Anti diabetic effect of achyranthes rubrofusca leaf extracts on alloxan induced diabetic rats

Pakistan Journal of Pharmaceutical Sciences

Volumn 24, Issue 2, 2011, Pages 193-199

  Geetha, Govindarajulu ^a   Gopinathapillai, Prasanth Kalavalarasariel ^a   Sankar, Veindramuthu ^a  

^a PSG COLLEGE OF PHARMACY   (India)

Author keywords

Achyranthes rubrofusca L.; Alloxan; Diabetic; Hypolipidemic

Indexed keywords

ACHYRANTHES RUBROFUSCA EXTRACT; ALCOHOL; ALLOXAN; ANTIDIABETIC AGENT; GLIBENCLAMIDE; GLUCOSE; GLUTATHIONE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ACHYRANTHES; ACHYRANTHES RUBROFUSCA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ACTIVITY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGIC SKIN REACTION; MEDICINAL PLANT; NONHUMAN; PANCREAS FUNCTION; PLANT LEAF; PROTEIN EXPRESSION;

ACHYRANTHES; ALLOXAN; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; LIPIDS; MALE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR;

EID: 79953872164     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Aminuddin RDG and Khan SA (1992). Ethnomedicinal uses of Achyranthes aspera Linn. In: Orissa (India). International Journal of Pharmacognosy, 30(2): 113-115.
2. Beutler E, Duron O and Kefly BM (1963). Improved method for the determination of blood glutathione. J. Lab. Clin. Med., 61: 882-888.
3. Bopanna KN, Kannan J, Gadgil S, Balaraman ER and Rathore SP (1997). Antidiabetic and antihyperglycaemic effects of neem seeds kernel powder on alloxan diabetic rabbits. Indian Journal of Pharmacology, 29: 62-67.
4. Pitchai D, Saravana AB and Modilal R (2009). Antihyperglycemic effects of phyllanthus extracts in alloxan-induced diabetic rats. Int. J. Ph. Sci., 1(2): 261-264.
5. Dunn JS, Sheehan HL and McLetchie NGB (1943). Necrosis of islets of Langerhans produced experimentally, Lancet, 244: 484-487
6. Foster CS and Dunn O (1973). Stable reagent for determination of Serum triglycerides by Colorimetric Hantzsh condensation method. Clin. Chem., 19: 338-340.
7. Galigher AE and Kozloff EN (1971). Essential Practical Microtechnique. Lea and Feigner, Philadelphia 2nd edition, pp.77-82.
8. Geetha G, Chandrasekhara AK, Brinda P and Shymala G (2006). Preliminary Phytochemical and Pharmacognostical studies of Achyranthes rubrofusca Linn. Hamdard Medicus. XLIX(4): 115-120.
9. Grankvist K and Marklud S (1981). Taljedal., superoxide dismutase is aprophylactic against alloxan diabetes. IB Natural. Indian J. Physiol. Pharmacol., 41: 353-360.
10. Hevener A, Reichart D, Jenez A and Olefsky J (2002). Female rats do not exhibit 294(5837): 158-160.
11. Hakim ZS, Patel BK and Goyal RK (1997). Effect of chronic ramipril treatment in streptozotocin- induced diabetic rats. free fatty acid-induced insulin resistance. Diabetes, 51: 1907-1912.
12. Howard BV, Savage PJ, Bennion LJ and Bennett PH (1978). Lipoprotein composition in diabetes mellitus. Atherosclerosis; 30: 153-162. (Pubitemid 8353285)
13. Kamalakkannan N and Prince PS. (2006) Antihyperglycaemic and antioxidant effect of rutin, polyphenolic flavonoid, in streptozotocininduceddiabetic wistar rats. Basic Clin. Pharmacol. Toxicol., 98: 97-103.
14. Lenzen S and Panten U (1988). History and mechanism of action. Diabetologia, 31: 337-342.
15. Lubec B, Hayn M, Denk W and Bauer G (1996). Brain lipideroxidation and hydroxylradical attack following the intravenous infusion of hydrogen peroxide in an infant. Free Rad. Bio. Med., 21: 219-223. (Pubitemid 26249608)
16. Milagro FI and Martínez JA (2000). Effect of the oral administration of a beta 3-adrenergic agonist on lipid metabolism in alloxan-diabetic rats. J. Pharm. Pharmacol., 52: 851-856. (Pubitemid 30461919)
17. Misra HP and Frisovich I (1979). The role of suopetr oxide anion in the antioxidant of epinephrine and simple assay for SOD. J. Biolchem., 2457: 3170-3175.
18. Nagarajan NS, Murugesh N, Thirupathy Kumaresan P, Radha N and Murali A (2005). Antidiabetic and antihyperlipemic effects of Clemeo feline. Fitoterapia, 76: 310-315. (Pubitemid 40745205)
19. Nikkilä EA and Kekki M (1973). Plasma triglyceride transport kinetics in diabetes mellitus. Metabolism, 22: 1-22.
20. Odetola AA, Akinloye O, Egunjobi C, Adekunle WA and Ayoola AO (2006). Possible antidiabetic and antihyperlipidaemic effect of fermented Parkia Biglobosa (JACQ) extract in alloxan-induced diabetic rats. Clin. Exp. Pharmacol. Physiol., 33: 808-812. (Pubitemid 44215134)
21. Ohkawa H, Ohishi N and Yagi K (1979). Assay for Lipid Peroxides in Animal Tissues by Thio-Barbituric Acid Reaction. Anal. Biochem., 95: 357-358.
22. Oliver B (1980). Oral hypoglycemic plants in West Africa. J. Ethnopharmacolgy, 2: 119-127.
23. Parekh AC and Jung DH (1970). Determination of Cholesterol with Ferric acetate. Uranium acetate and sulphuric acid -Ferrous sulphate reagent. Anal. Chem., 442: 1523-1529.
24. Pari L and Saravanan R (2004). Antidiabetic effect of diasulin, an herbal drug, on blood glucose, plasma insulin and hepatic enzymes of glucose metabolism in hyperglycaemic rats. Diabetes Obes. Metab., 6: 286-292. (Pubitemid 38807803)
25. Rajasekaran S, Ravi K, Sivagnanam K and Subramanian S (2006). Beneficial effects of aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clin. ExpPharmacol. Physiol., 33: 232-237.
26. Rajkumar L, Srinivasan N, Balasubramanian K and Govindarajulu P (1991). Increased degradation of dermal collagen in diabetic rats. Indian J. Exp. Biol., 29: 1081-1083.
27. Sasaki T, Mutsui and Sonac, (1972). Effect of acetic acid concentration on the colour reaction in the O-toludine - boric acid for blood glucose estimation. Rinshodagaker, 1: 346-353.
28. Sinha AK (1972). Calorimetric assay of catalase. Anal. Biochem., 4: 389-394.
29. Tiedge M, Lortz S, Drinkgern J and Lenzen S (1997). Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells. Diabetes, 46(11): 1733-1742. (Pubitemid 27456404)
30. Trivedi NA, Mazumdar B, Bhatti JD and Hemavathi KG (2004). Effect of shilagit on blood glucose and lipid profile in alloxan induced diabetic rats. Indian Journal of Pharmacology, 36: 373-376. (Pubitemid 40372254)