Prolonged lymphopenia in a patient with lymphoma and severe Pandemic influenza A H1N1 2009 virus infection

Influenza and other Respiratory Viruses

Volumn 5, Issue 3, 2011, Pages 167-169

  Ñamendys Silva, Silvio A ^a   Pérez Jiménez, Carolina ^a   Cornejo Juárez, Patricia ^a   Vilar Compte, Diana ^a   Volkow, Patricia ^a  

^a INSTITUTO NACIONAL DE CANCEROLOGÍA   (Mexico)

Author keywords

Immunocompromised patient; Lymphopenia; Pandemic influenza A H1N1 2009

Indexed keywords

CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; OSELTAMIVIR; RIMANTADINE; VINCRISTINE;

ADOLESCENT; ANTIVIRAL THERAPY; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CANCER CHEMOTHERAPY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DETERIORATION; HUMAN; IMMUNOCOMPROMISED PATIENT; INFLUENZA VIRUS A H1N1; LYMPHOBLASTOMA; LYMPHOCYTOPENIA; MALE; MULTIPLE CYCLE TREATMENT; PANDEMIC INFLUENZA; PRIORITY JOURNAL; RESPIRATORY FAILURE; THORAX RADIOGRAPHY;

ADOLESCENT; ANTIVIRAL AGENTS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LYMPHOMA; LYMPHOPENIA; MALE; OSELTAMIVIR;

EID: 79953779798     PISSN: 17502640     EISSN: 17502659     Source Type: Journal    
DOI: 10.1111/j.1750-2659.2010.00193.x     Document Type: Article

References (8)

1. Pérez-Padilla R, de la Rosa-Zamboni D, Ponce de León S et al. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med 2009; 361:680-689.
2. Fleming DM, Zambon M. Update on influenza and other viral pneumonias. Curr Opin Infect Dis 2001; 14:199-204.
3. Gooskens J, Jonges M, Claas EC, Meijer A, Kroes AC. Prolonged influenza virus infection during lymphocytopenia and frequent detection of drug-resistant viruses. J Infect Dis 2009; 199:1435-1441.
4. Nichols WG, Guthrie KA, Corey L, Boeckh M. Influenza infections after hematopoietic stem cell transplantation: risk factors, mortality, and the effect of antiviral therapy. Clin Infect Dis 2004; 39:1300-1306.
5. Mumcuoglu M, Zakay-Rones Z, Weiss L, Slavin S. The effect of total or partial lymphocyte depletion on susceptibility to influenza virus infection and development of antiviral immunity in lethally irradiated mice reconstituted with immune syngeneic bone marrow grafts. Bone Marrow Transplant 1991; 7:217-220.
6. Gabriel G, Klingel K, Planz O et al. Spread of infection and lymphocyte depletion in mice depends on polymerase of influenza virus. Am J Pathol 2009; 175:178-186.
7. Casper C, Englund J, Boeckh M. How I treat influenza in patients with hematologic malignancies. Blood 2010; 7:1331-1342.
8. World Health Organization. Clinical management of human infection with pandemic (H1N1) 2009: revised guidance. Geneva: World Health Organization, November 2009. Available at (Accessed 26 July 2010).