derycke, B. Van Duyse, and W. De Gersem Non-coplanar beam intensity modulation allows large dose escalation in stage III lung cancer Radiother Oncol 45 1997 253 261 (Pubitemid 27515176)
21. J. St-Hilaire, C. Sévigny, and F. Beaulieu Dose escalation in the radiotherapy of NSCLC with aperture-based intensity modulation and photon beam energy optimization for non-preselected patients Radiother Oncol 91 2009 342 348
22. H.L. Liu, X. Wang, and L. Dong Feasibility of sparing lung and other thoracic structures with IMRT for NSCLC Int J Radiat Oncol Biol Phys 58 2004 1268 1279
23. O. Chapet, B.A. Fraass, and R.K. ten Haken Multiple fields may offer better esophagus sparing without increased probability of lung toxicity in optimized IMRT of lung tumors Int J Radiat Oncol Biol Phys 65 2006 255 265
24. Y. Xiao, M. Werner-Wasik, and D. Michalski Comparison of three IMRT inverse planning techniques that allow for partial esophagus sparing in patients receiving thoracic radiation therapy for lung cancer Med Dosim 29 2004 210 216 (Pubitemid 39486010)
25. J. Rose, G. Rodrigues, and B. Yaremko Systematic review of dose-volume parameters in the prediction of esophagitis in thoracic radiotherapy Radiother Oncol 91 2009 282 287
26. C.L. Holloway, D. Robinson, and B. Murray Results of a phase I study to dose escalate using IMRT guided by combined PET/CT imaging with induction chemotherapy for patients with NSCLC Radiother Oncol 73 2004 285 287 (Pubitemid 39601075)
27. S.S. Yom, Z. Liao, and H.H. Liu Initial evaluation of treatment-related pneumonitis in advanced-stage NSCLC patients treated with concurrent chemotherapy and IMRT Int J Radiat Oncol Biol Phys 68 2007 94 102 (Pubitemid 46589835)
28. S. Sura, V. Gupta, and E. Yorke IMRT for inoperable NSCLC: The Memorial Sloan-Kettering Cancer Center (MSKCC) experience Radiother Oncol 87 2008 17 23
29. Z.X. Liao, R.R. Komaki, and H.D. Thames Influence of technological advances on outcomes in patients with unresectable LA-NSCLC receiving concomitant chemoradiotherapy Int J Radiat Oncol Biol Phys 76 2010 775 781
30. T. Bortfeld, K. Jokivarsi, and M. Goitein Effects of intra-fraction motion on IMRT dose delivery: Statistical analysis and simulation Phys Med Biol 47 2002 2203 2220 (Pubitemid 34812201)
31. C.S. Chui, E. Yorke, and L. Hong The effects of intra-fraction organ motion on the delivery of intensity-modulated field with a multileaf collimator Med Phys 30 2003 1736 1746 (Pubitemid 36885791)
32. B. Reitz, D.S. Parda, and A. Colonias Investigation of simple IMRT delivery techniques for NSCLC patients with respiratory motion using 4DCT Med Dosim 34 2009 158 169
33. A.M. Allen, M. Czerminska, and P.A. Jänne Fatal pneumonitis associated with IMRT for mesothelioma Int J Radiat Oncol Biol Phys 65 2006 640 645
34. S.E. Davidson, R.A. Popple, and G.S. Ibbott Technical note: Heterogeneity dose calculation accuracy in IMRT: Study of five commercial treatment planning systems using an anthropomorphic thorax phantom Med Phys 35 12 2008 5434 5439
35. C. Bragg, K. Wingate, and J. Conway Clinical implications of the anisotropic analytical algorithm for IMRT treatment planning and verification Radiother Oncol 86 2008 276 284
36. E. Sterpin, M. Tomsey, and B. Desmedt Monte Carlo evaluation of AAA treatment planning algorithm in a heterogeneous multilayer phantom and IMRT clinical treatments for an Elekta SL25 linear accelerator Med Phys 34 5 2007 1665 1677 (Pubitemid 46669161)
37. W. De Neve, and C. De Wachter Lethal pneumonitis in a phase I study of chemotherapy and IMRT for NSCLC: The need to investigate the accuracy of dose computation Radiother Oncol 75 2005 246 247 (Pubitemid 40805257)