Antigen-Specific IgG ameliorates allergic airway inflammation via Fcγ receptor IIB on dendritic cells

Respiratory Research

Volumn 12, Issue , 2011, Pages

  Ishikawa, Yumiko ^a   Kobayashi, Kazuyuki ^a   Yamamoto, Masatsugu ^a   Nakata, Kyosuke ^a   Takagawa, Tetsuya ^a   Funada, Yasuhiro ^a   Kotani, Yoshikazu ^a   Karasuyama, Hajime ^b   Yoshida, Masaru ^a   Nishimura, Yoshihiro ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR IIB; FLUORESCEIN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; OVALBUMIN; FC RECEPTOR; FCGR2B PROTEIN, MOUSE; IMMUNOGLOBULIN G;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; ASTHMA; BONE MARROW CELL; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DENDRITIC CELL; EOSINOPHIL; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HISTOPATHOLOGY; IN VITRO STUDY; LUNG LAVAGE; MOUSE; NONHUMAN; ANIMAL; BRONCHUS HYPERREACTIVITY; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; GENETICS; IMMUNOLOGY; LYMPH NODE; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; TH2 CELL; TRANSPLANTATION;

ANIMALS; ANTIGENS, CD11C; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; FLOW CYTOMETRY; IMMUNOGLOBULIN G; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; OVALBUMIN; RECEPTORS, IGG; TH2 CELLS;

EID: 79953756092     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-12-42     Document Type: Article

References (41)

1. Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004, 59:469-478. 10.1111/j.1398-9995.2004.00526.x, 15080825.
2. Kinet JP. The high-affinity IgE receptor (Fc epsilon RI): from physiology to pathology. Annu Rev Immunol 1999, 17:931-972. 10.1146/annurev.immunol.17.1.931, 10358778.
3. Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999, 17:255-281. 10.1146/annurev.immunol.17.1.255, 10358759.
4. Avila PC. Does anti-IgE therapy help in asthma? Efficacy and controversies. Annu Rev Med 2007, 58:185-203. 10.1146/annurev.med.58.061705.145252, 17059361.
5. Strunk RC, Bloomberg GR. Omalizumab for asthma. N Engl J Med 2006, 354:2689-2695. 10.1056/NEJMct055184, 16790701.
6. Hanania NA. Targeting airway inflammation in asthma: current and future therapies. Chest 2008, 133:989-998. 10.1378/chest.07-0829, 18398119.
7. Ogra PL, Faden H, Welliver RC. Vaccination strategies for mucosal immune responses. Clin Mivrobiol Rev 2001, 14:430-445.
8. Miyagawa N, Iwasaki H, Kato T, Tanaka M, Shibata T, Wakitani K. Induction of late airway response was involved in serum antigen-specific immunoglobulin G in rats. Int Immunopharmacol 2008, 8:1848-1853. 10.1016/j.intimp.2008.09.003, 18822391.
9. Platts-Mills T, Vaughan J, Squillace S, Woodfolk J, Sporik R. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 2001, 357:752-756. 10.1016/S0140-6736(00)04168-4, 11253969.
10. Aalberse RC, van der Gaag R, van Leeuwen J. Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response. J Immunol 1983, 130:722-726.
11. Ravetch JV, Kinet JP. Fc receptors. Annu Rev Immunol 1991, 9:457-492. 10.1146/annurev.iy.09.040191.002325, 1910686.
12. Takai T. Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2002, 2:580-592.
13. Hulett MD, Hogarth PM. Molecular basis of Fc receptor function. Adv Immunol 1994, 57:1-127.
14. Masuda A, Yoshida M, Shiomi H, Morita Y, Kutsumi H, Inokuchi H, Mizuno S, Nakamura A, Takai T, Blumberg RS, Azuma T. Role of Fc Receptors as a therapeutic target. Inflamm Allergy Drug Targets 2009, 8:80-86. 10.2174/187152809787582525, 19275696.
15. Masuda A, Yoshida M, Shiomi H, Ikezawa S, Takagawa T, Tanaka H, Chinzei R, Ishida T, Morita Y, Kutsumi H, Inokuchi H, Wang S, Kobayashi K, Mizuno S, Nakamura A, Takai T, Blumberg RS, Azuma T. Fcgamma receptor regulation of Citrobacter rodentium infection. Infect Immun 2008, 76:1728-1737. 10.1128/IAI.01493-07, 2292883, 18227164.
16. Nimmerjahn F, Ravetch JV. Fcgamma receptors: old friends and new family members. Immunity 2006, 24:19-28. 10.1016/j.immuni.2005.11.010, 16413920.
17. McGaha TL, Sorrentino B, Ravetch JV. Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science 2005, 307:590-593. 10.1126/science.1105160, 15681388.
18. Qiu WQ, de Bruin D, Brownstein BH, Pearse R, Ravetch JV. Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination. Science 1990, 248:732-735. 10.1126/science.2139735, 2139735.
19. Lambrecht BN, Hammad H. Taking our breath away: dendritic cells in the pathogenesis of asthma. Nat Rev Immunol 2003, 3:994-1003. 10.1038/nri1249, 14647481.
20. Lambrecht BN. Allergen uptake and presentation by dendritic cells. Curr Opin Allergy Clin Immunol 2001, 1:51-59.
21. Van Rijt LS, Jung S, KleinJan A, Vos N, Willart M, Duez C, Hoogsteden HC, Lambrecht BN. In vivo depletion of lung CD11c dendritic cells during allergen challenge abrogates the characteristic features of asthma. JEM 2005, 201:981-991.
22. Kitamura K, Takeda K, Koya T, Miyahara N, Kodama T, Dakhama A, Takai T, Hirano A, Tanimoto M, Harada M, Gelfand EW. Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation. J Immunol 2007, 178:480-488.
23. Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV. Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 1996, 379:346-349. 10.1038/379346a0, 8552190.
24. Barnden MJ, Allison J, Heath WR, Carbone FR. Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements. Immunol Cell Biol 1998, 76:34-40. 10.1046/j.1440-1711.1998.00709.x, 9553774.
25. Ishikawa R, Tsujimura Y, Obata K, Kawano Y, Minegishi Y, Karasuyama H. IgG-mediated systemic anaphylaxis to protein antigen can be induced even under conditions of limited amounts of antibody and antigen. BBRC 2010, 402:742-746.
26. Renz H, Saloga J, Bradley KL, Loader JE, Greenstein JL, Larsen G, Gelfand EW. Specific V beta T cell subsets mediate the immediate hypersensitivity response to ragweed allergen. J Immunol 1993, 151:1907-1917.
27. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 1997, 156:766-775.
28. Vermaelen KY, Carro-Muino I, Lambrecht BN, Pauwels RA. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. JEM 2001, 193:51-60.
29. Inaba K, Inaba M, Romani N, Aya H, Deguchi M, Ikehara S, Muramatsu S, Steinman RM. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 1992, 176:1693-1702. 10.1084/jem.176.6.1693, 2119469, 1460426.
30. Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, Romani N, Schuler G. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 1999, 223:77-92. 10.1016/S0022-1759(98)00204-X, 10037236.
31. Ishiyama M, Miyazono Y, Sasamoto K, Ohkura Y, Ueno K. A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability. Talanta 1997, 44:1299-1305. 10.1016/S0039-9140(97)00017-9, 18966866.
32. Sato K, Fujita S. Dendritic cells: nature and classification. Allergol Int 2007, 56:183-191. 10.2332/allergolint.R-06-139, 17646733.
33. Bayry J, Lacroix-Desmazes S, Carbonneil C, Misra N, Donkova V, Pashov A, Chevailler A, Mouthon L, Weill B, Bruneval P, Kazatchkine MD, Kaveri SV. Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin. Blood 2003, 101:758-765. 10.1182/blood-2002-05-1447, 12393386.
34. Boruchov AM, Heller G, Veri MC, Bonvini E, Ravetch JV, Young JW. Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions. J Clin Invest 2005, 115:2914-2923. 10.1172/JCI24772, 1201664, 16167082.
35. Hartwig C, Mazzega M, Constabel H, Krishnaswamy JK, Gessner JE, Braun A, Tschernig T, Behrens GM. Fcgamma receptor-mediated antigen uptake by lung DC contributes to allergic airway hyper-responsiveness and inflammation. Eur J Immunol 2010, 40:1284-1295. 10.1002/eji.200939900, 20148421.
36. Akiyama K, Ebihara S, Yada A, Matsumura K, Aiba S, Nukiwa T, Takai T. Targeting apoptotic tumor cells to Fc gamma R provides efficient and versatile vaccination against tumors by dendritic cells. J Immunol 2003, 170:1641-1648.
37. Liu Y, Gao X, Masuda E, Redecha PB, Blank MC, Pricop L. Regulated expression of FcgammaR in human dendritic cells controls cross-presentation of antigen-antibody complexes. J Immunol 2006, 177:8440-8447.
38. Dharajiya N, Vaidya SV, Murai H, Cardenas V, Kurosky A, Boldogh I, Sur SA. FcgammaRIIb inhibits allergic lung inflammation in a murine model of allergic asthma. PLoS One 2010, 5:e9337. 10.1371/journal.pone.0009337, 2825267, 20179765.
39. Yamamoto M, Kobayashi K, Ishikawa Y, Nakata K, Funada Y, Kotani Y, Masuda A, Takai T, Azuma T, Yoshida M, Nishimura Y. The inhibitory effects of intravenous administration of rabbit IgG on airway inflammation are dependent on Fcγ receptor IIb on CD11c+ dendritic cells in murine model. Clin Exp Immunol 2010, 162:315-324. 10.1111/j.1365-2249.2010.04243.x, 20819092.
40. Sehra S, Pynaert G, Tournoy K, Haegeman A, Matthys P, Tagawa Y, Pauwels R, Grooten J. Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on Fc gamma R and IFN-gamma. J Immunol 2003, 171:2080-2089.
41. Lambrecht BN, Veerrman MD, Coyle AJ, Gutierrez-Ramos JC, Thielemans K, Pauwels RA. Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation. J Clin Invest 2000, 106:551-559. 10.1172/JCI8107, 380243, 10953030.