Synthesis and biological evaluation of some Schiff bases of [4-(amino)-5-phenyl-4H-1,2,4-triazole-3-thiol]

Pakistan Journal of Pharmaceutical Sciences

Volumn 24, Issue 2, 2011, Pages 109-112

  Jubie, Selvaraj ^a   Sikdar, Pranabesh ^a   Antony, Shanish ^a   Kalirajan, Rajagopal ^a   Gowramma, Byran ^a   Gomathy, Subramanian ^a   Elango, Kannan ^a  

^a JSS COLLEGE OF PHARMACY   (India)

Author keywords

Antianxiety; Antidepressant; Schiff bases; Triazole

Indexed keywords

[4 (AMINO) 5 PHENYL 4H 1,2,4 TRIAZOLE 3 THIOL]; ALDEHYDE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BENZALDEHYDE; FURFURAL; HYDRAZINE; SCHIFF BASE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; FORCED SWIMMING TEST; INFRARED SPECTROSCOPY; MALE; MASS SPECTROMETRY; MELTING POINT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSICAL PARAMETERS; SOLUBILITY; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; MALE; MICE; MOLECULAR STRUCTURE; SCHIFF BASES; TRIAZOLES;

EID: 79953840358     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Banachiwicz BM, Banachiwicz J, Chodkowska A, Wojtowicz EJ and Mazur L (2004). Synthesis and biological activity of new derivatives of 3-(3,4-diaryl-1,2,4-triazole-5-yl) propenoic acid. Eur. J. Med. Chem., 39: 873-877. (Pubitemid 39298444)
2. Dimova V, Ragenovic KC, Kakurinov V, Molnar DG and Buzarovaska A (2001). Synthesis, Antibacterial and antifungal activity of 4-substitued-5-aryl-1,2,4- triazole. Molecules, 6: 815-824. (Pubitemid 38990277)
3. Holla BS, Veerendra B, Shivananda MK and Poojary B (2003). Synthesis and characterization and anticancer activity studies on some Mannich bases derived from 1,2,4 - triazoles. Eur. J. Med. Chem., 38: 759-767. (Pubitemid 36976785)
4. Mathew V, Keshavayya J, Vaidya VP and Giles D (2007). Studies on synthesis and Pharmacological activities of 3,6-disubstitued-1,2,4-triazole-[3, 4-b]-1,3,4- thiadiazoles and their dihydro analogues. Eur. J. Med. Chem., 42: 823-840. (Pubitemid 46830679)
5. Sharma R, Yadav N and Chaturvedi SC (2008). Synthesis and biological evaluation of central nervous system agents. Ind. Drugs, 45(11): 859-868.
6. Wu J, Liu X, Cheng X, Cao Y, Wang D and Li Z (2007). Synthesis of novel derivatives of 4-amino-3-(2-furyl)-5- mercapto-1,2,4-triazole as potential HIV-1NNRTIs. Molecules, 12: 2003-2016.
7. Zangrossi H, Oliveira AM, Soares VP, Jorge SD and Pobbe RLH (2004). Effect of sibutramine on anxietyrelated behaviors in rats. Pharmacol. Res., 50: 517-522. (Pubitemid 39349054)