Down-regulation of vascular endothelial growth factor and up-regulation of pigment epithelium derived factor make low molecular weight heparin-endostatin and polyethylene glycol-endostatin potential candidates for anti-angiogenesis drug

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 4, 2011, Pages 545-550

  Tan, Haining ^a   Mu, Guoying ^a   Zhu, Wei ^a   Liu, Jinfeng ^a,b   Wang, Fengshan ^a  

^a SHANDONG UNIVERSITY   (China)

^b QUFU NORMAL UNIVERSITY   (China)

Author keywords

Choroidal neovascularization; Endostatin; Low molecular weight heparin endostatin; Polyethylene glycol endostatin; Zebrafish

Indexed keywords

ANGIOGENESIS INHIBITOR; ENDOSTATIN; ENDOSTATIN PLUS LOW MOLECULAR WEIGHT HEPARIN; ENDOSTATIN PLUS MACROGOL; LOW MOLECULAR WEIGHT HEPARIN; MACROGOL; PIGMENT EPITHELIUM DERIVED FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CHEMICAL MODIFICATION; CHOROID; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SUBRETINAL NEOVASCULARIZATION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; ZEBRA FISH;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL PROLIFERATION; CHOROIDAL NEOVASCULARIZATION; ENDOSTATINS; ENDOTHELIAL CELLS; EYE PROTEINS; HEPARIN, LOW-MOLECULAR-WEIGHT; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; NERVE GROWTH FACTORS; POLYETHYLENE GLYCOLS; SERPINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH;

EID: 79953798602     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.545     Document Type: Article

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