Pharmacokinetics, safety, and tolerability following multiple oral doses of varenicline under various titration schedules in elderly nonsmokers

Journal of Clinical Pharmacology

Volumn 51, Issue 4, 2011, Pages 492-501

  Zhao, Qinying ^a   Schwam, Elias ^a   Fullerton, Terence ^a   O'Gorman, Melissa ^a   Burstein, Aaron H ^a  

^a PFIZER INC   (United States)

Author keywords

Elderly; Multiple dose pharmacokinetics; Nonsmokers; Varenicline

Indexed keywords

PLACEBO; VARENICLINE;

ABDOMINAL PAIN; AGED; ANXIETY; AREA UNDER THE CURVE; ARTHRALGIA; ARTICLE; CONSTIPATION; DIARRHEA; DIZZINESS; DRUG BLOOD LEVEL; DRUG DOSE TITRATION; DRUG ELIMINATION; DRUG ERUPTION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG SAFETY; DRUG TOLERABILITY; DYSURIA; FATIGUE; FEMALE; HEART VENTRICLE EXTRASYSTOLE; HERPES ZOSTER; HOT FLUSH; HUMAN; HYPERTENSION; INFLUENZA; JOINT SWELLING; KIDNEY FUNCTION; MALE; MUSCULOSKELETAL PAIN; NAUSEA; NORMAL HUMAN; PAIN; POPULATION; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; SIDE EFFECT; SINGLE BLIND PROCEDURE; SKIN DEFECT; SKIN INFLAMMATION; SMOKING; SMOKING CESSATION; STEADY STATE; UPPER RESPIRATORY TRACT INFECTION; VOMITING;

ADMINISTRATION, ORAL; AGED; BENZAZEPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HALF-LIFE; HUMANS; MALE; NICOTINIC AGONISTS; PLACEBOS; QUINOXALINES; SINGLE-BLIND METHOD;

EID: 79953776835     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270010370461     Document Type: Article

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