Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase

Journal of Organic Chemistry

Volumn 76, Issue 6, 2011, Pages 1838-1843

  Heaps, Nicole A ^a,b   Poulter, C Dale ^a  

^a UNIVERSITY OF UTAH   (United States)

^b Sapphire Energy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLYLIC SUBSTRATES; CARBON-OXYGEN BONDS; CO-SUBSTRATE; DIPHOSPHATES; DOUBLE BONDS; ELECTROPHILIC ALKYLATIONS; FARNESYL DIPHOSPHATE; FARNESYL DIPHOSPHATE SYNTHASE; HETEROLYTIC CLEAVAGE; ISOPENTENYL DIPHOSPHATE; METHYL GROUP; RATE-LIMITING STEPS;

ALKYLATION; CHLORINE; COMPENSATION (PERSONNEL); FUNCTIONAL GROUPS; OXYGEN;

SUBSTRATES;

ALLYL COMPOUND; CARBON; CHLORINE; DIMETHYLALLYL DIPHOSPHATE; FARNESYL DIPHOSPHATE; GERANYL DIPHOSPHATE; GERANYLTRANSFERASE; ISOPENTENYL DIPHOSPHATE; METHYL GROUP; OXYGEN; PYROPHOSPHORIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL BOND; CHLORINATION; ELECTROPHILICITY; ENZYME SUBSTRATE; FOWL; SYNTHESIS;

ANIMALS; GERANYLTRANSTRANSFERASE; HALOGENATION; HEMITERPENES; KINETICS; MODELS, MOLECULAR; ORGANOPHOSPHORUS COMPOUNDS; PROTEIN CONFORMATION;

EID: 79953842299     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo1024305     Document Type: Article

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