The fate of chrysotile-induced multipolar mitosis and aneuploid population in cultured lung cancer cells

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  de Araujo Cortez, Beatriz ^a   Quassollo, Gonzalo ^b   Caceres, Alfredo ^b   Machado Santelli, Glaucia Maria ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; CHRYSOTILE;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL COUNT; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL FATE; CELL FUSION; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINESIS; DAUGHTER CELL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; METAPHASE; MITOSIS; MULTIPOLAR MITOSIS; NONHUMAN; TELOPHASE;

ANEUPLOIDY; ANIMALS; ASBESTOS, SERPENTINE; CELL LINE, TUMOR; CENTROSOME; CERCOPITHECUS AETHIOPS; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG NEOPLASMS; MITOSIS; TIME FACTORS; VERO CELLS;

EID: 79953716275     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018600     Document Type: Article

References (38)

1. Mossman BT, Bignon J, Corn M, Seaton A, Gee JB, (1990) Asbestos: scientific developments and implications for public policy. Science 247: 294-301.
2. Mossman BT, Churg A, (1998) Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med 157: 1666-1680.
3. Bernstein D, Rogers R, Smith P, (2005) The biopersistence of Canadian chrysotile asbestos following inhalation: final results through 1 year after cessation of exposure. Inhal Toxicol 17: 1-14.
4. Suzuki K, Hei TK, (1996) Induction of heme oxygenase in mammalian cells by mineral fibers: distinctive effect of reactive oxygen species. Carcinogenesis 17: 661-667.
5. Dopp E, Yadav S, Ansari FA, Bhattacharya K, von Recklinghausen U, et al. (2005) ROS-mediated genotoxicity of asbestos-cement in mammalian lung cells in vitro. Part Fibre Toxicol 2: 9.
6. Xu A, Wu LJ, Santella RM, Hei TK, (1999) Role of oxyradicals in mutagenicity and DNA damage induced by crocidolite asbestos in mammalian cells. Cancer Res 59: 5922-5926.
7. Okayasu R, Takahashi S, Yamada S, Hei TK, Ullrich RL, (1999) Asbestos and DNA double strand breaks. Cancer Res 59: 298-300.
8. Burmeister B, Schwerdtle T, Poser I, Hoffmann E, Hartwig A, et al. (2004) Effects of asbestos on initiation of DNA damage, induction of DNA-strand breaks, P53-expression and apoptosis in primary, SV40-transformed and malignant human mesothelial cells. Mutat Res 558: 81-92.
9. Xu A, Smilenov LB, He P, Masumura K, Nohmi T, et al. (2007) New insight into intrachromosomal deletions induced by chrysotile in the gpt delta transgenic mutation assay. Environ Health Perspect 115: 87-92.
10. Levresse V, Renier A, Fleury-Feith J, Levy F, Moritz S, et al. (1997) Analysis of cell cycle disruptions in cultures of rat pleural mesothelial cells exposed to asbestos fibers. Am J Respir Cell Mol Biol 17: 660-671.
11. Dopp E, Schuler M, Schiffmann D, Eastmond DA, (1997) Induction of micronuclei, hyperdiploidy and chromosomal breakage affecting the centric/pericentric regions of chromosomes 1 and 9 in human amniotic fluid cells after treatment with asbestos and ceramic fibers. Mutat Res 377: 77-87.
12. Levresse V, Renier A, Levy F, Broaddus VC, Jaurand M, (2000) DNA breakage in asbestos-treated normal and transformed (TSV40) rat pleural mesothelial cells. Mutagenesis 15: 239-244.
13. Cortez BA, Machado-Santelli GM, (2008) Chrysotile effects on human lung cell carcinoma in culture: 3-D reconstruction and DNA quantification by image analysis. BMC Cancer 8: 181.
14. Jensen CG, Watson M, (1999) Inhibition of cytokinesis by asbestos and synthetic fibres. Cell Biol Int 23: 829-840.
15. Sargent LM, Reynolds SH, Castranova V, (2010) Potential pulmonary effects of engineered carbon nanotubes: in vitro genotoxic effects. Nanotoxicology 4: 396-408.
16. Machado-Santelli GM, Mori L, Pereira CA, (1994) Prediction of relapse in patients with breast cancer by DNA cytometry. Anal Cell Pathol 7: 321-334.
17. Pathak S, Multani AS, (2006) Aneuploidy, stem cells and cancer. EXS pp. 49-64.
18. Duesberg P, Li R, Fabarius A, Hehlmann R, (2006) Aneuploidy and cancer: from correlation to causation. Contrib Microbiol 13: 16-44.
19. Fukasawa K, (2005) Centrosome amplification, chromosome instability and cancer development. Cancer Lett 230: 6-19.
20. Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, et al. (1999) Creation of human tumour cells with defined genetic elements. Nature 400: 464-468.
21. Li R, Sonik A, Stindl R, Rasnick D, Duesberg P, (2000) Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy. Proc Natl Acad Sci U S A 97: 3236-3241.
22. Hede K, (2005) Which came first? Studies clarify role of aneuploidy in cancer. J Natl Cancer Inst 97: 87-89.
23. Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW, (2007) Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell 11: 25-36.
24. Lengauer C, Kinzler KW, Vogelstein B, (1997) Genetic instability in colorectal cancers. Nature 386: 623-627.
25. Bonaldo Mde F, Pestano CB, Ribeiro MC, Machado-Santelli GM, Mori L, et al. (1991) Comparative characterization of a human large cell lung carcinoma cell line and the xenograft derived cell line. Cell Biol Int Rep 15: 229-241.
26. Cassiola F, Rogers RA, Kiyohara PK, Joekes I, (2005) Yeast cells long-term interaction with asbestos fibers. Colloids Surf B Biointerfaces 41: 277-283.
27. Bourke E, Dodson H, Merdes A, Cuffe L, Zachos G, et al. (2007) DNA damage induces Chk1-dependent centrosome amplification. EMBO Rep 8: 603-609.
28. Ame JC, Fouquerel E, Gauthier LR, Biard D, Boussin FD, et al. (2009) Radiation-induced mitotic catastrophe in PARG-deficient cells. J Cell Sci 122: 1990-2002.
29. Borojerdi JP, Ming J, Cooch C, Ward Y, Semino-Mora C, et al. (2009) Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells. Mutat Res 665: 67-74.
30. Kuriyama R, Terada Y, Lee KS, Wang CL, (2007) Centrosome replication in hydroxyurea-arrested CHO cells expressing GFP-tagged centrin2. J Cell Sci 120: 2444-2453.
31. Kawamura K, Izumi H, Ma Z, Ikeda R, Moriyama M, et al. (2004) Induction of centrosome amplification and chromosome instability in human bladder cancer cells by p53 mutation and cyclin E overexpression. Cancer Res 64: 4800-4809.
32. Weaver BA, Cleveland DW, (2005) Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death. Cancer Cell 8: 7-12.
33. Liu ST, van Deursen JM, Yen TJ, (2003) The role of mitotic checkpoint in maintaining genomic stability. Curr Top Dev Biol 58: 27-51.
34. Hanks S, Coleman K, Reid S, Plaja A, Firth H, et al. (2004) Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nature Genetics 36: 1159-1161.
35. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JKV, et al. (1998) Mutations of mitotic checkpoint genes in human cancers. Nature 392: 300-303.
36. Brody AR, Liu JY, Brass D, Corti M, (1997) Analyzing the genes and peptide growth factors expressed in lung cells in vivo consequent to asbestos exposure and in vitro. Environ Health Perspect 105 (Suppl 5): 1165-1171.
37. Brody AR, McGavran PD, Overby LH, (1989) Brief inhalation of chrysotile asbestos induces rapid proliferation of bronchiolar-alveolar epithelial and interstitial cells. IARC Sci Publ pp. 93-99.
38. Quinlan TR, BeruBe KA, Marsh JP, Janssen YM, Taishi P, et al. (1995) Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos. Am J Pathol 147: 728-739.