Prevalence of MEFV gene mutations and their clinical correlations in Turkish children with Henoch-Schönlein purpura

Acta Paediatrica, International Journal of Paediatrics

Volumn 100, Issue 5, 2011, Pages 745-749

  Bayram, Cengiz ^a   Demircin, Gülay ^b   Erdoǧan, Özlem ^a   Bülbül, Mehmet ^a   Çaltik, Aysun ^a   Akyüz, Sare G ^a  

^a DR SAMI ULUS CHILDREN S HOSPITAL   (Turkey)

^b AFYON KOCATEPE UNIVERSITY   (Turkey)

Author keywords

Familial Mediterranean fever; Henoch Sch nlein purpura; MEFV gene mutations

Indexed keywords

C REACTIVE PROTEIN; COLCHICINE; IMMUNOGLOBULIN A;

ANAPHYLACTOID PURPURA; ARTICLE; CHILD; DISEASE PREDISPOSITION; EARLY DIAGNOSIS; ERYTHROCYTE SEDIMENTATION RATE; FAMILIAL MEDITERRANEAN FEVER; FEMALE; GENE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC CODE; HETEROZYGOSITY; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEFV GENE; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; TURKEY (REPUBLIC);

CHILD; CHILD, PRESCHOOL; CYTOSKELETAL PROTEINS; FAMILIAL MEDITERRANEAN FEVER; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE DETECTION; HUMANS; MALE; MUTATION; PURPURA, SCHOENLEIN-HENOCH; TURKEY;

EID: 79953801998     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2011.02143.x     Document Type: Article

References (23)

1. Saulsbury F,. Henoch-Schönlein purpura in children. Medicine 1999; 78: 395-409.
2. Saulsbury FT,. Clinical update: Henoch-Schönlein purpura. Lancet 2007; 369: 976-8.
3. Dillon MJ,. Henoch-Schönlein purpura: recent advances. Clin Exp Rheumatol 2007; 25: S66-8.
4. Flatau E, Khon D, Schiller D, Lurie M, Levy E,. Schönlein-Henoch syndrome in patients with familial Mediterranean fever. Arthritis Rheum 1982; 25: 42-7. (Pubitemid 12215967)
5. Schlesinger M, Rubinow A, Vardy PA,. Henoch-Schönlein purpura and familial Mediterranean Fever. Isr J Med Sci 1985; 21: 83-5.
6. Gershoni-Baruch R, Broza Y, Brik R,. Prevalence and significance of mutations in the familial Mediterranean fever gene in Henoch-Schönlein purpura. J Pediatr 2003; 143: 658-61. (Pubitemid 37452797)
7. Ozdogan H, Arisoy N, Kasapçapur O, Sever L, Çalişkan S, Mat C, et al., Vasculitis in familial Mediterranean fever. J Rheumatol 1997; 24: 323-7. (Pubitemid 27104097)
8. Langevitz P, Zemer D, Livneh A, Shemer J, Pras M,. Protracted febrile myalgia in patients with familial Mediterranean fever. J Rheumatol 1994; 21: 1708-9. (Pubitemid 24285488)
9. Tekin M, Yalçinkaya F, Tumer N, Akar N, Misirlioǧlu M, Çakar N,. Clinical, laboratory and molecular characteristics of children with familial Mediterranean fever-associated vasculitis. Acta Paediatr 2000; 89: 177-82. (Pubitemid 30339589)
10. Lange-Sperandino B, Möhrig K, Gutzler F, Mehls O,. Variable expression of vasculitis in siblings with familial Mediterranean fever. Pediatr Nephrol 2004; 19: 539-43. (Pubitemid 38594294)
11. Tunca M, Akar S, Onen F, özdoǧan H, Kaspçopur O, Yalçinkaya F, et al., Familial Mediterranean Fever (FMF) in Turkey: results of a nationwide study. Medicine 2005; 84: 1-11. (Pubitemid 40130180)
12. Yalçinkaya F, özçakar ZB, Kasapçopur ö, öztürk A, Akar N, Bakkaloǧlu A, et al., Prevalence of the MEFV gene mutations in childhood polyarteritis nodosa. J Pediatr 2007; 151: 675-8. (Pubitemid 350116122)
13. özçakar ZB, Yalçinkaya F, Çakar N, Acar B, Kasapçopur O, Ugüten D, et al., MEFV mutations modify the clinical presentation of Henoch-Schönlein purpura. J Rheumatol 2008; 35: 2427-9.
14. Imirzalioǧlu N, Dursun A, Tastan B, Soysal Y, Yakicier MC,. MEFV gene is a probable susceptibility gene for Behçet's disease. Scand J Rheumatol 2005; 34: 56-8. (Pubitemid 40445060)
15. Giaglis S, Mimidis K, Papadopoulos V, Thomopoulos K, Sidiropoulos P, Rafail S, et al., Increased frequency of mutations in the gene responsible for Familial Mediterranean Fever (MEFV) in a cohort of patients with ulcerative colitis: evidence for a potential disease-modifying effect? Dig Dis Sci 2006; 51: 687-92.
16. Yilmaz E, Ozen S, Balci B, Düzova A, Topaloǧlu R, Beşbaş N, et al., Mutation frequency of familial Mediterranean fever and evidence for a high carrier rate in the Turkish population. Eur J Hum Genet 2001; 9: 553-5. (Pubitemid 32750497)
17. Rabinovich E, Livneh A, Langevitz P, Brezniak N, Shinar E, Pras M, et al., Severe disease in patients with rheumatoid arthritis carrying a mutation in the Mediterranean fever gene. Ann Rheum Dis 2005; 64: 1009-14. (Pubitemid 40909514)
18. Fidder H, Chowers Y, Ackerman Z, Pollak RD, Crusius JB, Livneh A, et al., The familial Mediterranean fever (MEFV) gene as a modifier of Crohn's disease. Am J Gastroenterol 2005; 100: 338-43. (Pubitemid 40314518)
19. Ozen S, Karaaslan Y, Ozdemir O, Saatçi U, Bakkaloǧlu A, Koroǧlu E, et al., Prevalence of juvenile chronic arthritis and familial Mediterranean fever in Turkey: a field study. J Rheumatol 1998; 25: 2445-9. (Pubitemid 28551865)
20. Olgun A, Akman S, Kurt I, Tuzun A, Kutluay T,. MEFV mutations in familial Mediterranean fever: association of M694V homozygosity with arthritis. Rheumatol Int 2005; 25: 255-9. (Pubitemid 40767828)
21. Tunca M, Kirkali G, Soytürk M, Akar S, Pepys MB, Hawkins PN,. Acute phase response and evolution of familial Mediterranean fever. Lancet 1999; 353: 1415. (Pubitemid 29192423)
22. Ozen S, Bakkaloglu A, Yilmaz E, Düzova A, Balci B, Topaloǧlu R, et al., Mutations in the gene for familial Mediterranean fever: do they predispose to inflammation? J Rheumatol 2003; 30: 2014-8. (Pubitemid 37075554)
23. Lachmann HJ, Sengül B, Yavuzsen TU, Booth Dr, Booth SE, Bybee A, et al., Clinical and subclinical inflammation in patients with familial Mediterranean fever and in heterozygous carriers of MEFV mutations. Rheumatology (Oxford) 2006; 45: 746-50. (Pubitemid 43985345)