Viral interference with neuronal integrity: What can we learn from the Borna disease virus?

Cell and Tissue Research

Volumn 344, Issue 1, 2011, Pages 13-16

  Schwemmle, Martin ^a   Heimrich, Bernd ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Entorhinal projection; Hippocampus; Neurodegeneration; Rat; Synaptic reorganization

Indexed keywords

BORNA DISEASE VIRUS N LIKE PROTEIN; MARCKS PROTEIN; PROTEIN KINASE C; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; BORNA DISEASE VIRUS; BRAIN REGION; CELL DEATH; CELL FUNCTION; CELL LOSS; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM INFECTION; DENDRITE; ENTORHINAL CORTEX; GRANULE CELL; HIPPOCAMPAL MOSSY FIBER; HUMAN; NERVE CELL NETWORK; NERVE PROJECTION; NEUROPATHOLOGY; NONHUMAN; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA VIRUS INFECTION; SIGNAL TRANSDUCTION; VIRUS GENE; VIRUS INTERFERENCE; VIRUS REPLICATION; VIRUS TRANSMISSION;

ANIMALS; BORNA DISEASE; BORNA DISEASE VIRUS; BRAIN; CELLS, CULTURED; HOST-PATHOGEN INTERACTIONS; NEURONS; RATS; RATS, INBRED LEW;

BORNA DISEASE VIRUS; RATTUS;

EID: 79953816013     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00441-011-1141-6     Document Type: Article

References (18)

1. Belyi VA, Levine AJ, Skalka AM (2010) Unexpected inheritance: multiple integrations of ancient Borna virus and Ebola virus/Marburg virus sequences in vertebrate genomes. PLoS Pathog 6:e1001030
2. Dittrich W, Bode L, Ludwig H, Kao M, Schneider K (1989) Learning deficiencies in Borna disease virus-infected but clinically healthy rats. Biol Psychiatry 26:818-828 (Pubitemid 20016481)
3. Durrwald R, Kolodziejek J, Herzog S, Nowotny N (2007) Meta-analysis of putative human Borna virus sequences fails to provide evidence implicating Borna disease virus in mental illness. Rev Med Virol 17:181-203 (Pubitemid 46827222)
4. Gonzalez-Dunia D, Volmer R, Mayer D, Schwemmle M (2005) Borna disease virus interference with neuronal plasticity. Virus Res 111:224-234 (Pubitemid 40909738)
5. Heimrich B, Hesse DA, Wu YJ, Schmid S, Schwemmle M (2009) Borna disease virus infection alters synaptic input of neurons in rat dentate gyrus. Cell Tissue Res 338:179-190
6. Hilbe M, Herrsche R, Kolodziejek J, Nowotny N, Zlinszky K, Ehrensperger F (2006) Shrews as reservoir hosts of Borna disease virus. Emerg Infect Dis 12:675-677
7. Horie M, Honda T, Suzuki Y, Kobayashi Y, Daito T, Oshida T, Ikuta K, Jern P, Gojobori T, Coffin JM, Tomonaga K (2010) Endogenous non-retroviral RNA virus elements in mammalian genomes. Nature 463:84-87
8. Kamitani W, Shoya Y, Kobayashi T, Watanabe M, Lee BJ, Zhang G, Tomonaga K, Ikuta K (2001) Borna disease virus phosphoprotein binds a neurite outgrowth factor, amphoterin/HMG-1. J Virol 75:8742-8751 (Pubitemid 32768978)
9. Kamitani W, Ono E, Yoshino S, Kobayashi T, Taharaguchi S, Lee BJ, Yamashita M, Okamoto M, Taniyama H, Tomonaga K, Ikuta K (2003) Glial expression of Borna disease virus phosphoprotein induces behavioral and neurological abnormalities in transgenic mice. Proc Natl Acad Sci USA 100:8969-8974 (Pubitemid 36899207)
10. Mayer D, Fischer H, Schneider U, Heimrich B, Schwemmle M (2005) Borna disease virus replication in organotypic hippocampal slice cultures from rats results in selective damage of dentate granule cells. J Virol 79:11716-11723
11. Poenisch M, Burger N, Staeheli P, Bauer G, Schneider U (2009) Protein X of Borna disease virus inhibits apoptosis and promotes viral persistence in the central nervous systems of newborn-infected rats. J Virol 83:4297-4307
12. Prat CM, Schmid S, Farrugia F, Cenac N, Le Masson G, Schwemmle M, Gonzalez-Dunia D (2009) Mutation of the protein kinase C site in Borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity. PLoS Pathog 5:e1000425
13. Schneider U, Schwemmle M, Staeheli P (2005) Genome trimming: a unique strategy for replication control employed by Borna disease virus. Proc Natl Acad Sci USA 102:3441-3446 (Pubitemid 40328064)
14. Staeheli P, Sauder C, Hausmann J, Ehrensperger F, Schwemmle M (2000) Epidemiology of Borna disease virus. J Gen Virol 81:2123-2135
15. Tomonaga K (2010) Living fossil or evolving virus? EMBO Rep 11:327
16. Volmer R, Monnet C, Gonzalez-Dunia D (2006) Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling. PLoS Pathog 2:e19
17. Volmer R, Prat CM, Le Masson G, Garenne A, Gonzalez-Dunia D (2007) Borna disease virus infection impairs synaptic plasticity. J Virol 81:8833-8837 (Pubitemid 47242857)
18. Williams BL, Hornig M, Yaddanapudi K, Lipkin WI (2008) Hippocampal poly(ADP-ribose) polymerase 1 and caspase 3 activation in neonatal Borna virus infection. J Virol 82:1748-1758 (Pubitemid 351206925)