Postnatal decrease in circulating insulin-like growth factor-I and low brain volumes in very preterm infants

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 4, 2011, Pages 1129-1135

  Hansen Pupp, Ingrid ^a   Hövel, Holger ^a   Hellström, Ann ^b   Hellström Westas, Lena ^c   Löfqvist, Chatarina ^b   Larsson, Elna Marie ^d   Lazeyras, Francois ^e   Fellman, Vineta ^a,g   Hüppi, Petra S ^f   Ley, David ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c Departments of Women's and Children's Health   (Sweden)

^d UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^e University of Lausanne   (Switzerland)

^f GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^g UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; HYDROCORTISONE; INSULIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ANATOMICAL VARIATION; ARTICLE; BIRTH WEIGHT; BLOOD SAMPLING; BRAIN DEVELOPMENT; BRAIN GROWTH; BRAIN SIZE; CALORIC INTAKE; CEREBELLUM; CEREBROSPINAL FLUID; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; GRAY MATTER; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; HYPOTENSION; INFANT; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; POSTNATAL DEVELOPMENT; PREMATURITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN INTAKE; WHITE MATTER;

BRAIN; COHORT STUDIES; DOWN-REGULATION; FEMALE; GESTATIONAL AGE; HUMANS; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MAGNETIC RESONANCE IMAGING; MALE; ORGAN SIZE;

EID: 79953906297     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-2440     Document Type: Article

References (40)

1. Laptook AR, O'Shea TM, Shankaran S, Bhaskar B 2005 Adverse neurodevelopmental outcomes among extremely low birth weight infants with a normal head ultrasound: Prevalence and antecedents. Pediatrics 115:673-680 (Pubitemid 43373028)
2. Inder TE, Warfield SK,WangH,Hüppi PS, Volpe JJ 2005 Abnormal cerebral structure is present at term in premature infants. Pediatrics 115:286-294 (Pubitemid 43193809)
3. Thompson DK, Warfield SK, Carlin JB, Pavlovic M, Wang HX, BearM,Kean MJ, DoyleLW,Egan GF, InderTE2007 Perinatal risk factors altering regional brain structure in the preterm infant. Brain 130:667-677 (Pubitemid 46410727)
4. Cheong JL, Hunt RW, Anderson PJ, Howard K, Thompson DK, Wang HX, Bear MJ, Inder TE, Doyle LW 2008 Head growth in preterm infants: Correlation with magnetic resonance imaging and neurodevelopmental outcome. Pediatrics 121:e1534-e1540
5. Latal-Hajnal B, von Siebenthal K, Kovari H, Bucher HU, LargoRH 2003 Postnatal growth in VLBW infants: Significant association with neurodevelopmental outcome. J Pediatr 143:163-170 (Pubitemid 37082946)
6. Löfqvist C, EngströmE, Sigurdsson J, Hård AL, Niklasson A, Ewald U, Holmström G, Smith LE, Hellström A 2006 Postnatal head growth deficit among premature infants parallels retinopathy of prematurity and insulin-like growth factor-1 deficit. Pediatrics 117: 1930-1938 (Pubitemid 46071236)
7. Langford K, Nicolaides K, Miell JP 1998 Maternal and fetal insulinlike growth factors and their binding proteins in the second and third trimesters of human pregnancy. Hum Reprod 13:1389-1393 (Pubitemid 28279201)
8. Guan J, Bennet L, George S, Wu D, Waldvogel HJ, Gluckman PD, Faull RL, Crosier PS, Gunn AJ 2001 Insulin-like growth factor-1 reduces postischemic white matter injury in fetal sheep. J Cereb Blood Flow Metab 21:493-502 (Pubitemid 32422869)
9. Popken GJ, Hodge RD, Ye P, Zhang J, Ng W, O'Kusky JR, D'Ercole AJ 2004 In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system. Eur J Neurosci 19:2056-2068 (Pubitemid 38582195)
10. Ye P, Kollias G, D'Ercole AJ 2007 Insulin-like growth factor-I ameliorates demyelination induced by tumor necrosis factor-α in transgenic mice. J Neurosci Res 85:712-722 (Pubitemid 46426070)
11. Lofqvist C, Chen J, Connor KM, Smith AC, Aderman CM, Liu N, Pintar JE, Ludwig T, Hellstrom A, Smith LE 2007 IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth. Proc Natl Acad Sci USA 104:10589-10594 (Pubitemid 47185709)
12. Hansen-Pupp I, Hellström-Westas L, Cilio CM, Andersson S, Fellman V, Ley D 2007 Inflammation at birth and the insulin-like growth factor system in very preterm infants. Acta Paediatr 96:830-836 (Pubitemid 46846893)
13. Hellström A, Engström E, Hård AL, Albertsson-Wikland K, Carlsson B, Niklasson A, Löfqvist C, Svensson E, Holm S, Ewald U, Holmström G, Smith LE 2003 Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth. Pediatrics 112:1016-1020 (Pubitemid 37339551)
14. Kajantie E, Dunkel L, Rutanen EM, Seppä lä M, Koistinen R, Sarnesto A, Andersson S 2002 IGF-I, IGF binding protein (IGFBP)-3, phosphoisoforms of IGFBP-1, and postnatal growth in very low birth weight infants. J Clin Endocrinol Metab 87:2171-2179 (Pubitemid 34521505)
15. Ohkawa N, Shoji H, Kitamura T, Suganuma H, Yoshikawa N, Suzuki M, Lee T, Hisata K, Shimizu T 2010 IGF-I, leptin and active ghrelin levels in very low birth weight infants during the first 8 weeks of life. Acta Paediatr 99:37-41
16. Marsá l K, Persson PH, Larsen T, Lilja H, Selbing A, Sultan B 1996 Intrauterine growth curves based on ultrasonically estimated foetal weights. Acta Paediatr 85:843-848 (Pubitemid 26267023)
17. Blum WF, Breier BH 1994 Radioimmunoassays for IGFs and IGFBPs. Growth Regul 4(Suppl 1):11-19
18. Warfield SK, Kaus M, Jolesz FA, Kikinis R 2000 Adaptive, template moderated, spatially varying statistical classification. Med Image Anal 4:43-55
19. Gluckman PD, Pinal CS 2003 Regulation of fetal growth by the somatotrophic axis. J Nutr 133:1741S-1746S (Pubitemid 36548684)
20. Beck KD, Powell-Braxton L, Widmer HR, Valverde J, Hefti F 1995 Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumincontaining neurons. Neuron 14:717-730
21. Woods KA, Camacho-Hübner C, Savage MO, Clark AJ 1996 Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med 335:1363-1367 (Pubitemid 26360455)
22. Carson MJ, Behringer RR, Brinster RL, McMorris FA 1993 Insulinlike growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron 10:729-740 (Pubitemid 23127975)
23. Chrysis D, Calikoglu AS,YeP, D'Ercole AJ 2001 Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. J Neurosci 21:1481-1489 (Pubitemid 32184293)
24. O'Kusky JR, Ye P, D'Ercole AJ 2000 Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. J Neurosci 20:8435-8442
25. Lee KH, Calikoglu AS, Ye P, D'Ercole AJ 1999 Insulin-like growth factor-I (IGF-I) ameliorates and IGF binding protein-1 (IGFBP-1) exacerbates the effects of undernutrition on brain growth during early postnatal life: Studies in IGF-I and IGFBP-1 transgenic mice. Pediatr Res 45:331-336 (Pubitemid 29157763)
26. Engström E, Niklasson A, Wikland KA, Ewald U, HellströmA2005 The role of maternal factors, postnatal nutrition, weight gain, and gender in regulation of serum IGF-I among preterm infants. Pediatr Res 57:605-610 (Pubitemid 40389352)
27. Johansson PA, DziegielewskaKM,Liddelow SA, SaundersNR2008 The blood-CSF barrier explained: When development is not immaturity. Bioessays 30:237-248 (Pubitemid 351341128)
28. Carro E, Nuñez A, Busiguina S, Torres-Aleman I 2000 Circulating insulin-like growth factor I mediates effects of exercise on the brain. J Neurosci 20:2926-2933 (Pubitemid 30220318)
29. Reinhardt RR, BondyCA1994 Insulin-like growth factors cross the blood-brain barrier. Endocrinology 135:1753-1761 (Pubitemid 24363863)
30. Allin MP, Salaria S, Nosarti C, Wyatt J, Rifkin L, MurrayRM2005 Vermis and lateral lobes of the cerebellum in adolescents born very preterm. Neuroreport 16:1821-1824 (Pubitemid 41547054)
31. Limperopoulos C, Soul JS, Gauvreau K, Huppi PS, Warfield SK, Bassan H, Robertson RL, Volpe JJ, du Plessis AJ 2005 Late gestation cerebellar growth is rapid and impeded by premature birth. Pediatrics 115:688-695 (Pubitemid 43373030)
32. Shah DK, Anderson PJ, Carlin JB, Pavlovic M, Howard K, Thompson DK, Warfield SK, Inder TE 2006 Reduction in cerebellar volumes in preterm infants: Relationship to white matter injury and neurodevelopment at two years of age. Pediatr Res 60:97-102 (Pubitemid 44297621)
33. LinsemanDA,Phelps RA, Bouchard RJ, Le SS, Laessig TA,McClure ML, Heidenreich KA 2002 Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. J Neurosci 22:9287-9297 (Pubitemid 35356172)
34. Ye P, Xing Y, Dai Z, D'Ercole AJ 1996 In vivo actions of insulin-like growth factor-I (IGF-I) on cerebellum development in transgenic mice: Evidence that IGF-I increases proliferation of granule cell progenitors. Brain Res Dev Brain Res 95:44-54 (Pubitemid 26259821)
35. Lodygensky GA, Seghier ML, Warfield SK, Tolsa CB, Sizonenko S, Lazeyras F, Hüppi PS 2008 Intrauterine growth restriction affects the preterm infant's hippocampus. Pediatr Res 63:438-443 (Pubitemid 351450594)
36. Tolsa CB, Zimine S, Warfield SK, Freschi M, Sancho Rossignol A, Lazeyras F, Hanquinet S, Pfizenmaier M, Huppi PS 2004 Early alteration of structural and functional brain development in premature infants born with intrauterine growth restriction. Pediatr Res 56:132-138 (Pubitemid 38808554)
37. Mallard C, Loeliger M, Copolov D, Rees S 2000 Reduced number of neurons in the hippocampus and the cerebellum in the postnatal guinea-pig following intrauterine growth-restriction. Neuroscience 100:327-333
38. Ajayi-Obe M, Saeed N, Cowan FM, Rutherford MA, Edwards AD 2000 Reduced development of cerebral cortex in extremely preterm infants. Lancet 356:1162-1163
39. Vasileiadis GT, Gelman N, Han VK, Williams LA, Mann R, Bureau Y, Thompson RT 2004 Uncomplicated intraventricular hemorrhage is followed by reduced cortical volume at near-term age. Pediatrics 114:e367-372 (Pubitemid 41529504)
40. Lin S, Fan LW, Rhodes PG, CaiZ2009 Intranasal administration of IGF-1 attenuates hypoxic-ischemic brain injury in neonatal rats. Exp Neurol 217:361-370