Changes in TIMP-1 and -2 expression in the early stage of porcine serum-induced liver fibrosis in rats

Experimental and Toxicologic Pathology

Volumn 63, Issue 4, 2011, Pages 357-361

  Hasegawa Baba, Yasuko ^a,b   Doi, Kunio ^a,b  

^a NIPPON INSTITUTE FOR BIOLOGICAL SCIENCE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Liver fibrosis; Porcine serum; Rat; TIMP 1; TIMP 2

Indexed keywords

MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN NORWAY RAT; CELL INFILTRATION; CONTROLLED STUDY; ENZYME BLOOD LEVEL; GENE EXPRESSION; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER LEVEL; MALE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; WISTAR RAT;

ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; LIVER CIRRHOSIS; MALE; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERUM; SWINE; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

RATTUS; RATTUS NORVEGICUS; SUS;

EID: 79953738528     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2010.02.011     Document Type: Article

References (40)

1. Abraham D., Ponticos M., Nagase H. Connective tissue remodeling: cross-talk betweenendothelins and matrix metalloproteinases. Curr Vasc Pharmacol 2005, 3:369-379.
2. Arthur M.J.P. Collagenases and liver fibrosis. J Hepatol 1995, 22:43-48.
3. Baba Y., Doi K. MHC class II-related genes expression in porcine-serum-induced rat hepatic fibrosis. Exp Mol Pathol 2004, 77:214-221.
4. Baba Y., Saeki K., Onodera T., Doi K. Serological and immunohistochemical studies on porcine-serum-induced hepatic fibrosis in rats. Exp Mol Pathol 2005, 79:229-235.
5. Baba Y., Uetsuka K., Nakayama H., Doi K. Rat strain differences in the early stage of porcine-serum-induced hepatic fibrosis. Exp Toxicol Pathol 2004, 55:325-330.
6. Bhunchet E., Eishi Y., Wake K. Contribution of immune response to the hepatic fibrosis induced by porcine serum. Hepatology 1996, 23:811-817.
7. Boeker K.H.W., Haberkorn C.I., Michel D., Flemming P., Manns M.P., Lichtinghagen R. Diagnostic potential of circulating TIMP-1 and MMP-2 as markers of liver fibrosis inpatients with chronic hepatitis C. Clin Chim Acta 2002, 316:71-81.
8. Chen F., Cai W., Chen Z., Chen X., Liu R. Dynamic changes in the collagen metabolism of liver fibrosis at the transcription level in rabbits with Schistosomiasis japonica. Chin Med J 2002, 115:1637-1640.
9. Doi K., Kurabe S., Shimazu N., Inagaki S. Systemic histopathology of rats with CCl4-induced hepatic fibrosis. Lab Anim 1991, 25:21-25.
10. Ebata M., Fukuda Y., Nakano I., Katano Y., Fujimoto N., Hayakawa T. Serum levels of tissue inhibitor of metalloproteinases-2 and of precursor form of matrix metalloproteinase-2 in patients with liver disease. Liver 1997, 17:293-299.
11. Elsebae M.M., Abu-Zekri N.B. A study of the effect of splenectomy on hepatic functional reserve and structural damage in patients with chronic hepatitis C virus infection by non-invasive serum markers. A prospective study. Int J Surg 2008, 6:362-366.
12. Fridman R., Fuerst T.R., Bird R.E., Hoyhtya M., Oelkuct M., Kraus S., Komarek D., Liotta L.A., Berman M.L., Stetler-Stevenson W.G. Domain structure of human 72-kDa gelatinase/type IV collagnase: characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-(TIMP-2) binding regions. J Biol Chem 1992, 267:15398-15405.
13. Garcia L., Hernandez I., Sandoval A., Salazar A., Garcia J., Vera J., Grijalva G., Muriel P., Margolin S., Armendariz-Bounda J. Pirfenidone effectively reverses experimental liver fibrosis. J Hepatol 2002, 37:797-805.
14. Geraci P., Mariano M.S., Jackson K.L. Radiation hepatology of the rat: microvascular fibrosis and enhancement of liver dysfunction by diet and drugs. Radiat Res 1992, 129:322-332.
15. Haczku A., Chung K.F., Sun J., Barnes P.J., Kay A.B., Moqbel R. Airway hyperresponsiveness, elevation of serum-specific IgE and activation of T cells following allergen exposure in sensitized Brown Norway rats. Immunology 1995, 85:598-603.
16. Herbst H., Wege T., Milani S., Pellegrini G., Orzechowski H.-D., Bechstein W.O., Neuhaus P., Fressner A.M., Schuppan D. Tissue inhibitor of metalloproteinase-1 and -2 RNA expressionIn rat and human liver fibrosis. Am J Pathol 1997, 150:1647-1659.
17. Hironaka K., Sakaida I., Matsumura Y., Kaino S., Miyamoto K., Okita K. Enhanced interstitial collagnase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis. Biochem Biophys Res Commun 2000, 267:290-295.
18. Howard E.W., Bullen E.C., Banda M.J. Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinase-2. J Biol Chem 1991, 266:13064-13069.
19. Kawai K., Uetsuka K., Doi K., Nakayama H. The activity of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in mammary tumors of dogs and rats. J Vet Med Sci 2006, 68:105-111.
20. Knittel T., Mehde M., Grundmann A., Saile B., Scharf J.-G., Ramadori G. Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat. Histochem Cell Biol 2000, 11:443-453.
21. Kossakowska A.E., Eward D.R., Lee S.S., Urbanski L.S., Stabbler A.L., Zhang C.-L., Phillips B.W., Zhang Y., Urbanski S.J. Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosis. Am J Pathol 1998, 153:1895-1902.
22. Leroy V., Monier F., Bottari S., Trome C., Sturm N., Hilleret N., Morel F., Zarski J.P. Circulating matrix metalloproteinases 1, 2, 9 and their inhibitors TIMP-1 and TIMP-2 as serum markers of liver fibrosis in patients with chronic hepatitis C: comparison with PIIINP and hyaluronic acid. Am J Gastroenterol 2004, 99:271-279.
23. Li J., Rosman A.S., Lio M.A., Nagai Y., Lieber C.S. Tissue inhibitor of metalloproteinases is increased in the serum of precirrhotic and cirrhotic alcoholic patients and can serve as a maker of fibrosis. Hepatology 1994, 19:1418-1423.
24. Mitsuda A., Suou T., Ikuta Y., Kawasaki H. Changes in serum tissue inhibitor of matrix metalloproteinase-1 after interferon alpha treatment in chronc hepatitis C. J Hepatol 2000, 32:666-672.
25. Murawaki Y., Ikuta Y., Okamoto K., Koda M., Kawasaki H. Diagnostic value of serum markers of connective tissue turnover for predicting histological staging and grading in patients with chronic hepatitis C. Gastroenterology 2001, 36:399-406.
26. Murawaki Y., Yamamoto H., Kawasaki H., Shima H. Serum tissue inhibitor of metalloproteinases I in patients with chronic liver disease and with hepatocellular carcinoma. Clin Chim Acta 1993, 218:47-48.
27. Nie Q.H., Zhang Y.F., Xie Y.M., Luo X.D., Shao B., Li J., Zhou Y.X. Correlation between TIMP-1 expression and liver fibrosis in two rat liver fibrosis models. World J Gastroenterol 2006, 12:3044-3049.
28. Ninomiya T., Yoon S., Nagano H., Kumon Y., Seo Y., Kasuga M., Yano, Nakaji M., Hayashi Y. Significance of serum matrix metalloproteinases and their inhibitors on the antifibrogenetic effect of interferon-alpha in chronic hepatitis C. Intervirology 2001, 44:227-231.
29. Parsons C.J., Bradford B.U., Pan C.Q., Cheung E., Schauer M., Knorr A., Krebs B., Kraft S., Zahn S., Brocks B., Feirt N., Mei B., Cho M.S., Ramamoorthi R., Roldan G., Ng P., Lum P., Hirth-Dietrich C., Tomkinson A., Brenner D.A. Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats. Hepatology 2004, 40:1106-1115.
30. Shiga A., Shirota K., Ikeda T., Nomura Y. Morphological and immunohistochemical studies on porcine serum-induced rat liver fibrosis. J Vet Med Sci 1997, 59:159-167.
31. Siller-Lopez F., Sandoval A., Salgado S., Salazar A., Bueno M., Carcia J., Vera J., Galvez J., Hernandez I., Ramos M., Aguilar-Cordova E., Armendariz-Borunda J. Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis. Gastroenterology 2004, 126:1122-1133.
32. Tani Y., Murata S., Kajikawa S., Mizuno H., Fukushige J., Hosokawa T., Uetsuka K., Nakayama H., Doi K. Rapid induction of liver cirrhosis in Mini rats by thioacetamide. J Toxicol Pathol 1998, 11:119-125.
33. Tsushima H., Kawata S., Tamura S., Ito N., Shirai Y., Kiso S., Doi Y., Yamada A., Oshikawa O., Matsuzawa Y. Reduced plasma transforming growth factor-beta1 levels in patients with chronic hepatiis C after interferon-alpha therapy: association with regression of hepatic fibrois. J Hepatol 1999, 30:1-7.
34. Uetsuka K., Suzuki M., Nakayama H., Doi K. Prolonged oval cell proliferation with Ito cell activation and extracellular matrix accumulation in galactosamine-induced acute hepatitis in Mini rats. Histol Histopathol 1997, 12:937-943.
35. Uyama O., Ihaku D., Kitada O., Miyasaka M., Sugita M. Role of eosinophils and cell adhesion molecules in the allergen-induced asthmatic response of rats. Res Commun Mol Pathol Pharmacol 1995, 90:3-15.
36. Vaillant B., Chiaramonte M.G., Cheever A.W., Soloway P.D., Wynn T.A. Regulation of hepatic fibrosis and extracellular matrix genes by the the response: new insight into the role of tissue inhibitors of matrix metalloproteinases. J Immunol 2001, 167:7017-7026.
37. RMAF WysZomirska, CCL Lacet, Tenorio L.R., Nishimura N.F., Mesquita M.A., Neto J.B., Oliveira F., MCLV Balwani, JRSA Almeida, Soares E.C. Decrease of type IV collagen and TIMP-1 serum levels after splenectomy in patients with Shistosomiasis mansoni. Acta Trop 2006, 97:301-308.
38. Xu G.F., Li P.T., Wang X.Y., Jia X., Tian D.L., Jiang L.D., Yang J.X. Dynamic changes in the expression of matrix metalloproteinases and their inhibitors, TIMPS, during hepatic fibrosis induced by alcohol in rats. World J Gastroenterol 2004, 10:3621-3627.
39. Yoshiji H., Kuriyama S., Yoshii J., Ikenaka Y., Noguchi R., Nakatani T., Tsujinoue H., Yanase K., Namisaka T., Imazu H., Fukui H. Tissue inhibitor of metalloproteinase-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse. Hepatology 2002, 36:850-860.
40. Zhang B.B., Cai W.M., Weng H.L., Hu Z.R., Lu J., Zheng M., Liu R.H. Diagnostic value of platelet derived growth factor-BB, transforming growth factor-beta1, matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinase-1 in serum and peripheral blood mononuclear cells from hepatic fibrosis. World J Gastroenterol 2003, 9:2490-2496.