Hypoglycaemic and coronary risk index lowering effects of Bauhinia thoningii in alloxan induced diabetic rats

African Health Sciences

Volumn 11, Issue 1, 2011, Pages 85-89

  Ojezele, Matthew Obaineh ^a   Abatan, O M ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Bauhinia thoningii; Coronary risk index; Diabetes

Indexed keywords

ANTIDIABETIC AGENT; BAUHINIA THONINGII EXTRACT; GLIBENCLAMIDE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAUHINIA; BAUHINIA THONINGII; BLOOD GLUCOSE MONITORING; BLOOD SAMPLING; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY RISK; DIABETES MELLITUS; DOWN REGULATION; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; FEMALE; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; LIPID COMPOSITION; MALE; NONHUMAN; PLANT LEAF; RAT; RISK ASSESSMENT; RISK REDUCTION;

ADMINISTRATION, ORAL; ALLOXAN; ANIMALS; BAUHINIA; BLOOD GLUCOSE; CARDIOVASCULAR DISEASES; CHOLESTEROL, LDL; DIABETES MELLITUS, EXPERIMENTAL; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; LIPID METABOLISM; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; RISK; TRIGLYCERIDES;

EID: 79953740923     PISSN: 16806905     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27 (5): 1047-1053
2. nd Edition. Pearson Education Limited, UK. 606, 2007.
3. Giugliano, D., Ceriello A. Oxidative stress and diabetic vascular complications Diabetes Care 1996; 19:257-267
4. Day, C., Bailey C.J. A diabetologist's herbal. In Current Medical Literature-Diabetes 5: 31-35. H Keen and P Lefebvre, editors. London: Royal Society of Medicine, 1988
5. U.K. Prospective Diabetes Study Group. Perspectives in Diabetes. U.K. Prospective Diabetes Study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease. Diabetes 1995; 44: 1249-1258
6. Jack, W. Reich, Research. Remington: The Science and Practice of Pharmacy. (19th edn) 1:52-59, 1995.
7. World Health Organisation. WHO guidelines on good agricultural and collection practices (GACP) for medicinal plants. World Health Organization, Geneva, 2003.
8. Baumer, M. Notes on Trees and Shrubs in Arid and Semi-arid Regions. FAO/UNEP Programme "Ecological Management of Arid and Semi-Arid Rangelands in Africa, Near and Middle East" (EMASAR Phase II). 270p, 1983.
9. Rajesh, KG., Mohinder, PM., Shrinivas, KK. Evaluation of antihyperglycaemic activity of some novel monocyclic beta lactams. J. Pharm. Pharmacet. Sci. 2004; 7 (1):80-83.
10. Nagappa, AN., Thakurdesai, PA., Venket Rao, N., Singh J. Antidiabetic activity of Terminalia catappa Linn fruits. Journal of Ethnopharmacol. 2003; 88:45-50.
11. Friedewald, WT., Levy, RI., Fredrickson, DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem.1972; 18:499
12. rd ed Stuttgart/New York: Schattauer,1995.
13. Ishiguro T, Seki M, Yokota M. Coronary risk index for preoperative evaluation of ischemic heart disease. Masui. 1995; 44:51-59.
14. Seki M, Ishiguro T, Gyouda Y. Evaluation of the efficacy of coronary risk index, a new scoring system for predicting morbidity and severity of coronary stenosis in patients undergoing coronary angiography. J Jpn Soc Clin Anesth. 1998; 18:271-276.
15. Gidado, A., Ameh, DA. and Atawodi SE. Effects of Nuclea ratifolia leaves aqueous extracts on blood glucose levels of normal and alloxan-induced diabetic rats. African Journal of Biotechnology 2004; 4 (1): 91-93.
16. Nimenibo U. Effects of aqueous extract of Canavalia ensiformis seeds on hyperlipidaemia and hyperketonaemia in alloxan-induced diabetic rats. NISEB. 2003; 15 (1): 7-15.
17. Bansal R., Ahmandu R., Kiduai SR. Alloxan-glucose interaction. Effect of incorporation of 14 C-leucine into pancreatic islets of rats. Acta. Diabetol. Lat. 1980; 17:13-143.
18. Aderibigbe AO, Emudianughe TS, Lawal BAS. Antihyperglycaemic effects of Mangifera indica in rats. Phytother. 1999; 13:504-507
19. Emudianughe TS, Aderibigbe AO. The hypoglycaemic effect of Telfaria occidentalis aqueous leaf extract in rats. West Afr. J. Pharmacol. 2002; 18(1&2): 14-16
20. th edition. Pearson Education Australia.413-542, 2007.
21. Khan, A. Cinnamon Improves Glucose and Lipids of People With Type 2 Diabetes. Diabetes Care 2003; 26: 3215.
22. Stratton IM., Adler AI., Neil AW. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000; 3:405-412.
23. Davis TM., Cull CA., Holman RR. Relationship between ethnicity and glycaemic control, lipid profiles, and blood pressure during the first 9 years of type 2 diabetes: UK Prospective Diabetes Study (UKPDS 55). Diabetes Care 2001; 24:1167-74.