메뉴 건너뛰기




Volumn , Issue 12, 2011, Pages 2230-2234

Concise route to (-)- and (+)-aphanorphine

Author keywords

Aminoallylation; 2 Methylpropane 2 sulfinamide; Aphanorphine; Cyclization; Indium; Natural products

Indexed keywords


EID: 79953686260     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.201100091     Document Type: Article
Times cited : (38)

References (32)
  • 3
    • 14644392139 scopus 로고    scopus 로고
    • For a recent review, see
    • For a recent review, see:, J. Zezula, T. Hudlicky, Synlett 2005, 388-405.
    • (2005) Synlett , pp. 388-405
    • Zezula, J.1    Hudlicky, T.2
  • 5
    • 79953679478 scopus 로고    scopus 로고
    • For selected recent syntheses of (-)-aphanorphine making use of the chiral pool, see
    • For selected recent syntheses of (-)-aphanorphine making use of the chiral pool, see
  • 12
    • 79953697315 scopus 로고    scopus 로고
    • For selected recent formal syntheses of (-)-aphanorphine by using an external chiral source, see
    • For selected recent formal syntheses of (-)-aphanorphine by using an external chiral source, see
  • 16
    • 79953674710 scopus 로고    scopus 로고
    • For recent reviews on the asymmetric synthesis of amines via N-(tert-butylsulfinyl)imines, see
    • For recent reviews on the asymmetric synthesis of amines via N-(tert-butylsulfinyl)imines, see
  • 25
    • 78650486772 scopus 로고    scopus 로고
    • To the best of our knowledge, there is only one formal synthesis reported for (-)-aphanorphine that relies on (R)-2-methylpropane-2-sulfinamide:,; Angew. Chem. Int. Ed. 2007, 46, 5377-5380
    • To the best of our knowledge, there is only one formal synthesis reported for (-)-aphanorphine that relies on (R)-2-methylpropane-2-sulfinamide:, R. S. Grainger, E. J. Welsh, Angew. Chem. 2007, 119, 5473
    • (2007) Angew. Chem. , vol.119 , pp. 5473
    • Grainger, R.S.1    Welsh, E.J.2
  • 30
    • 79953689829 scopus 로고    scopus 로고
    • 2OH. After careful usual workup, the aldehyde was distilled under vacuum and used immediately without further purification
    • 2OH. After careful usual workup, the aldehyde was distilled under vacuum and used immediately without further purification.
  • 32
    • 79953703929 scopus 로고    scopus 로고
    • After some experimentation, we realized that similar results were obtained by performing the cyclization with purified or crude epoxides 7. We describe in this procedure the results with crude epoxides 7
    • After some experimentation, we realized that similar results were obtained by performing the cyclization with purified or crude epoxides 7. We describe in this procedure the results with crude epoxides 7.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.