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Volumn 50, Issue 5, 2011, Pages 383-389

Overcoming resistance to fulvestrant (ICI182,780) by Downregulating the c-ABL Proto-Oncogene in breast cancer

Author keywords

Breast cancer; C ABL; Estrogen receptor; Fulvestrant; ICI182,780

Indexed keywords

ABELSON KINASE; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; IMATINIB;

EID: 79953804485     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20721     Document Type: Article
Times cited : (17)

References (34)
  • 1
    • 19644387170 scopus 로고    scopus 로고
    • Role of c-Abl in the DNA damage stress response
    • Shaul Y, Ben-Yehoyada M. Role of c-Abl in the DNA damage stress response. Cell Res 2005; 15: 33-35.
    • (2005) Cell Res , vol.15 , pp. 33-35
    • Shaul, Y.1    Ben-Yehoyada, M.2
  • 2
    • 0036391801 scopus 로고    scopus 로고
    • The Abl family kinases: Mechanisms of regulation and signaling
    • Pendergast AM. The Abl family kinases: Mechanisms of regulation and signaling. Adv Cancer Res 2002; 85: 51-100.
    • (2002) Adv Cancer Res , vol.85 , pp. 51-100
    • Pendergast, A.M.1
  • 3
    • 0345738562 scopus 로고    scopus 로고
    • Activation and signaling of the Abl tyrosine kinase: Bidirectional link with phosphoinositide signaling
    • Plattner R, Pendergast AM. Activation and signaling of the Abl tyrosine kinase: Bidirectional link with phosphoinositide signaling. Cell Cycle 2003; 2: 273-274.
    • (2003) Cell Cycle , vol.2 , pp. 273-274
    • Plattner, R.1    Pendergast, A.M.2
  • 4
    • 0032443366 scopus 로고    scopus 로고
    • Determination of cell fate by c-Abl activation in the response to DNA damage
    • Kharbanda S, Yuan ZM, Weichselbaum R, Kufe D. Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene 1998; 17: 3309-3318.
    • (1998) Oncogene , vol.17 , pp. 3309-3318
    • Kharbanda, S.1    Yuan, Z.M.2    Weichselbaum, R.3    Kufe, D.4
  • 5
    • 0034693878 scopus 로고    scopus 로고
    • Regulation of cell death by the Abl tyrosine kinase
    • Wang JY. Regulation of cell death by the Abl tyrosine kinase. Oncogene 2000; 19: 5643-5650.
    • (2000) Oncogene , vol.19 , pp. 5643-5650
    • Wang, J.Y.1
  • 6
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukemia-Advances in biology and new approaches to treatment
    • Goldman JM, Melo JV. Chronic myeloid leukemia-Advances in biology and new approaches to treatment. N Engl J Med 2003; 349: 1451-1464.
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 7
    • 35548969446 scopus 로고    scopus 로고
    • Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: Inhibition of c-Abl by the tumor suppressor gene product Fus1
    • Lin J, Sun T, Ji L, et al. Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: Inhibition of c-Abl by the tumor suppressor gene product Fus1. Oncogene 2007; 26: 6989-6996.
    • (2007) Oncogene , vol.26 , pp. 6989-6996
    • Lin, J.1    Sun, T.2    Ji, L.3
  • 8
    • 33745251071 scopus 로고    scopus 로고
    • Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells
    • Srinivasan D, Plattner R. Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells. Cancer Res 2006; 66: 5648-5655.
    • (2006) Cancer Res , vol.66 , pp. 5648-5655
    • Srinivasan, D.1    Plattner, R.2
  • 9
    • 39149121810 scopus 로고    scopus 로고
    • Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival
    • Srinivasan D, Sims JT, Plattner R. Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival. Oncogene 2008; 27: 1095-1105.
    • (2008) Oncogene , vol.27 , pp. 1095-1105
    • Srinivasan, D.1    Sims, J.T.2    Plattner, R.3
  • 10
    • 56149111255 scopus 로고    scopus 로고
    • Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells
    • Sirvent A, Benistant C, Roche S. Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells. Biol Cell 2008; 100: 617-631.
    • (2008) Biol Cell , vol.100 , pp. 617-631
    • Sirvent, A.1    Benistant, C.2    Roche, S.3
  • 11
    • 0023701360 scopus 로고
    • Novel antioestrogens without partial agonist activity
    • Wakeling AE, Bowler J. Novel antioestrogens without partial agonist activity. J Steroid Biochem 1988; 31: 645-653.
    • (1988) J Steroid Biochem , vol.31 , pp. 645-653
    • Wakeling, A.E.1    Bowler, J.2
  • 12
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • Wakeling AE, Dukes M, Bowler J. A potent specific pure antiestrogen with clinical potential. Cancer Res 1991; 51: 3867-3873.
    • (1991) Cancer Res , vol.51 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 14
    • 0025084510 scopus 로고
    • Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164,384 appears to be mediated by impaired receptor dimerization
    • Fawell SE, White R, Hoare S, Sydenham M, Page M, Parker MG. Inhibition of estrogen receptor-DNA binding by the "pure" antiestrogen ICI 164, 384 appears to be mediated by impaired receptor dimerization. Proc Natl Acad Sci USA 1990; 87: 6883-6887.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6883-6887
    • Fawell, S.E.1    White, R.2    Hoare, S.3    Sydenham, M.4    Page, M.5    Parker, M.G.6
  • 15
    • 0027768899 scopus 로고
    • The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling
    • Dauvois S, White R, Parker MG. The antiestrogen ICI 182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J Cell Sci 1993; 106: 1377-1388.
    • (1993) J Cell Sci , vol.106 , pp. 1377-1388
    • Dauvois, S.1    White, R.2    Parker, M.G.3
  • 16
    • 0033305525 scopus 로고    scopus 로고
    • Comparative analyses of mechanistic differences among antiestrogens
    • Wijayaratne AL, Nagel SC, Paige LA, et al. Comparative analyses of mechanistic differences among antiestrogens. Endocrinology 1999; 140: 5828-5840.
    • (1999) Endocrinology , vol.140 , pp. 5828-5840
    • Wijayaratne, A.L.1    Nagel, S.C.2    Paige, L.A.3
  • 17
    • 1242338758 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells
    • Frasor J, Stossi F, Danes JM, Komm B, Lyttle CR, Katzenellenbogen BS. Selective estrogen receptor modulators: Discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells. Cancer Res 2004; 64: 1522-1533.
    • (2004) Cancer Res , vol.64 , pp. 1522-1533
    • Frasor, J.1    Stossi, F.2    Danes, J.M.3    Komm, B.4    Lyttle, C.R.5    Katzenellenbogen, B.S.6
  • 18
    • 0029075872 scopus 로고
    • Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer
    • Osborne CK, Coronado-Heinsohn EB, Hilsenbeck SG, et al. Comparison of the effects of a pure steroidal antiestrogen with those of tamoxifen in a model of human breast cancer. J Natl Cancer Inst 1995; 87: 746-750.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 746-750
    • Osborne, C.K.1    Coronado-Heinsohn, E.B.2    Hilsenbeck, S.G.3
  • 19
    • 33751080415 scopus 로고    scopus 로고
    • Pure oestrogen antagonists for the treatment of advanced breast cancer
    • Howell A. Pure oestrogen antagonists for the treatment of advanced breast cancer. Endocr Relat Cancer 2006; 13: 689-706.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 689-706
    • Howell, A.1
  • 20
    • 0037102121 scopus 로고    scopus 로고
    • Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment
    • Howell A, Robertson JF, Quaresma Albano J, et al. Fulvestrant, formerly ICI 182, 780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. J Clin Oncol 2002; 20: 3396-3403.
    • (2002) J Clin Oncol , vol.20 , pp. 3396-3403
    • Howell, A.1    Robertson, J.F.2    Quaresma Albano, J.3
  • 21
    • 0037102126 scopus 로고    scopus 로고
    • Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial
    • Osborne CK, Pippen J, Jones SE, et al. Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: Results of a North American trial. J Clin Oncol 2002; 20: 3386-3395.
    • (2002) J Clin Oncol , vol.20 , pp. 3386-3395
    • Osborne, C.K.1    Pippen, J.2    Jones, S.E.3
  • 22
    • 0035884408 scopus 로고    scopus 로고
    • Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer
    • Robertson JF, Nicholson RI, Bundred NJ, et al. Comparison of the short-term biological effects of 7alpha-[9-(4, 4, 5, 5, 5-pentafluoropentylsulfinyl)-nonyl]estra-1, 3, 5, (10)-triene-3, 17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. Cancer Res 2001; 61: 6739-6746.
    • (2001) Cancer Res , vol.61 , pp. 6739-6746
    • Robertson, J.F.1    Nicholson, R.I.2    Bundred, N.J.3
  • 23
    • 77949621056 scopus 로고    scopus 로고
    • Enhanced resistance to Tamoxifen by the c-ABL proto-oncogene in breast cancer
    • Zhao H, Ou-Yang F, Chen IF, et al. Enhanced resistance to Tamoxifen by the c-ABL proto-oncogene in breast cancer. Neoplasia (New York, NY) 2010; 12: 214-223.
    • (2010) Neoplasia (New York, NY) , vol.12 , pp. 214-223
    • Zhao, H.1    Ou-Yang, F.2    Chen, I.F.3
  • 24
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou T-C. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 2006; 58: 621-681.
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.-C.1
  • 25
    • 0028181873 scopus 로고
    • Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites
    • Ren R, Ye ZS, Baltimore D. Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites. Genes Dev 1994; 8: 783-795.
    • (1994) Genes Dev , vol.8 , pp. 783-795
    • Ren, R.1    Ye, Z.S.2    Baltimore, D.3
  • 26
    • 77950633401 scopus 로고    scopus 로고
    • New strategies in estrogen receptor-positive breast cancer
    • Johnston SR. New strategies in estrogen receptor-positive breast cancer. Clin Cancer Res 2010; 16: 1979-1987.
    • (2010) Clin Cancer Res , vol.16 , pp. 1979-1987
    • Johnston, S.R.1
  • 27
    • 66249119060 scopus 로고    scopus 로고
    • Loss of phosphatase and tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer
    • Miller TW, Perez-Torres M, Narasanna A, et al. Loss of phosphatase and tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer. Cancer Res 2009; 69: 4192-4201.
    • (2009) Cancer Res , vol.69 , pp. 4192-4201
    • Miller, T.W.1    Perez-Torres, M.2    Narasanna, A.3
  • 28
    • 59449093537 scopus 로고    scopus 로고
    • Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant
    • Frogne T, Benjaminsen R, Sonne-Hansen K, et al. Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant. Breast Cancer Res Treat 2009; 114: 263-275.
    • (2009) Breast Cancer Res Treat , vol.114 , pp. 263-275
    • Frogne, T.1    Benjaminsen, R.2    Sonne-Hansen, K.3
  • 29
    • 0034987631 scopus 로고    scopus 로고
    • Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex)
    • McClelland RA, Barrow D, Madden TA, et al. Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182, 780 (Faslodex). Endocrinology 2001; 142: 2776-2788.
    • (2001) Endocrinology , vol.142 , pp. 2776-2788
    • McClelland, R.A.1    Barrow, D.2    Madden, T.A.3
  • 30
    • 33846207899 scopus 로고    scopus 로고
    • Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant
    • Fan M, Yan PS, Hartman-Frey C, et al. Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer Res 2006; 66: 11954-11966.
    • (2006) Cancer Res , vol.66 , pp. 11954-11966
    • Fan, M.1    Yan, P.S.2    Hartman-Frey, C.3
  • 31
    • 55449137556 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells
    • Oh AS, Lahusen JT, Chien CD, et al. Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells. Mol Cell Biol 2008; 28: 6580-6593.
    • (2008) Mol Cell Biol , vol.28 , pp. 6580-6593
    • Oh, A.S.1    Lahusen, J.T.2    Chien, C.D.3
  • 32
    • 0037420192 scopus 로고    scopus 로고
    • Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer
    • Osborne CK, Bardou V, Hopp TA, et al. Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. J Natl Cancer Inst 2003; 95: 353-361.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 353-361
    • Osborne, C.K.1    Bardou, V.2    Hopp, T.A.3
  • 33
    • 77951081069 scopus 로고    scopus 로고
    • c-Abl regulates estrogen receptor [alpha] transcription activity through its stabilization by phosphorylation
    • He X, Zheng Z, Song T, et al. c-Abl regulates estrogen receptor [alpha] transcription activity through its stabilization by phosphorylation. Oncogene 2010; 29: 2238-2251.
    • (2010) Oncogene , vol.29 , pp. 2238-2251
    • He, X.1    Zheng, Z.2    Song, T.3
  • 34
    • 0028833473 scopus 로고
    • Phosphorylation of the human estrogen receptor on tyrosine 537 in vivo and by src family tyrosine kinases in vitro
    • Arnold SF, Obourn JD, Jaffe H, Notides AC. Phosphorylation of the human estrogen receptor on tyrosine 537 in vivo and by src family tyrosine kinases in vitro. Mol Endocrinol 1995; 9: 24-33.
    • (1995) Mol Endocrinol , vol.9 , pp. 24-33
    • Arnold, S.F.1    Obourn, J.D.2    Jaffe, H.3    Notides, A.C.4


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