High prevalence of prolonged qt interval duration in male patients with Cushing's disease

Experimental and Clinical Endocrinology and Diabetes

Volumn 119, Issue 4, 2011, Pages 221-224

  Pecori Giraldi, F ^a,b   Toja, P M ^a   Michailidis, G ^b   Metinidou, A ^b   De Martin, M ^b   Scacchi, M ^a,b   Stramba Badiale, M ^b   Cavagnini, F ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

cardiac arrhythmia; Cushing's syndrome; hypogonadism; QT interval

Indexed keywords

TESTOSTERONE;

ADOLESCENT; ADULT; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CUSHING DISEASE; ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; HEART VENTRICLE ARRHYTHMIA; HUMAN; HYPOKALEMIA; MAJOR CLINICAL STUDY; MALE; PREVALENCE; PRIORITY JOURNAL; QT PROLONGATION; SEX DIFFERENCE; TORSADE DES POINTES;

ADOLESCENT; ADULT; AGE FACTORS; ARRHYTHMIAS, CARDIAC; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; PITUITARY ACTH HYPERSECRETION; PREVALENCE; RISK FACTORS; SEX CHARACTERISTICS;

EID: 79953688969     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0031-1271628     Document Type: Article

References (25)

1. The University of Arizona center for Education and Resarch on Therapeutics. Drugs that prolong the QT interval and/or induce torsade de pointes ventricular arrhythmia (updated 8/9/2010). Available from www.azcert.org/medical-pros/drug-lists/drug-lists.htm
2. Abi-Gerges N, Philp K, Pollard C et al,. Sex differences in ventricular repolarization: from cardiac electrophysiology to torsades de pointes. Fundam Clin Pharmacol 2004 18 139-151 (Pubitemid 38491286)
3. Al-Khatib SM, LaPointe NM, Kramer JM et al,. What clinicians should know about the QT interval. JAMA 2003 289 2120-2127 (Pubitemid 37430214)
4. Casale PN, Devereux RB, Alonso DR et al,. Improved sex-specific criteria of left ventricular hypertrophy for clinical and computer interpretation of electrocardiograms: validation with autopsy findings. Circulation 1987 75 565-572 (Pubitemid 17026046)
5. Fazio S, Biondi B, Lupoli G et al,. Evaluation, by noninvasive methods, of the effects of acute loss of thyroid hormones on the heart. Angiology 1992 43 287-293
6. Fraley MA, Birchem JA, Senkottaiyan N et al,. Obesity and the electrocardiogram. Obes Res 2005 6 275-281 (Pubitemid 41578598)
7. Invitti C, Pecori Giraldi F, De Martin M. et al the Study Group of the Italian Society of Endocrinology on the Pathophysiology of the Hypothalamic-Pituitary-Adrenal Axis Diagnosis and management of Cushing's syndrome: results of an Italian multicentre study. J Clin Endocrinol Metab 1999 84 440-448 (Pubitemid 29075666)
8. James AF, Choisy SCM, Hancox JC. Recent advances in understanding sex differences in cardiac repolarization. Prog Biophys Mol Biol 2007 94 265-319 (Pubitemid 46766581)
9. Mancia G, De Backer G, Dominiczak A et al,. 2007 Guidelines for the management of arterial hypertension. Eur Heart J 2007 28 1462-1536 (Pubitemid 47351115)
10. Matsumura K, Fujii K, Kansui Y et al,. Prolongation of the QT interval in primary aldosteronism. Clin Exp Pharmacol Physiol 2005 32 66-69 (Pubitemid 40320552)
11. Muiesan ML, Lupia M, Salvetti M et al,. Left ventricular structural and functional characteristics in Cushing's syndrome. J Am Coll Cardiol 2003 41 2275-2279 (Pubitemid 36724279)
12. Oikarinen L, Nieminen MS, Viitasalo M et al,. Relation of QT interval and QT dispersion to echocardigraphic left ventricular hypertrophy and geometric pattern in hypertensive patients. The LIFE study. J Hypertension 2001 19 1883-1891 (Pubitemid 32924957)
13. Pecori Giraldi F, Andrioli M, De Marinis L et al,. Significant GH deficiency after long-term cure by surgery in adult patients with Cushing's disease. Eur J Endocrinol 2007 156 235-241
14. Pecori Giraldi F, Moro M, Cavagnini F, the Study Group of the Italian Society of Endocrinology on the Pathophysiology of the Hypothalamic-Pituitary- Adrenal Axis. Gender-related differences in the presentation and course of Cushing's disease. J Clin Endocrinol Metab 2003 88 1554-1558 (Pubitemid 36623369)
15. Pecori Giraldi F, Toja PM, Filippini B et al,. Increased prevalence of prolonged QT interval in males with primary or secondary hypogonadism. A pilot study. Int J Androl 2010 33 e132-e138
16. Pham TV, Rosen MR. Sex, hormones, and repolarization. Cardiovasc Res 2002 53 740-751 (Pubitemid 34175265)
17. Rautaharju PM, Zhou SH, Wong S et al,. Sex differences in the evolution of the electrocardiographic QT interval with age. Can J Cardiol 1992 8 690-695
18. Roden DM. Drug-induced prolongation of the QT interval. N Engl J Med 2004 350 1013-1022 (Pubitemid 38269278)
19. Schwartz PJ, Moss AJ, Vincent GM et al,. Diagnostic criteria for the long QT syndrome. Circulation 1993 88 782-784
20. Ryzhikov VD. ECG changes in the active form of Itsenko-Cushing disease and in a state of clinical remission. Zdravookhr Kirg 1978 6 22-26
21. Savel'ev AA, Stepanov MA. On rhythm disorders in Itsenko-Cushing syndrome. Ter Arkh 1962 34 124-129
22. Scott BD, Friday KJ. Cushing's syndrome presenting as sudden death. Am Heart J 1988 115 487-488 (Pubitemid 18043304)
23. Stramba-Badiale M, Spagnolo D, Bosi G et al,. Are gender differences in QTc present at birth? Am J Cardiol 1995 75 1277-1278
24. Sugihara N, Shimizu M, Kita Y et al,. Cardiac characteristics and postoperative courses in Cushing's syndrome. Am J Cardiol 1992 69 1475-1480
25. Tsuda K, Saikawa T, Yonemochi H et al,. Electrocardiographic abnormalities in patients with Cushing's syndrome. Jpn Heart J 1995 36 333-339