메뉴 건너뛰기




Volumn 158, Issue 5, 2011, Pages 740-744

A common variant in the PNPLA3 gene is a risk factor for non-alcoholic fatty liver disease in obese Taiwanese children

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; MEMBRANE PROTEIN; PROTEIN PNPLA 3; UNCLASSIFIED DRUG;

EID: 79954421951     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2010.11.016     Document Type: Article
Times cited : (83)

References (30)
  • 1
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • DOI 10.1016/S0016-5085(99)70506-8
    • C.A. Matteoni, Z.M. Younossi, T. Gramlich, N. Boparai, Y.C. Liu, and A.J. McCullough Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity Gastroenterology 116 1999 1413 1419 (Pubitemid 29258890)
    • (1999) Gastroenterology , vol.116 , Issue.6 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3    Boparai, N.4    Yao Chang Liu5    McCullough, A.J.6
  • 4
    • 0242361733 scopus 로고    scopus 로고
    • Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease
    • DOI 10.1067/S0022-3476(03)00325-1
    • J.B. Schwimmer, R. Deutsch, J.B. Rauch, C. Behling, R. Newbury, and J.E. Lavine Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease J Pediatr 143 2003 500 505 (Pubitemid 37352510)
    • (2003) Journal of Pediatrics , vol.143 , Issue.4 , pp. 500-505
    • Schwimmer, J.B.1    Deutsch, R.2    Rauch, J.B.3    Behling, C.4    Newbury, R.5    Lavine, J.E.6
  • 6
    • 47749134925 scopus 로고    scopus 로고
    • Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)
    • M. Yoneda, K. Hotta, Y. Nozaki, H. Endo, T. Uchiyama, and H. Mawatari Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD) BMC Gastroenterol 8 2008 27
    • (2008) BMC Gastroenterol , vol.8 , pp. 27
    • Yoneda, M.1    Hotta, K.2    Nozaki, Y.3    Endo, H.4    Uchiyama, T.5    Mawatari, H.6
  • 7
    • 33746131326 scopus 로고    scopus 로고
    • Increased risk of NASH in patients carrying the C(-159)T polymorphism in the CD14 gene promoter region [9]
    • DOI 10.1136/gut.2006.093336
    • P. Brun, I. Castagliuolo, A.R. Floreani, A. Buda, L. Blasone, and G. Palu Increased risk of NASH in patients carrying the C(-159)T polymorphism in the CD14 gene promoter region Gut 55 2006 1212 (Pubitemid 44085699)
    • (2006) Gut , vol.55 , Issue.8 , pp. 1212
    • Brun, P.1    Castagliuolo, I.2    Floreani, A.R.3    Buda, A.4    Blasone, L.5    Palu, G.6    Martines, D.7
  • 8
    • 34247554214 scopus 로고    scopus 로고
    • Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis
    • DOI 10.1016/j.jhep.2007.01.028, PII S0168827807000761
    • K. Tokushige, M. Takakura, N. Tsuchiya-Matsushita, M. Taniai, E. Hashimoto, and K. Shiratori Influence of TNF gene polymorphisms in Japanese patients with NASH and simple steatosis J Hepatol 46 2007 1104 1110 (Pubitemid 46669735)
    • (2007) Journal of Hepatology , vol.46 , Issue.6 , pp. 1104-1110
    • Tokushige, K.1    Takakura, M.2    Tsuchiya-Matsushita, N.3    Taniai, M.4    Hashimoto, E.5    Shiratori, K.6
  • 9
    • 0348134731 scopus 로고    scopus 로고
    • Pro-fibrotic polymorphisms predictive of advanced liver fibrosis in the severely obese
    • DOI 10.1016/S0168-8278(03)00459-8
    • J.B. Dixon, P.S. Bhathal, J.R. Jonsson, A.F. Dixon, E.E. Powell, and P.E. O'Brien Pro-fibrotic polymorphisms predictive of advanced liver fibrosis in the severely obese J Hepatol 39 2003 967 971 (Pubitemid 37523767)
    • (2003) Journal of Hepatology , vol.39 , Issue.6 , pp. 967-971
    • Dixon, J.B.1    Bhathal, P.S.2    Jonsson, J.R.3    Dixon, A.F.4    Powell, E.E.5    O'Brien, P.E.6
  • 10
    • 46049097550 scopus 로고    scopus 로고
    • The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease
    • L. Miele, G. Beale, G. Patman, V. Nobili, J. Leathart, and A. Grieco The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease Gastroenterology 135 2008 282 291
    • (2008) Gastroenterology , vol.135 , pp. 282-291
    • Miele, L.1    Beale, G.2    Patman, G.3    Nobili, V.4    Leathart, J.5    Grieco, A.6
  • 11
    • 71949122207 scopus 로고    scopus 로고
    • Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease
    • Y.C. Lin, P.F. Chang, F.C. Hu, M.H. Chang, and Y.H. Ni Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease Pediatrics 124 2009 e1221 e1227
    • (2009) Pediatrics , vol.124
    • Lin, Y.C.1    Chang, P.F.2    Hu, F.C.3    Chang, M.H.4    Ni, Y.H.5
  • 12
    • 56749096610 scopus 로고    scopus 로고
    • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
    • S. Romeo, J. Kozlitina, C. Xing, A. Pertsemlidis, D. Cox, and L.A. Pennacchio Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease Nat Genet 40 2008 1461 1465
    • (2008) Nat Genet , vol.40 , pp. 1461-1465
    • Romeo, S.1    Kozlitina, J.2    Xing, C.3    Pertsemlidis, A.4    Cox, D.5    Pennacchio, L.A.6
  • 14
    • 77949895032 scopus 로고    scopus 로고
    • A sequence variation (I148M) in PNPlA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
    • S. He, C. McPhaul, J.Z. Li, R. Garuti, L.N. Kinch, and N.V. Grishin A sequence variation (I148M) in PNPlA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis J Biol Chem 285 2010 6706 6715
    • (2010) J Biol Chem , vol.285 , pp. 6706-6715
    • He, S.1    McPhaul, C.2    Li, J.Z.3    Garuti, R.4    Kinch, L.N.5    Grishin, N.V.6
  • 15
    • 53049090077 scopus 로고    scopus 로고
    • Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
    • X. Yuan, D. Waterworth, J.R. Perry, N. Lim, K. Song, and J.C. Chambers Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes Am J Hum Genet 83 2008 520 528
    • (2008) Am J Hum Genet , vol.83 , pp. 520-528
    • Yuan, X.1    Waterworth, D.2    Perry, J.R.3    Lim, N.4    Song, K.5    Chambers, J.C.6
  • 16
    • 67349174005 scopus 로고    scopus 로고
    • A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans
    • A. Kotronen, L.E. Johansson, L.M. Johansson, C. Roos, J. Westerbacka, and A. Hamsten A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans Diabetologia 52 2009 1056 1060
    • (2009) Diabetologia , vol.52 , pp. 1056-1060
    • Kotronen, A.1    Johansson, L.E.2    Johansson, L.M.3    Roos, C.4    Westerbacka, J.5    Hamsten, A.6
  • 17
    • 69249111667 scopus 로고    scopus 로고
    • A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
    • S. Sookoian, G.O. Castano, A.L. Burgueno, T.F. Gianotti, M.S. Rosselli, and C.J. Pirola A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity J Lipid Res 50 2009 2111 2116
    • (2009) J Lipid Res , vol.50 , pp. 2111-2116
    • Sookoian, S.1    Castano, G.O.2    Burgueno, A.L.3    Gianotti, T.F.4    Rosselli, M.S.5    Pirola, C.J.6
  • 19
    • 70350550096 scopus 로고    scopus 로고
    • Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene
    • K. Kantartzis, A. Peter, F. Machicao, J. Machann, S. Wagner, and I. Konigsrainer Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene Diabetes 58 2009 2616 2623
    • (2009) Diabetes , vol.58 , pp. 2616-2623
    • Kantartzis, K.1    Peter, A.2    MacHicao, F.3    MacHann, J.4    Wagner, S.5    Konigsrainer, I.6
  • 20
    • 74249093842 scopus 로고    scopus 로고
    • Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent
    • S. Romeo, F. Sentinelli, S. Dash, G.S. Yeo, D.B. Savage, and F. Leonetti Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent Int J Obes 34 2010 190 194
    • (2010) Int J Obes , vol.34 , pp. 190-194
    • Romeo, S.1    Sentinelli, F.2    Dash, S.3    Yeo, G.S.4    Savage, D.B.5    Leonetti, F.6
  • 21
    • 77957936457 scopus 로고    scopus 로고
    • I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease
    • L. Valenti, A. Alisi, E. Galmozzi, A. Bartuli, B. Del Menico, and A. Alterio I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease Hepatology 52 2010 1274 1280
    • (2010) Hepatology , vol.52 , pp. 1274-1280
    • Valenti, L.1    Alisi, A.2    Galmozzi, E.3    Bartuli, A.4    Del Menico, B.5    Alterio, A.6
  • 22
    • 77955308935 scopus 로고    scopus 로고
    • The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life
    • S. Romeo, F. Sentinelli, V.M. Cambuli, M. Incani, T. Congiu, and V. Matta The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life J Hepatol 53 2010 335 338
    • (2010) J Hepatol , vol.53 , pp. 335-338
    • Romeo, S.1    Sentinelli, F.2    Cambuli, V.M.3    Incani, M.4    Congiu, T.5    Matta, V.6
  • 23
    • 77952783848 scopus 로고    scopus 로고
    • New growth charts for Taiwanese children and adolescents based on World Health Organization standards and health-related physical fitness
    • W. Chen, and M.H. Chang New growth charts for Taiwanese children and adolescents based on World Health Organization standards and health-related physical fitness Pediatr Neonatol 51 2010 69 79
    • (2010) Pediatr Neonatol , vol.51 , pp. 69-79
    • Chen, W.1    Chang, M.H.2
  • 24
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • DOI 10.1007/BF00280883
    • D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419 (Pubitemid 15018832)
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 27
    • 16444367799 scopus 로고    scopus 로고
    • Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents
    • J.B. Schwimmer, N. McGreal, R. Deutsch, M.J. Finegold, and J.E. Lavine Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents Pediatrics 115 2005 e561 e565
    • (2005) Pediatrics , vol.115
    • Schwimmer, J.B.1    McGreal, N.2    Deutsch, R.3    Finegold, M.J.4    Lavine, J.E.5
  • 28
    • 79954422561 scopus 로고    scopus 로고
    • dbSNP accession: ss48413901 (dbSNP build ID: 37.1) AccessedonSep2
    • Database of Single Nucleotide Polymorphisms. dbSNP accession: ss48413901 (dbSNP build ID: 37.1). Available from: http://www.ncbi.nlm.nih.gov/projects/ SNP/snp-ss.cgi?ss=ss48413901. Accessed on Sep 2, 2010.
    • (2010) Database of Single Nucleotide Polymorphisms
  • 29
    • 55149115873 scopus 로고    scopus 로고
    • Placebo in nonalcoholic steatohepatitis: Insight into natural history and implications for future clinical trials
    • R. Loomba, R. Wesley, F. Pucino, T.J. Liang, D.E. Kleiner, and J.E. Lavine Placebo in nonalcoholic steatohepatitis: insight into natural history and implications for future clinical trials Clin Gastroenterol Hepatol 6 2008 1243 1248
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1243-1248
    • Loomba, R.1    Wesley, R.2    Pucino, F.3    Liang, T.J.4    Kleiner, D.E.5    Lavine, J.E.6
  • 30
    • 34249682613 scopus 로고    scopus 로고
    • Role of Radiologic Modalities in the Management of Non-alcoholic Steatohepatitis
    • DOI 10.1016/j.cld.2007.02.014, PII S1089326107000128, Non-Alcoholic Steatohepatitis and Non-Alcoholic Fatty Liver Disease
    • P. Charatcharoenwitthaya, and K.D. Lindor Role of radiologic modalities in the management of non-alcoholic steatohepatitis Clin Liver Dis 11 2007 37 54 (Pubitemid 46829975)
    • (2007) Clinics in Liver Disease , vol.11 , Issue.1 , pp. 37-54
    • Charatcharoenwitthaya, P.1    Lindor, K.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.