Hypoglycemic effect of ethanolic extract of Carum carvi L. seeds in normal and streptozotocin-induced diabetic rats

Journal of Medicinal Plants

Volumn 9, Issue 35, 2010, Pages 106-113

  Eidi, A ^a   Eidi, M ^b   Haeri Rohani, A ^a   Basati, F ^a  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Caraway; Carum carvi L.; Diabetes; Rat; Streptozotocin

Indexed keywords

ANTIDIABETIC AGENT; CARUM CARVI EXTRACT; GLUCOSE; INSULIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARAWAY; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; MALE; NONHUMAN; PLANT SEED; RAT; STREPTOZOCIN DIABETES;

CARUM CARVI; RATTUS;

EID: 79953840274     PISSN: 2717204X     EISSN: 27172058     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Leroith D, Smith DO. Monitoring glycemic control: the cornerstone of diabetes care. Clinical Therapeutics 2005; 27: 1489-99.
2. Bottini N, Vang T, Cucca F, Mustelin T. Role of PTPN22 in type 1 diabetes and other autoimmune diseases. Seminars in Immunol. 2006; 18: 207-13. (Pubitemid 43903283)
3. Warren RE. The stepwise approach to the management of type 2 diabetes. Diabetes Research and Clinical Practice 2004; 65: 53-8.
4. Dubey GP, Dixit SP, Alok S. Alloxan-induced diabetes in rabbits and effect of herbal formulation D-400. Indian J. Pharmacol. 1994; 26: 225-6.
5. Prince PS, Menon VP, Pari L. Hypoglycemic activity of Syzigium cuminii seeds: effect on lipid peroxidation in alloxan diabetes rats. J. Ethnopharmacol. 1998; 61: 1-7. (Pubitemid 28276718)
6. Ladeji O, Omekarah I, Solomon M. Hypoglycemic properties of aqueous bark extract of Ceiba pentandra in streptozotocin-induced diabetic rats. J. Ethnopharmacol. 2003; 84: 139-42. (Pubitemid 36324250)
7. Geetha BS, Biju CM, Augusti KT. Hypoglycemic effects of leucodelphinidin derivative isolated from Ficus bengalensis (Linn.). Indian J. Pharmacol. 1994; 38: 220-2. (Pubitemid 24279458)
8. Rao BK, Sudarshan PR, Rajasekhar MD, Nagaraju N, Rao CA. Antidiabetic activity of Terminalia pallida fruit in alloxan induced diabetic rats. J. Ethnopharmacol. 2003; 85: 169-72. (Pubitemid 36170070)
9. Grover JK, Yadav S, Vats V. Medicinal plants of India with antidiabetes potential. J Ethnopharmacol 2002; 81: 81-100. (Pubitemid 34518472)
10. Vats V, Grover JK, Rathi SS. Evaluation of antihyperglycemic effect of Trigonella foenum-graecum Linn., Occium sanctum Linn, and Pterocarpus marsupium Linn., in normal and alloxanised diabetic rats. J. Ethnopharamcol. 2002; 79: 95-100. (Pubitemid 34017246)
11. Holtmann G, Haag S, Adam B, Funk P, Wieland V, Heydenreich CJ. Effects of a fixed combination of peppermint oil and caraway oil on symptoms and quality of life in patients suffering from functional dyspepsia. Phytomedicine 2003; 10: 56-7. (Pubitemid 36597158)
12. Madisch A, Holtmann G, Mayr G, Vinson B, Hotz J. Treatment of functional dyspepsia with a herbal preparation: a double-blind, randomized, placebo-controlled, multicenter trial. Digestion 2004; 69: 45-52. (Pubitemid 38332924)
13. Thompson Coon J, Ernst E. Systematic review: herbal medicinal products for non-ulcer dyspepsia. Alimen Pharmacol Therap 2002; 16: 1689-99.
14. Reynolds JEF. The Extra Pharmacopoeia, 30th ed. Pharmaceutical Press, London, 1993, pp: 1349-50.
15. Bellakhdar J. La Pharmacopée Marocaine Traditionnelle, Médecine Arabe Ancienne et Savoirs Populaires. Edition Ibis Press, 1997, pp: 150.
16. Khayyal MT, El-Ghazaly MA, Kenawy SA, Seif-El-Nasr M, Mahran LG, Kafafi YA, Okpanyi SN. Antiulcerogenic effect of some gastrointestinally acting plant extracts and their combination. Arzneimittelforschung 2001; 51: 545-53. (Pubitemid 32664392)
17. Zheng G, Kenney PM, Lam LKT. Anethofuran, carvone, and limonene: potential cancer chemopreventive agents from dill weed oil and caraway oil. Planta Med. 1992; 58: 338-41.
18. Nakano Y, Matsunaga H, Saita T, Mori M, Katano M, Okabe H. Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii. Biol. Pharm. Bull 1998; 21: 257-61.
19. Eddouks M, Lemhadri A, Michel JB. Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats. J. Ethnopharmacol. 2004; 94: 143-8. (Pubitemid 38942846)
20. Iacobellis NS, Lo Cantore P, Capasso F,. Senatore F. Antibacterial activity of Cuminum cyminum L. and Carum carvi L. essential oils. J. Agric Food Chem. 2005; 53: 57-61. (Pubitemid 40066470)
21. Madway W, Prier IE, Wilkinson JS. A Text Book of Veterinary Clinical Pathology. The Williams and Wilkins Co., Baltimore, 1969, p: 256.
22. Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. 1969; 6: 24-8.
23. Ram JL, Fares MA, Standley PR, Sowers JR. Insulin inhibits vasopressin-elicited contraction of vascular smooth muscle cells. J. Vasc Med. Biol. 1993; 4: 250-5.
24. Burcelin R, Eddouks M, Maury J, Kande J, Assan R, Girard J. Excessive glucose production, ramer than insulin resistance, accounts for hyperglycaemia in recent-onset streptozotocin-diabetic rats. Diabetologia 1995; 38: 283-90.
25. Eisner M, Guldbakke B, Tiedge M, Nunday R, Lenzen S. Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin. Diabetologia 2000; 43: 1528-33. (Pubitemid 32734859)
26. Matsuda M, Kawasaka F, Mikami Y, Takeuchi Y, Saito M, Eto M, Kaku K. Rescue of beta-cell exhaustion by diazoxide after the development of diabetes mellitus in rats with steptozotocin-induced diabetes. European J. Pharmacol. 2002; 431: 141-8.
27. Matsumura T, Ishikawa T, Kitajima J. Water-soluble constituents of caraway: carvone derivatives and their glucosides. Chemical and Pharmceutical Bulletin 2002; 50: 66-72. (Pubitemid 44724581)
28. Gersbach PV, Reddy N. Non-invasive localization of thymol accumulation in Carum carvi copticum (Apiaceae) fruits by chemical shift selective magnetic resonance imaging. Annals of Botany (London) 2002; 90: 253-7. (Pubitemid 34842204)
29. Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R. Biosynthesis of the Monoterpenes limonene and carvone in the fruit of caraway. Plant Physiol. 1998; 117: 901-12.
30. Kunzermann J, Herrmann K. Isolation and identification of flavon(ol)-O-glycosides in caraway (Carum carvi L.) fennel (Foeniculum vulgare Mill.), anise (Pimpinelle anisum L.), and coriander (Coriandrum sativum L.), and flavon-C-glycosides in anise. L. Phenolics of spices. Zeitschrift fur Lebensmittel-Untersuchung und-Forschung 1977; 164: 194-200.
31. Havsteen BH. The biochemistry and medical significance of the flavonoids. Pharmacology and Therapeutics 2002; 96 (2-3): 67-202.
32. Eddouks M, Jouad H, Maghrani M, Lemhadri A, Burcelin R. Inhibition of endogenous glucose production accounts for hypoglycaemic effect of Spergularia purpurea in diabetic mice. Phytomedicine 2003; 10: 594-9. (Pubitemid 37092687)
33. Maghrani M, Lemhadri A, Jouad H, Michel JB, Eddouks M. Effect of the desert plant Retama raetam on glycaemia in normal and streptozotocin-induced diabetic rats. J. Ethnopharmacol. 2003; 87 (1): 21-5. (Pubitemid 36644969)