Peptidomics-based discovery of an antimicrobial peptide derived from insulin-like growth factor-binding protein 5

Journal of Proteome Research

Volumn 10, Issue 4, 2011, Pages 1870-1880

  Osaki, Tsukasa ^a   Sasaki, Kazuki ^a   Minamino, Naoto ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

antimicrobial peptide; bioactive peptide; insulin like growth factor binding protein 5; mass spectrometry; Peptidomics; proteolytic processing; secretopeptidome

Indexed keywords

AMINO ACID; BETA DEFENSIN 2; CATHELICIDIN; DISULFIDE; PEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN PRECURSOR; SOMATOMEDIN BINDING PROTEIN 5;

AMIDATION; AMINO ACID BLOOD LEVEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOINFORMATICS; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; MASS SPECTROMETRY; MICROORGANISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PEPTIDOMICS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PROCESSING; RAT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; MASS SPECTROMETRY; MICE; MOLECULAR SEQUENCE DATA; PROTEOMICS; RATS; RATS, SPRAGUE-DAWLEY; SEQUENCE ALIGNMENT;

RATTUS; SUIDAE;

EID: 79953718792     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr101114a     Document Type: Article

References (34)

1. Clynen, E.; Baggerman, G.; Veelaert, D.; Cerstiaens, A.; Van der Horst, D.; Harthoorn, L.; Derua, R.; Waelkens, E.; De Loof, A.; Schoofs, L. Peptidomics of the pars intercerebralis-corpus cardiacum complex of the migratory locust, Locusta migratoria Eur. J. Biochem. 2001, 268, 1929-1939 (Pubitemid 32852934)
2. Schrader, M.; Schulz-Knappe, P. Peptidomics technologies for human body fluids Trends Biotechnol. 2001, 19, S55-60
3. Boonen, K.; Baggerman, G.; DHertog, W.; Husson, S. J.; Overbergh, L.; Mathieu, C.; Schoofs, L. Neuropeptides of the islets of Langerhans: a peptidomics study Gen. Comp. Endocrinol. 2007, 152, 231-241 (Pubitemid 46950889)
4. Sasaki, K.; Satomi, Y.; Takao, T.; Minamino, N. Snapshot peptidomics of the regulated secretory pathway Mol. Cell. Proteomics 2009, 8, 1638-1647
5. Sasaki, K.; Takahashi, N.; Satoh, M.; Yamasaki, M.; Minamino, N. A peptidomics strategy for discovering endogenous bioactive peptides J. Proteome Res. 2010, 9, 5047-5052
6. Harder, J.; Bartels, J.; Christophers, E.; Schröder, J. M. A peptide antibiotic from human skin Nature 1997, 387, 861
7. Gudmundsson, G. H.; Agerberth, B.; Odeberg, J.; Bergman, T.; Olsson, B.; Salcedo, R. The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes Eur. J. Biochem. 1996, 238, 325-332 (Pubitemid 26188246)
8. Beattie, J.; Allan, G. J.; Lochrie, J. D.; Flint, D. J. Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis Biochem. J. 2006, 395, 1-19
9. Kaku, M.; Nishiyama, T.; Yagawa, K.; Abe, M. Establishment of a carcinoembryonic antigen-producing cell line from human pancreatic carcinoma Gann 1980, 71, 596-601 (Pubitemid 10030514)
10. Andersson, E.; Rydengård, V.; Sonesson, A.; Mörgelin, M.; Björck, L.; Schmidtchen, A. Antimicrobial activities of heparin-binding peptides Eur. J. Biochem. 2004, 271, 1219-1226 (Pubitemid 38373054)
11. Saito, T.; Kawabata, S.; Sigenaga, T.; Takayenoki, Y.; Cho, J.; Nakajima, H.; Hirata, M.; Iwanaga, S. A novel big defensin identified in horseshoe crab hemocytes: isolation, amino acid sequence, and antibacterial activity J. Biochem. 1995, 117, 1131-1137
12. Osaki, T.; Omotezako, M.; Nagayama, R.; Hirata, M.; Iwanaga, S.; Kasahara, J.; Hattori, J.; Ito, I.; Sugiyama, H.; Kawabata, S. Horseshoe crab hemocyte-derived antimicrobial polypeptides, tachystatins, with sequence similarity to spider neurotoxins J. Biol. Chem. 1999, 274, 26172-26178
13. Fisher, E. R.; Paulson, J. D. A new in vitro cell line established from human large cell variant of oat cell lung cancer Cancer Res. 1978, 38, 3830-38359
14. Katafuchi, T.; Kikumoto, K.; Hamano, K.; Kangawa, K.; Matsuo, H.; Minamino, N. Calcitonin receptor-stimulating peptide, a new member of the calcitonin gene-related peptide family. Its isolation from porcine brain, structure, tissue distribution, and biological activity J. Biol. Chem. 2003, 278, 12046-12054 (Pubitemid 36800181)
15. Yamaguchi, H.; Sasaki, K.; Satomi, Y.; Shimbara, T.; Kageyama, H.; Mondal, M. S.; Toshinai, K.; Date, Y.; González, L. J.; Shioda, S.; Takao, T.; Nakazato, M.; Minamino, N. Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -2 J. Biol. Chem. 2007, 282, 26354-26360 (Pubitemid 47443772)
16. Shoji, H.; Minamino, N.; Kangawa, K.; Matsuo, H. Endotoxin markedly elevates plasma concentration and gene transcription of adrenomedullin in rat Biochem. Biophys. Res. Commun. 1995, 215, 531-537
17. Osaki, T.; Okino, N.; Tokunaga, F.; Iwanaga, S.; Kawabata, S. Proline-rich cell surface antigens of horseshoe crab hemocytes are substrates for protein cross-linking with a clotting protein coagulin J. Biol. Chem. 2002, 277, 40084-40090 (Pubitemid 35190998)
18. Brunner, Y.; Coute, Y.; Lezzi, M.; Foti, M.; Fukuda, M.; Hochstrasser, D. F.; Wollheim, C. B.; Sanchez, J.-C. Proteomics analysis of insulin secretory granules Mol. Cell. Proteomics 2007, 6, 1007-1017 (Pubitemid 47019402)
19. Zhou, A.; Webb, G.; Zhu, X.; Steiner, D. F. Proteolytic processing in the secretory pathway J. Biol. Chem. 1999, 274, 20745-20748
20. Fricker, L. D. Neuropeptide-processing enzymes: applications for drug discovery AAPS J. 2005, 7, E449-455
21. Travis, S. M.; Anderson, N. N.; Forsyth, W. R.; Espiritu, C.; Conway, B. D.; Greenberg, E. P.; McCray, P. B., Jr; Lehrer, R. I.; Welsh, M. J.; Tack, B. F. Bactericidal activity of mammalian cathelicidin-derived peptides Infect. Immun. 2000, 68, 2748-2755 (Pubitemid 30253851)
22. Bals, R.; Wang, X.; Wu, Z.; Freeman, T.; Bafna, V.; Zasloff, M.; Wilson, J. M. Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung J. Clin. Invest. 1998, 102, 874-880 (Pubitemid 28419232)
23. Bauer, F.; Schweimer, K.; Klüver, E.; Conejo-Garcia, J. R.; Forssmann, W. G.; Rösch, P.; Adermann, K.; Sticht, H. Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity Protein Sci. 2001, 10, 2470-2479 (Pubitemid 33091570)
24. Suetake, T.; Aizawa, T.; Koganesawa, N.; Osaki, T.; Kobashigawa, Y.; Demura, M.; Kawabata, S.; Kawano, K.; Tsuda, S.; Nitta, K. Production and characterization of recombinant tachycitin, the Cys-rich chitin-binding protein Protein Eng. 2002, 15, 763-769 (Pubitemid 35470433)
25. Dos Santos Cabrera, M. P.; Arcisio-Miranda, M.; Broggio Costa, S. T.; Konno, K.; Ruggiero, J. R.; Procopio, J.; Ruggiero Neto, J. Study of the mechanism of action of anoplin, a helical antimicrobial decapeptide with ion channel-like activity, and the role of the amidated C-terminus J. Pept. Sci. 2008, 14, 661-669 (Pubitemid 351982710)
26. Tenover, F.; Swenson, J. M.; OHara, C. M.; Stocker, S. A. Ability of commercial and reference antimicrobial and reference antimicrobial susceptibility testing methods to detect vancomycin resistance in enterococci J. Clin. Microbiol. 1995, 33, 1524-1527
27. Yajko, D. M.; Madej, J. J.; Lancaster, M. V.; Sanders, C. A.; Cawthon, V. L.; Gee, B.; Babst, A.; Hadley, W. K. Colorimetric method for determining MICs of antimicrobial agents for Mycrobacterium tuberculosis J. Clin. Microbiol. 1995, 33, 2324-2327
28. DeForge, L. E.; Billeci, K. L.; Kramer, S. M. Effect of IFN-α on the killing of S. aureus in human whole blood. Assessment of bacterial viability by CFU determination and by a new method using alamarBlue J. Immunol. Methods 2000, 245, 79-89
29. Firth, S. M.; Baxter, R. C. Cellular actions of the insulin-like growth factor binding proteins Endocr. Rev. 2002, 23, 824-854 (Pubitemid 35454590)
30. Zasloff, M. Antimicrobial peptides of multicellular organisms Nature 2002, 415, 389-395 (Pubitemid 34100944)
31. Tateishi, K.; Arakawa, F.; Misumi, Y.; Treston, A. M.; Vos, M.; Matsuoka, Y. Isolation and functional expression of human pancreatic peptidylglycine alpha-amidating monooxygenase Biochem. Biophys. Res. Commun. 1994, 205, 282-290 (Pubitemid 24381623)
32. Minamino, N.; Kangawa, K.; Matsuo, H. Neuromedin C: a bombesin-like peptide identified in porcine spinal cord Biochem. Biophys. Res. Commun. 1984, 119, 14-20 (Pubitemid 14168166)
33. Zhang, X.; Pan, H.; Peng, B.; Steiner, D. F.; Pintart, J. E.; Fricker, L. D. Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis J. Neurochem. 2010, 112, 1168-1179
34. Kalus, W.; Zweckstetter, M.; Renner, C.; Sanchez, Y.; Georgescu, J.; Grol, M.; Demuth, D.; Schumacher, R.; Dony, C.; Lang, K.; Holak, T. A. Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions EMBO J. 1998, 17, 6558-6572 (Pubitemid 28521791)