Tumor-in-tumor of the thyroid with basaloid differentiation: A lesion with a solid cell nest neoplastic component?

International Journal of Surgical Pathology

Volumn 19, Issue 2, 2011, Pages 276-280

  Eloy, Catarina ^a,b   Vinagre, João ^b   Cameselle Teijeiro, José ^c   Paiva, Maria Emília ^a   Soares, Paula ^b   Sobrinho Simões, Manuel ^a,b  

^a HOSPITAL DE SÃO JOÃO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

basaloid carcinoma; follicular variant of papillary thyroid carcinoma; N RAS; solid cell nests; thyroid; tumor in tumor

Indexed keywords

B RAF KINASE; CALCITONIN; CARCINOEMBRYONIC ANTIGEN; CD5 ANTIGEN; CYTOKERATIN; CYTOKERATIN 20; GALECTIN 3; PROTEIN P63; RADIOACTIVE IODINE; RAS PROTEIN; THYROGLOBULIN; THYROID TRANSCRIPTION FACTOR 1; KERATIN;

ADENOMA; AGED; ARTICLE; ASPIRATION BIOPSY; BASAL CELL; CASE REPORT; CELL DEATH; CELL DIFFERENTIATION; CELL INVASION; CYTOLOGY; FOLLICULAR VARIANT OF PAPILLARY THYROID CARCINOMA; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROFOLLICULAR ADENOMA; MITOSIS RATE; PATHOLOGY; PHENOTYPE; PRIORITY JOURNAL; THYROID TUMOR; THYROIDECTOMY; ULTRASOUND; ADENOCARCINOMA;

ADENOCARCINOMA, FOLLICULAR; GALECTIN 3; HUMANS; KERATINS; THYROGLOBULIN;

EID: 79953867373     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896910393506     Document Type: Article

References (20)

1. Yu J., Nikiforova MN, Hodak SP, et al. Tumor-to-tumor metastases to follicular variant of papillary thyroid carcinoma: histologic, immunohistochemical, and molecular studies of two unusual cases. Endocr Pathol. 2009 ; 20: 235-242.
2. Fusco A., Chiappetta G., Hui P., et al. Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphologic evidence of papillary carcinoma: a search for the early precursors of papillary cancer. Am J Surg Pathol. 2002 ; 16: 2157-2167. (Pubitemid 34663407)
3. Getzowa S. Über die Glandula parathyroidea, intrthyreoidale Zellhaufen derselben und Reste des postbranchialen köpers. Virchows Arch A Pathol Anat Histopathol. 1907 ; 188: 181-234.
4. Harach HR Solid cell nests of the thyroid. J Pathol. 1988 ; 155: 191-200.
5. Cameselle-Teijeiro J., Varela-Durán J., Sambade C., Vilanueva JP, Varela-Núñez R., Sobrinho-Simões M. Solid cell nests of the thyroid: light microscopy and immunohistochemical profile. Hum Pathol. 1994 ; 25: 684-693. (Pubitemid 24230747)
6. Reis-Filho JS, Preto A., Soares P., Ricardo C., Cameselle-Teijeiro J., Sobrinho-Simões M. p63 expression in solid cell nests of the thyroid: further evidence for a stem cell origin. Mod Pathol. 2003 ; 16: 43-48. (Pubitemid 36152685)
7. Cameselle-Teijeiro J., Abdulkader I., Pérez-Becerra R., et al. BRAF mutation in solid cell nest hyperplasia associated with papillary thyroid carcinoma. A precursor lesion?. Hum Pathol. 2009 ; 40: 1029-1035.
8. Fellegara G., Dorji T., Bajineta MR, Rosai J. " Giant" solid cell rest of the thyroid: a hyperplastic change ? Int J Surg Pathol. 2009 ; 17: 268-269.
9. Cameselle-Teijeiro J., Menasce LP, Yap BK, et al. Cribriformmorular variant of papillary thyroid carcinoma: molecular characterization of a case with neuroendocrine differentiation and aggressive behavior. Am J Clin Pathol. 2009 ; 131: 134-142.
10. DeLellis RA, Lloyd RV, Heitz PU, Eng C., eds. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Endocrine Organs. Lyon, France: IARC Press ; 2004.
11. Cameselle-Teijeiro J., Pardal F., Eloy C., et al. Follicular thyroid carcinoma with an unusual glomeruloid pattern of growth. Hum Pathol. 2008 ; 39: 1540-1547.
12. Cameselle-Teijeiro J., Varela-Durán J. Intrathyroid salivary gland-type tissue in multinodular goiter. Virchows Arch. 1994 ; 425: 331-334. (Pubitemid 24368916)
13. Wheeler MH, Williams ED, Wade JS The hyperfunctioning intrathyroidal parathyroid gland: a potential pitfall in parathyroid surgery. World J Surg. 1987 ; 11: 110-114. (Pubitemid 17003001)
14. Mizukami Y., Nanomura A., Michigishi T., Noguchi N., Nakamura S. Ectopic thymic tissue in the thyroid gland. Endocr Pathol. 1993 ; 4: 162-164.
15. Lange MJ Pleomorphic adenoma of the thyroid containing salivary gland cells with pseudocartilage and myoepithelial cells. Int Surg. 1974 ; 59: 178-179.
16. Chemlal K., Cacoub P., Maksud P., Chapuis Y., Godeau P. Parathyroid adenoma encapsulated in a thyroid adenoma: an anatomical curiosity [in French]. Rev Med Interne. 1994 ; 15: 340-343. (Pubitemid 24185841)
17. Reimann JD, Dorfman DM, Nosé V. Carcinoma showing thymus-like differentiation of the thyroid (CASTLE): a comparative study: evidence of thymic differentiation and solid cell nest origin. Am J Surg Pathol. 2006 ; 30: 994-1001. (Pubitemid 44264949)
18. Chan JK, Rosai J. Tumors of the neck showing thymic or related branchial pouch differentiation: a unifying concept. Hum Pathol. 1991 ; 22: 349-367.
19. Faggiano A., Talbot M., Baudin E., Bidart JM, Schlumberger M., Caillou B. Differential expression of galectin 3 in solid cell nests and C cells of human thyroid. J Clin Pathol. 2003 ; 56: 142-143. (Pubitemid 36177259)
20. Harmond BG, Kelley L. Immunohistochemistry of ultimo-branchial thyroid carcinomas in seven slaughtered cows and one bull. J Vet Diagn Invest. 2001 ; 13: 101-105. (Pubitemid 33654170)