Simultaneous gas chromatography-tandem mass spectrometry quantification of symmetric and asymmetric dimethylarginine in human urine

Analytical Biochemistry

Volumn 413, Issue 1, 2011, Pages 60-62

  Tsikas, Dimitrios ^a   Beckmann, Bibiana ^a   Gutzki, Frank Mathias ^a   Jordan, Jens ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MASS SPECTROMETRY;

ASYMMETRIC DIMETHYLARGININE; BIOLOGICAL SAMPLES; EXCRETION RATES; GAS CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; INTERNAL STANDARDS; QUANTITATIVE DETERMINATIONS; SYMMETRIC DIMETHYLARGININE; URINE SAMPLE;

GAS CHROMATOGRAPHY;

CREATININE; N(G),N(G) DIMETHYLARGININE;

ADULT; ARTICLE; CREATININE BLOOD LEVEL; GAS CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; URINALYSIS; URINARY EXCRETION;

EID: 79953723439     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.02.002     Document Type: Article

References (7)

1. D. Tsikas, A critical review and discussion of analytical methods in the L-arginine/nitric oxide (NO) area of basic and clinical research, Anal. Biochem. 379 (2008) 139-163.
2. D. Tsikas, J. Sandmann, A. Savva, P. Luessen, R.H. Böger, F.M. Gutzki, B. Mayer, J.C. Frölich, Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry, J. Chromatogr. B 742 (2000) 143-153. (Pubitemid 30330932)
3. D. Tsikas, B. Schubert, F-M. Gutzki, J. Sandmann, J.C. Frölich, Quantitative determination of circulating and urinary asymmetric dimethylarginine (ADMA) in human by gas chromatography-tandem mass spectrometry as methyl ester tri(N-pentafluoropropionyl) derivative, J. Chromatogr. B 798 (2003) 87-99. (Pubitemid 37421285)
4. J.T. Kielstein, S.R. Salpeter, S.M. Bode-Böger, J.P. Cooke, D. Fliser, Symmetric dimethylarginine (SDMA) as endogenous marker of renal function: a metaanalysis, Nephrol. Dial. Transplant. 21 (2006) 2446-2451. (Pubitemid 44644516)
5. J. Albsmeier, E. Schwedhelm, F. Schulze, M. Kastner, R.H. Böger, Determination of NG, NG-dimethyl-l-arginine, an endogenous NO synthase inhibitor, by gas chromatography-mass spectrometry, J. Chromatogr. B 809 (2004) 59-65. (Pubitemid 38998420)
6. J. Martens-Lobenhoffer, S.M. Bode-Böger, Chromatographic-mass spectrometric methods for the quantification of L-arginine and its methylated metabolites in biological fluids, J. Chromatogr. B 851 (2007) 30-41. (Pubitemid 46720133)
7. D. Tsikas, A proposal for comparing methods of quantitative analysis of endogenous compounds in biological systems by using the relative lower limit of quantification (rLLOQ), J. Chromatogr. B 877 (2009) 2244-2251.