Angiotensin converting enzyme insertion/deletion gene polymorphisms in leukemic hematopoiesis;Lösemik hematopoezde kemik i̇liǧi anjiotensin II tip I reseptör gen ve anjiotensin Dönüştürücü enzim (ACE) İnsersiyon/delesyon (I/D) gen polimorfizmleri

UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi

Volumn 21, Issue 1, 2011, Pages 1-9

  Akalin, Ibrahim ^a   Koca, Ebru ^a   Karabulut, Halil G ^a   Haznedaroglu, Ibrahim C ^a   Cetiner, Deniz ^a   Hayran, Mutlu ^a   Onal, Ibrahim K ^b   Ozcebe, Osman I ^a   Tukun, Ajlan ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

ACE I D gene polymorphism; Angiotensin converting enzyme; Angiotensin II; Leukemic hematopoiesis; Local renin angiotensin system

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ACUTE LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE DELETION; GENE INSERTION; GENOTYPE; HEMATOPOIESIS; HUMAN; MALE; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME;

EID: 79953693916     PISSN: 1306133X     EISSN: None     Source Type: Journal    
DOI: 10.4999/uhod.09164     Document Type: Article

References (47)

1. Montgomery H, Humphries SE, Leung PS. Renin-an- giotensin systems: the new frontier. Int J Biochem Cell Biol 35: 758, 2003.
2. Haznedaroglu IC, Buyukasik Y. Current evidence for the existence of a local renin-angiotensin system affec- ting physiological and pathological haemopoiesis in the bone marrow. Br J Haematol 99: 471, 1997.
3. Haznedaroglu IC, Tuncer S, Gursoy M. A local renin- angiotensin system in the bone marrow. Med Hypot- heses 46: 507-510, 1996.
4. Rodgers KE, Xiong S, Steer R, diZerega GS. Effect of angiotensin II on hematopoietic progenitor cell prolife- ration. Stem Cells 18: 287-294, 2000.
5. Strawn WB, Richmond RS, Ann Tallant E, et al. Renin- angiotensin system expression in rat bone marrow ha- ematopoietic and stromal cells. Br J Haematol 126: 120-126, 2004.
6. Abali H, Haznedaroglu IC, Goker H, et al. Circulating and local bone marrow renin-angiotensin system in le- ukemic hematopoiesis: preliminary evidences. Hema- tology 7: 75-82, 2002.
7. Goker H, Haznedaroglu IC, Beyazit Y, et al. Local um- bilical cord blood renin-angiotensin system. Ann He- matol 84: 277-281, 2005.
8. Pinto RP, Wang KK, Khoury H, et al. Aberrant Expres- sion of Angiotensin in acute Myeloid Leukemia. Blood 102: 2124A. 2003.
9. Aksu S, Beyazit Y, Haznedaroglu IC, et al. Over-exp- ression of angiotensin-converting enzyme (CD 143) on leukemic blasts as a clue for the activated local bone marrow RAS in AML. Leuk Lymphoma 47: 891-896, 2006.
10. Beyazit Y, Aksu S, Haznedaroglu IC, et al. Overexpres- sion of the local bone marrow renin-angiotensin sys- tem in acute myeloid leukemia. J Natl Med Assoc 99: 57-63, 2007
11. Soubrier F, Alhenc-Gelas F, Hubert C, et al. Two puta-tive active centers in human angiotensin I-converting enzyme revealed by molecular cloning. Proc Natl Acad Sci USA 85: 9386-9390, 1988.
12. Hubert C, Houot AM, Corvol P, Soubrier F. Structure of the angiotensin I-converting enzyme gene. Two al- ternate promoters correspond to evolutionary steps of a duplicated gene. J Biol Chem 266: 15377-15383, 1991.
13. Coates D. The angiotensin converting enzyme (ACE). Int J Biochem Cell Biol 35: 769-773, 2003.
14. Rigat B, Hubert C, Alhenc-Gelas F, et al. An inserti- on/deletion polymorphism in the angiotensin I-conver- ting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86: 1343-1346, 1990.
15. Cambien F, Poirier O, Lecerf L, et al. Deletion poly- morphism in the gene for angiotensin-converting enzy- me is a potent risk factor for myocardial infarction. Na- ture 359: 641-644, 1992.
16. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detecti- on of the insertion/deletion polymorphism of the hu- man angiotensin converting enzyme gene (DCP1) (di- peptidyl carboxypeptidase 1). Nucleic Acids Res 20: 1433, 1992.
17. Shanmugam V, Sell KW, Saha BK. Mistyping ACE he- terozygotes. PCR Methods Appl 3: 120-121, 1993.
18. Tiret L, Rigat B, Visvikis S, et al. Evidence, from com- bined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 51: 197-205, 1992.
19. Nussbaum LR, McInnes RR, Willard HF. Organization of the human genome. In Thompson & Thompson Ge- netics in Medicine, Sixth Edition ed. Philadelphia, Sa- unders, 2004, 31.
20. Suehiro T, Morita T, Inoue M, et al. Increased amount of the angiotensin-converting enzyme (ACE) mRNA originating from the ACE allele with deletion. Hum Ge- net 115: 91-96, 2004.
21. Akar N, Aras O, Omurlu K, Cin S. Deletion polymorp- hism at the angiotensin-converting enzyme gene in Turkish patients with coronary artery disease. Scand J Clin Lab Invest 58: 491-495, 1998.
22. Arbustini E, Grasso M, Fasani R, et al. Angiotensin converting enzyme gene deletion allele is indepen- dently and strongly associated with coronary athe- rosclerosis and myocardial infarction. Br Heart J 74: 584-591, 1995.
23. Amant C, Bauters C, Bodart JC, et al. D allele of the angiotensin I-converting enzyme is a major risk factor for restenosis after coronary stenting. Circulation 96: 56-60, 1997.
24. Bohn M, Berge KE, Bakken A, et al. Insertion/deletion (I/D) polymorphism at the locus for angiotensin I-con- verting enzyme and parental history of myocardial in- farction. Clin Genet 44: 298-301, 1993.
25. Ueda S, Elliott HL, Morton JJ, Connell JM. Enhanced pressor response to angiotensin I in normotensive men with the deletion genotype (DD) for angiotensin- converting enzyme. Hypertension 25:1266-1269, 1995.
26. Danser AH, Derkx FH, Hense HW, et al. Angiotensino- gen (M235T) and angiotensin-converting enzyme (I/D) polymorphisms in association with plasma renin and prorenin levels. J Hypertens 16: 1879-1883, 1998.
27. Chadwick IG, O'Toole L, Morice AH, et al. Pressor and hormonal responses to angiotensin I infusion in healthy subjects of different angiotensin-converting enzyme genotypes. J Cardiovasc Pharmacol 29:485-489, 1997.
28. Danser AH, Deinum J, Osterop AP, et al. Angiotensin I to angiotensin II conversion in the human forearm and leg. Effect of the angiotensin converting enzyme gene insertion/deletion polymorphism. J Hypertens 17: 1867-1872, 1999.
29. van Dijk MA, Kroon I, Kamper AM, et al.The angioten- sin-converting enzyme gene polymorphism and res- ponses to angiotensins and bradykinin in the human forearm. J Cardiovasc Pharmacol 35: 484-490, 2000.
30. Danser AH. Local renin-angiotensin systems: the unanswered questions. Int J Biochem Cell Biol 35: 759-768, 2003.
31. Gonzalez-Zuloeta Ladd AM, Vasquez AA, Sayed-Ta- batabaei FA, et al. Angiotensin-converting enzyme ge- ne insertion/deletion polymorphism and breast cancer risk. Cancer Epidemiol Biomarkers Prev 14:2143-2146, 2005.
32. Rocken C, Rohl FW, Diebler E, et al. The angiotensin II/angiotensin II receptor system correlates with nodal spread in intestinal type gastric cancer. Cancer Epi- demiol Biomarkers Prev 16: 1206-1212, 2007.
33. Yaren A, Turgut S, Kursunluoglu R, et al. Inser- tion/Deletion polymorphism of the Angiotensin I-con- verting enzyme gene in patients with breast cancer and effects on prognostic factors. J Investig Med 55: 255-261, 2007.
34. Yigit B, Bozkurt N, Narter F, et al. Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. Anticancer Res 27: 933-936, 2007.
35. Freitas-Silva M, Pereira D, Coelho C, et al. Angiotensin I-converting enzyme gene insertion/deletion polymorp- hism and endometrial human cancer in normotensive and hypertensive women. Cancer Genet Cytogenet 155: 42-46, 2004.
36. Vairaktaris E, Yapijakis C, Tsigris C, et al. Association of angiotensin-converting enzyme gene inser- tion/deletion polymorphism with increased risk for oral cancer. Acta Oncol 46: 1097-1102, 2007.
37. Haiman CA, Henderson SO, Bretsky P, et al. Genetic variation in angiotensin I-converting enzyme (ACE) and breast cancer risk: the multiethnic cohort. Cancer Res 63: 6984-6987, 2003
38. Nussbaum LR, McInnes RR, Willard HF. Genetic vari- ation in populations. In Thompson & Thompson Genetics in Medicine, 6th ed. Philadelphia, Saunders, 2004, 95-109.
39. Koca E, Haznedaroglu IC, Acar K, et al. Renin-an- giotensin system expression in the K562 human eryth- roleukaemic cell line. J Renin Angiotensin Aldosterone Syst 8: 145-147, 2007.
40. Campbell DJ, Habener JF. Angiotensinogen gene is expressed and differentially regulated in multiple tis- sues of the rat. J Clin Invest 78: 31-39, 1986.
41. Yin G, Yan C, Berk BC. Angiotensin II signaling path- ways mediated by tyrosine kinases. Int J Biochem Cell Biol 35: 780-783, 2003.
42. Kumar V, Abbas AK, Fausto N. Growth factors. In Robbins and Cotran Pathologic Basis of Disease, 7th ed. Philadelphia, Elsevier Saunders, 2005, p. 95-118.
43. Suzuki Y, Ruiz-Ortega M, Lorenzo O, et al. Inflam- mation and angiotensin II. Int J Biochem Cell Biol 35: 881-900, 2003.
44. Marrero MB, Schieffer B, Paxton WG, et al. Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor. Nature 375: 247-250, 1995.
45. Haznedaroglu IC, Arici M, Buyukasik Y. A unifying hypothesis for the renin-angiotensin system and hematopoiesis: sticking the pieces together with the JAK-STAT pathway. Med Hypotheses 54:80-83, 2000.
46. Haznedaroglu IC, Ozturk MA. Towards the understan- ding of the local hematopoietic bone marrow renin-an- giotensin system. Int J Biochem Cell Biol 35: 867-880, 2003.
47. Leung PS, Fung ML, Tam MS. Renin-angiotensin sys- tem in the carotid body. Int J Biochem Cell Biol 35: 847-854, 2003.