The value of hyperbilirubinaemia in the diagnosis of acute appendicitis

Annals of the Royal College of Surgeons of England

Volumn 93, Issue 3, 2011, Pages 213-217

  Emmanuel, Andrew ^a,b   Murchan, Peter ^b   Wilson, Ian ^a   Balfe, Paul ^a  

^a St Lukes General Hospital Kilkenny   (Ireland)

^b South Tipperary General Hospital   (Ireland)

Author keywords

Appendicitis; Bilirubin; Diagnosis

Indexed keywords

BILIRUBIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN;

ADOLESCENT; ADULT; AGED; APPENDECTOMY; APPENDICITIS; ARTICLE; BLOOD; CHILD; FEMALE; HUMAN; HYPERBILIRUBINEMIA; LEUKOCYTE; MALE; METABOLISM; MIDDLE AGED; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; APPENDECTOMY; APPENDICITIS; BILIRUBIN; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPERBILIRUBINEMIA; LEUKOCYTES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 79953721680     PISSN: 00358843     EISSN: None     Source Type: Journal    
DOI: 10.1308/147870811X566402     Document Type: Article

References (33)

1. Hallan S, Asberg A. The accuracy of C-reactive protein in diagnosing acute appendicitis - a meta-analysis. Scand J Clin Lab Invest 1997; 57: 373-380.
2. Grönroos JM, Grönroos P. Leucocyte count and C-reactive protein in the diagnosis of acute appendicitis. Br J Surg 1999; 86: 501-504.
3. Ortega-Deballon P, Ruiz de Adana-Belbel JC, Hernández-Matías A et al. Usefulness of laboratory data in the management of right iliac fossa pain in adults. Dis Colon Rectum 2008; 51: 1,093-1,099.
4. Miller DF, Irvine RW. Jaundice in acute appendicitis. Lancet 1969; 1: 321-323.
5. Estrada JJ, Petrosyan M, Barnhart J et al. Hyperbilirubinemia in appendicitis: a new predictor of perforation. J Gastrointest Surg 2007; 11: 714-718.
6. Sand M, Bechara FG, Holland-Letz T et al. Diagnostic value of hyperbilirubinemia as a predictive factor for appendiceal perforation in acute appendicitis. Am J Surg 2009; 198: 193-198.
7. Varadhan KK, Humes DJ, Neal KR, Lobo DN. Antibiotic therapy versus appendectomy for acute appendicitis: a meta-analysis. World J Surg 2010; 34: 199-209.
8. Hanson J, Körner U, Khorram-Manesh A et al. Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients. Br J Surg 2009; 96: 473-481.
9. Eriksson S, Granström L. Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis. Br J Surg 1995; 82: 166-169.
10. Styrud J, Eriksson S, Nilsson I et al. Appendectomy versus antibiotic treatment in acute appendicitis: a prospective multicenter randomized controlled trial. World J Surg 2006; 30: 1,033-1,037.
11. Whitehead MW, Hainsworth I, Kingham JG. The causes of obvious jaundice in South West Wales: perceptions versus reality. Gut 2001; 48: 409-413.
12. Chand N, Sanyal AJ. Sepsis-induced cholestasis. Hepatology 2007; 45: 230-241.
13. Shander A. Anemia in the critically ill. Crit Care Clin 2004; 20: 159-178.
14. Roelofsen H, van der Veere CN, Ottenhoff R et al. Decreased bilirubin transport in the perfused liver of endotoxemic rats. Gastroenterology 1994; 107: 1,075-1,084.
15. Bolder U, Ton-Nu HT, Schteingart CD et al. Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion. Gastroenterology 1997; 112: 214-225.
16. Green RM, Beier D, Gollan JL. Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents. Gastroenterology 1996; 111: 193-198.
17. Whiting JF, Green RM, Rosenbluth AB, Gollan JL. Tumor necrosis factoralpha decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis. Hepatology 1995; 22: 1,273-1,278.
18. Brook I. Bacterial studies of peritoneal cavity and postoperative surgical wound drainage following perforated appendix in children. Ann Surg 1980; 192: 208-212.
19. Baron EJ, Bennion R, Thompson J et al. A microbial comparison between acute and complicated appendicitis. Clin Infect Dis 1992; 14: 227-231.
20. Agrez MV, House AK, Quinlan MF. Jaundice may herald an appendiceal abscess. Aust N Z J Surg 1986; 56: 511-513.
21. Ogilvie TA. Acholuric jaundice and appendicitis. Br J Surg 1951; 38: 529-530.
22. Dawes T, Burrows C. Abdominal pain and jaundice: appendiceal perforation an important differential. Emerg Med Australas 2007; 19: 276-278.
23. Käser SA, Fankhauser G, Willi N, Maurer CA. C-reactive protein is superior to bilirubin for anticipation of perforation in acute appendicitis. Scand J Gastroenterol 2010; 45: 885-892.
24. Dueholm S, Bagi P, Bud M. Laboratory aid in the diagnosis of acute appendicitis. A blinded, prospective trial concerning diagnostic value of leukocyte count, neutrophil differential count, and C-reactive protein. Dis Colon Rectum 1989; 32: 855-859.
25. Raman SS, Lu DS, Kadell BM et al. Accuracy of nonfocused helical CT for the diagnosis of acute appendicitis: a 5-year review. Am J Roentgenol 2002; 178: 1,319-1,325.
26. Flum DR, McClure TD, Morris A, Koepsell T. Misdiagnosis of appendicitis and the use of diagnostic imaging. J Am Coll Surg 2005; 201: 933-939.
27. Lee SL, Walsh AJ, Ho HS. Computed tomography and ultrasonography do not improve and may delay the diagnosis and treatment of acute appendicitis. Arch Surg 2001; 136: 556-562.
28. Hong JJ, Cohn SM, Ekeh AP et al. A prospective randomized study of clinical assessment versus computed tomography for the diagnosis of acute appendicitis. Surg Infect (Larchmt) 2003; 4: 231-239.
29. Pritchett CV, Levinsky NC, Ha YP et al. Management of acute appendicitis: the impact of CT scanning on the bottom line. J Am Coll Surg 2010; 210: 699-705.
30. Lin KH, Leung WS, Wang CP, Chen WK. Cost analysis of management in acute appendicitis with CT scanning under a hospital global budgeting scheme. Emerg Med J 2008; 25: 149-152.
31. Paulson EK, Kalady MF, Pappas TN. Clinical practice. Suspected appendicitis. N Engl J Med 2003; 348: 236-242.
32. Andersson RE, Hugander A, Ravn H et al. Repeated clinical and laboratory examinations in patients with an equivocal diagnosis of appendicitis. World J Surg 2000; 24: 479-485.
33. Kirby CP, Sparnon AL. Active observation of children with possible appendicitis does not increase morbidity. ANZ J Surg 2001; 71: 412-413.