-
1
-
-
0036467376
-
Dynamics of the immunological synapse: Finding, establishing and solidifying a connection
-
DOI 10.1016/S0952-7915(01)00299-0
-
Krummel, M.F. & Davis, M.M. Dynamics of the immunological synapse: fnding, establishing and solidifying a connection. Curr. Opin. Immunol. 14, 66-74 (2002). (Pubitemid 34085108)
-
(2002)
Current Opinion in Immunology
, vol.14
, Issue.1
, pp. 66-74
-
-
Krummel, M.F.1
Davis, M.M.2
-
2
-
-
33751547539
-
How many drug targets are there?
-
DOI 10.1038/nrd2199, PII NRD2199
-
Overington, J.P., Al-Lazikani, B. & Hopkins, A.L. How many drug targets are there? Nat. Rev. Drug Discov. 5, 993-996 (2006). (Pubitemid 44835126)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.12
, pp. 993-996
-
-
Overington, J.P.1
Al-Lazikani, B.2
Hopkins, A.L.3
-
3
-
-
0037082324
-
Target validation of G-protein coupled receptors
-
DOI 10.1016/S1359-6446(01)02131-6, PII S1359644601021316
-
Wise, A., Gearing, K. & Rees, S. Target validation of G-protein coupled receptors. Drug Discov. Today 7, 235-246 (2002). (Pubitemid 34143072)
-
(2002)
Drug Discovery Today
, vol.7
, Issue.4
, pp. 235-246
-
-
Wise, A.1
Gearing, K.2
Rees, S.3
-
4
-
-
11444266196
-
Label-free molecular interaction determinations with nanoscale interferometry
-
DOI 10.1021/ja047820m
-
Markov, D.A., Swinney, K. & Bornhop, D.J. Label-free molecular interaction determinations with nanoscale interferometry. J. Am. Chem. Soc. 126, 16659-16664 (2004). (Pubitemid 40081968)
-
(2004)
Journal of the American Chemical Society
, vol.126
, Issue.50
, pp. 16659-16664
-
-
Markov, D.A.1
Swinney, K.2
Bornhop, D.J.3
-
5
-
-
33750012640
-
Highly sensitive biosensing based on interference from light scattering in capillary tubes
-
Sorensen, H.S., Larsen, N.B., Latham, J.C., Bornhop, D.J. & Andersen, P.E. Highly sensitive biosensing based on interference from light scattering in capillary tubes. Appl. Phys. Lett. 89, 151108 (2006).
-
(2006)
Appl. Phys. Lett.
, vol.89
, pp. 151108
-
-
Sorensen, H.S.1
Larsen, N.B.2
Latham, J.C.3
Bornhop, D.J.4
Andersen, P.E.5
-
6
-
-
34648815160
-
Free-solution, label-free molecular interactions studied by back-scattering interferometry
-
DOI 10.1126/science.1146559
-
Bornhop, D.J. et al. Free-solution, label-free molecular interactions studied by back-scattering interferometry. Science 317, 1732-1736 (2007). (Pubitemid 47461834)
-
(2007)
Science
, vol.317
, Issue.5845
, pp. 1732-1736
-
-
Bornhop, D.J.1
Latham, J.C.2
Kussrow, A.3
Markov, D.A.4
Jones, R.D.5
Sorensen, H.S.6
-
7
-
-
67249140316
-
Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scattering interferometry
-
Kussrow, A. et al. Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scattering interferometry. Anal. Chem. 81, 4889-4897 (2009).
-
(2009)
Anal. Chem.
, vol.81
, pp. 4889-4897
-
-
Kussrow, A.1
-
8
-
-
33845596453
-
Gangliosides as components of lipid membrane domains
-
DOI 10.1093/glycob/cwl052
-
Sonnino, S., Mauri, L., Chigorno, V. & Prinetti, A. Gangliosides as components of lipid membrane domains. Glycobiology 17, 1R-13R (2007). (Pubitemid 44932810)
-
(2007)
Glycobiology
, vol.17
, Issue.1
-
-
Sonnino, S.1
Mauri, L.2
Chigorno, V.3
Prinetti, A.4
-
9
-
-
0027489512
-
Gangliosides as receptors for bacterial enterotoxins
-
Fishman, P.H., Pacuszka, T. & Orlandi, P.A. Gangliosides as receptors for bacterial enterotoxins. Adv. Lipid Res. 25, 165-187 (1993).
-
(1993)
Adv. Lipid Res.
, vol.25
, pp. 165-187
-
-
Fishman, P.H.1
Pacuszka, T.2
Orlandi, P.A.3
-
10
-
-
0029885779
-
Cholera toxin binding affinity and specificity for gangliosides determined by surface plasmon resonance
-
DOI 10.1021/bi952314i
-
Kuziemko, G.M., Stroh, M. & Stevens, R.C. Cholera toxin binding affnity and specifcity for gangliosides determined by surface plasmon resonance. Biochemistry 35, 6375-6384 (1996). (Pubitemid 26164071)
-
(1996)
Biochemistry
, vol.35
, Issue.20
, pp. 6375-6384
-
-
Kuziemko, G.M.1
Stroh, M.2
Stevens, R.C.3
-
11
-
-
0037418476
-
Ganglioside microarrays for toxin detection
-
Fang, Y., Frutos, A. & Lahiri, J. Ganglioside microarrays for toxin detection. Langmuir 19, 1500-1505 (2003).
-
(2003)
Langmuir
, vol.19
, pp. 1500-1505
-
-
Fang, Y.1
Frutos, A.2
Lahiri, J.3
-
12
-
-
27144531262
-
Cholesterol modulated antibody binding in supported lipid membranes as determined by total internal reflectance microscopy on a microfabricated high-throughput glass chip
-
DOI 10.1021/la0502645
-
Cannon, B. et al. Cholesterol modulated antibody binding in supported lipid membranes as determined by total internal refectance microscopy on a microfabricated high-throughput glass chip. Langmuir 21, 9666-9674 (2005). (Pubitemid 41507022)
-
(2005)
Langmuir
, vol.21
, Issue.21
, pp. 9666-9674
-
-
Cannon, B.1
Weaver, N.2
Pu, Q.3
Thiagarajan, V.4
Liu, S.5
Huang, J.6
Vaughn, M.W.7
Cheng, K.H.8
-
14
-
-
27944442353
-
Immunology: Altered TCR signaling from geometrically repatterned immunological synapses
-
DOI 10.1126/science.1119238
-
Mossman, K.D., Campi, G., Groves, J.T. & Dustin, M.L. Altered TCR signaling from geometrically repatterned immunological synapses. Science 310, 1191-1193 (2005). (Pubitemid 41681746)
-
(2005)
Science
, vol.310
, Issue.5751
, pp. 1191-1193
-
-
Mossman, K.D.1
Campi, G.2
Groves, J.T.3
Dustin, M.L.4
-
15
-
-
0042572380
-
Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system
-
DOI 10.1016/S1367-5931(03)00079-6
-
Cravatt, B.F. & Lichtman, A.H. Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. Curr. Opin. Chem. Biol. 7, 469-475 (2003). (Pubitemid 36980837)
-
(2003)
Current Opinion in Chemical Biology
, vol.7
, Issue.4
, pp. 469-475
-
-
Cravatt, B.F.1
Lichtman, A.H.2
-
16
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane, W.A. et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949 (1992). (Pubitemid 23026736)
-
(1992)
Science
, vol.258
, Issue.5090
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
17
-
-
68049090031
-
Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by α-ketoheterocycle inhibitors revealed from co-crystal structures
-
Mileni, M. et al. Binding and inactivation mechanism of a humanized fatty acid amide hydrolase by α-ketoheterocycle inhibitors revealed from co-crystal structures. J. Am. Chem. Soc. 131, 10497-10506 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 10497-10506
-
-
Mileni, M.1
-
18
-
-
20144377098
-
Discovery of a potent, selective, and efficacious class of reversible α-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics
-
DOI 10.1021/jm049614v
-
Boger, D.L. et al. Discovery of a potent, selective, and effcacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics. J. Med. Chem. 48, 1849-1856 (2005). (Pubitemid 40396316)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.6
, pp. 1849-1856
-
-
Boger, D.L.1
Miyauchi, H.2
Du, W.3
Hardouin, C.4
Fecik, R.A.5
Cheng, H.6
Hwang, I.7
Hedrick, M.P.8
Leung, D.9
Acevedo, O.10
Guimaraes, C.R.W.11
Jorgensen, W.L.12
Cravatt, B.F.13
-
19
-
-
33847783305
-
Potent and selective α-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase
-
DOI 10.1021/jm0611509
-
Romero, F.A. et al. Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. J. Med. Chem. 50, 1058-1068 (2007). (Pubitemid 46394008)
-
(2007)
Journal of Medicinal Chemistry
, vol.50
, Issue.5
, pp. 1058-1068
-
-
Romero, F.A.1
Du, W.2
Hwang, I.3
Rayl, T.J.4
Kimball, F.S.5
Leung, D.6
Hoover, H.S.7
Apodaca, R.L.8
Breitenbucher, J.G.9
Cravatt, B.F.10
Boger, D.L.11
-
20
-
-
49449114646
-
Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase
-
Garfunkle, J. et al. Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase. J. Med. Chem. 51, 4392-4403 (2008).
-
(2008)
J. Med. Chem.
, vol.51
, pp. 4392-4403
-
-
Garfunkle, J.1
-
22
-
-
0031975540
-
Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: Ligand binding, biological activity, and HIV-1 infectivity
-
Hesselgesser, J. et al. Identifcation and characterization of the CXCR4 chemokine receptor in human T cell lines: ligand binding, biological activity, and HIV-1 infectivity. J. Immunol. 160, 877-883 (1998). (Pubitemid 28049330)
-
(1998)
Journal of Immunology
, vol.160
, Issue.2
, pp. 877-883
-
-
Hesselgesser, J.1
Liang, M.2
Hoxie, J.3
Greenberg, M.4
Brass, L.F.5
Orsini, M.J.6
Taub, D.7
Horuk, R.8
-
23
-
-
4644296105
-
B receptor
-
DOI 10.1016/j.bcp.2004.06.035, PII S0006295204005258, Six Decades of GABA
-
B receptor. Biochem. Pharmacol. 68, 1565-1572 (2004). (Pubitemid 39286461)
-
(2004)
Biochemical Pharmacology
, vol.68
, Issue.8
, pp. 1565-1572
-
-
Pin, J.-P.1
Kniazeff, J.2
Binet, V.3
Liu, J.4
Maurel, D.5
Galvez, T.6
Duthey, B.7
Havlickova, M.8
Blahos, J.9
Prezeau, L.10
Rondard, P.11
-
24
-
-
0034760504
-
b receptors by 2,6-Di-tert-butyl-4-(3- hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501
-
B receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol. Pharm. 60, 963-971 (2001). (Pubitemid 33027431)
-
(2001)
Molecular Pharmacology
, vol.60
, Issue.5
, pp. 963-971
-
-
Urwyler, S.1
Mosbacher, J.2
Lingenhoehl, K.3
Heid, J.4
Hofstetter, K.5
Froestl, W.6
Bettler, B.7
Kaupmann, K.8
-
27
-
-
0029098821
-
B agonists
-
B agonists. J. Med. Chem. 38, 3297-3312 (1995).
-
(1995)
J. Med. Chem.
, vol.38
, pp. 3297-3312
-
-
Froestl, W.1
-
28
-
-
0027322113
-
The action of new potent GABA(B) receptor antagonists in the hemisected spinal cord preparation of the rat
-
DOI 10.1016/0014-2999(93)90836-7
-
Brugger, F., Wicki, U., Olpe, H.R., Froestl, W. & Mickel, S. The action of new potent GABA-B receptor antagonists in the hemisected spinal cord preparation of the rat. Eur. J. Pharmacol. 235, 153-155 (1993). (Pubitemid 23124085)
-
(1993)
European Journal of Pharmacology
, vol.235
, Issue.1
, pp. 153-155
-
-
Brugger, F.1
Wicki, U.2
Olpe, H.-R.3
Froestl, W.4
Mickel, S.5
-
29
-
-
64749106155
-
Free-solution label-free detection of α-crystallin chaperone interactions by back-scattering interferometry
-
Latham, J.C., Stein, R.A., Bornhop, D.J. & Mchaourab, H.S. Free-solution label-free detection of α-crystallin chaperone interactions by back-scattering interferometry. Anal. Chem. 81, 1865-1871 (2009).
-
(2009)
Anal. Chem.
, vol.81
, pp. 1865-1871
-
-
Latham, J.C.1
Stein, R.A.2
Bornhop, D.J.3
McHaourab, H.S.4
-
30
-
-
33748474838
-
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
-
DOI 10.1084/jem.20052144
-
Burns, J.M. et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J. Exp. Med. 203, 2201-2213 (2006). (Pubitemid 44352240)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.9
, pp. 2201-2213
-
-
Burns, J.M.1
Summers, B.C.2
Wang, Y.3
Melikian, A.4
Berahovich, R.5
Miao, Z.6
Penfold, M.E.T.7
Sunshine, M.J.8
Littman, D.R.9
Kuo, C.J.10
Wei, K.11
McMaster, B.E.12
Wright, K.13
Howard, M.C.14
Schall, T.J.15
-
31
-
-
0030894681
-
Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors
-
DOI 10.1038/386239a0
-
Kaupmann, K. et al. Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors. Nature 386, 239-246 (1997). (Pubitemid 27142503)
-
(1997)
Nature
, vol.386
, Issue.6622
, pp. 239-246
-
-
Kaupmann, K.1
Huggel, K.2
Heid, J.3
Flor, P.J.4
Bischoff, S.5
Mickel, S.J.6
McMaster, G.7
Angst, C.8
Bittiger, H.9
Froestl, W.10
Bettler, B.11
-
32
-
-
77953876440
-
The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease
-
Kussrow, A.K. et al. The potential of backscattering interferometry as an in vitro clinical diagnostic tool for the serological diagnosis of infectious disease. Analyst (Lond.) 135, 1535-1537 (2010).
-
(2010)
Analyst (Lond.)
, vol.135
, pp. 1535-1537
-
-
Kussrow, A.K.1
-
33
-
-
79551529077
-
Universal sensing by transduction of antibody binding using backscattering interferometry
-
Kussrow, A., Baksh, M.M., Bornhop, D.J. & Finn, M.G. Universal sensing by transduction of antibody binding using backscattering interferometry. ChemBioChem 12, 367-370 (2011).
-
(2011)
ChemBioChem
, vol.12
, pp. 367-370
-
-
Kussrow, A.1
Baksh, M.M.2
Bornhop, D.J.3
Finn, M.G.4
|