Combined influences of chromatic aberration and scattering in depth-resolved two-photon fluorescence endospectroscopy

Biomedical Optics Express

Volumn 1, Issue 4, 2010, Pages 1234-1243

  Wu, Yicong ^a   Li, Xingde ^a  

^a Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EXPERIMENTS; FLUORESCENCE; MONTE CARLO METHODS; PHOTONS; POLYSTYRENES; SCATTERING; TISSUE; TITANIUM DIOXIDE;

CHROMATIC ABERRATION; COLLECTION EFFICIENCY; DEPTH-RESOLVED; FLUORESCENCE SIGNALS; GELATIN PHANTOMS; GRADIENT-INDEX LENS; IMAGING DEPTH; LINE SHAPE; MONTE CARLO SIMULATION; OBJECTIVE LENS; OUT-OF-FOCUS; POLYSTYRENE BEADS; SCATTERING MEDIA; SCATTERING MEDIUM; SPECTRAL DISTORTIONS; SPECTRAL INTENSITY; TIO; TWO PHOTON FLUORESCENCE;

ABERRATIONS;

EID: 79953905273     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.1.001234     Document Type: Article

References (21)

1. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy, " Science 248(4951), 73-76 (1990).
2. Y. C. Guo, P. P. Ho, H. Savage, D. Harris, P. Sacks, S. Schantz, F. Liu, N. Zhadin, and R. R. Alfano, "Second-harmonic tomography of tissues, " Opt. Lett. 22(17), 1323-1325 (1997).
3. W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, "Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation, " Proc. Natl. Acad. Sci. U.S.A. 100(12), 7075-7080 (2003).
4. M. J. Levene, D. A. Dombeck, K. A. Kasischke, R. P. Molloy, and W. W. Webb, "In vivo multiphoton microscopy of deep brain tissue, " J. Neurophysiol. 91(4), 1908-1912 (2004).
5. J. C. Jung, A. D. Mehta, E. Aksay, R. Stepnoski, and M. J. Schnitzer, "In vivo mammalian brain imaging using one-and two-photon fluorescence microendoscopy, " J. Neurophysiol. 92(5), 3121-3133 (2004).
6. B. A. Flusberg, J. C. Jung, E. D. Cocker, E. P. Anderson, and M. J. Schnitzer, "In vivo brain imaging using a portable 3.9 gram two-photon fluorescence microendoscope, " Opt. Lett. 30(17), 2272-2274 (2005).
7. M. T. Myaing, D. J. MacDonald, and X. D. Li, "Fiber-optic scanning two-photon fluorescence endoscope, " Opt. Lett. 31(8), 1076-1078 (2006).
8. L. Fu, A. Jain, H. K. Xie, C. Cranfield, and M. Gu, "Nonlinear optical endoscopy based on a double-clad photonic crystal fiber and a MEMS mirror, " Opt. Express 14(3), 1027-1032 (2006).
9. Y. C. Wu, J. F. Xi, M. J. Cobb, and X. D. Li, "Scanning fiber-optic nonlinear endomicroscopy with miniature aspherical compound lens and multimode fiber collector, " Opt. Lett. 34(7), 953-955 (2009).
10. Y. C. Wu, Y. X. Leng, J. F. Xi, and X. D. Li, "Scanning all-fiber-optic endomicroscopy system for 3D nonlinear optical imaging of biological tissues, " Opt. Express 17(10), 7907-7915 (2009).
11. H. Cang, T. Sun, Z. Y. Li, J. Y. Chen, B. J. Wiley, Y. N. Xia, and X. D. Li, "Gold nanocages as contrast agents for spectroscopic optical coherence tomography, " Opt. Lett. 30(22), 3048-3050 (2005).
12. X. M. Liu, M. J. Cobb, Y. C. Chen, M. B. Kimmey, and X. D. Li, "Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography, " Opt. Lett. 29(15), 1763-1765 (2004).
13. A. K. Dunn, C. Smithpeter, A. J. Welch, and R. Richards-Kortum, "Sources of contrast in confocal reflectance imaging, " Appl. Opt. 35(19), 3441-3446 (1996).
14. J. M. Schmitt, and K. Ben-Letaief, "Efficient Monte Carlo simulation of confocal microscopy in biological tissue, " J. Opt. Soc. Am. A 13(5), 952-961 (1996).
15. A. K. Dunn, V. P. Wallace, M. Coleno, M. W. Berns, and B. J. Tromberg, "Influence of optical properties on two-photon fluorescence imaging in turbid samples, " Appl. Opt. 39(7), 1194-1201 (2000).
16. E. Beaurepaire, M. Oheim, and J. Mertz, "Ultra-deep two-photon fluorescence excitation in turbid media, " Opt. Commun. 188(1-4), 25-29 (2001).
17. J. N. Qu, C. Macaulay, S. Lam, and B. Palcic, "Optical properties of normal and carcinomatous bronchial tissue, " Appl. Opt. 33(31), 7397-7405 (1994).
18. R. Drezek, K. Sokolov, U. Utzinger, I. Boiko, A. Malpica, M. Follen, and R. Richards-Kortum, "Understanding the contributions of NADH and collagen to cervical tissue fluorescence spectra: modeling, measurements, and implications, " J. Biomed. Opt. 6(4), 385-396 (2001).
19. T. Collier, D. Arifler, A. Malpica, M. Follen, and R. Richards-Kortum, "Determination of epithelial tissue scattering coefficient using confocal microscopy, " IEEE J. Quantum Electron. 9(2), 307-313 (2003).
20. S. K. Chang, D. Arifler, R. Drezek, M. Follen, and R. Richards-Kortum, "Analytical model to describe fluorescence spectra of normal and preneoplastic epithelial tissue: comparison with Monte Carlo simulations and clinical measurements, " J. Biomed. Opt. 9(3), 511-522 (2004).
21. K. König, A. Ehlers, I. Riemann, S. Schenkl, R. Bückle, and M. Kaatz, "Clinical two-photon microendoscopy, " Microsc. Res. Tech. 70(5), 398-402 (2007).