Proteomic analysis of pancreatic ductal adenocarcinoma cells reveals metabolic alterations

Journal of Proteome Research

Volumn 10, Issue 4, 2011, Pages 1944-1952

  Zhou, Weidong ^a   Capello, Michela ^b,c   Fredolini, Claudia ^a,b,c   Piemonti, Lorenzo ^d   Liotta, Lance A ^a   Novelli, Francesco ^b,c   Petricoin, Emanuel F ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b MOLINETTE HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

LTQ Orbitrap; mass spectrometry; metabolism; pancreatic ductal adenocarcinoma; proteomics; Warburg effect

Indexed keywords

24 DEHYDROCHOLESTEROL REDUCTASE PRECURSOR; 5 AMINOIMIDAZOLE 4 CARBOXAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE; 6 PHOSPHOFRUCTOKINASE; ACETYL COENZYME A ACETYLTRANSFERASE 2; ACYL COENZYME A THIOESTERASE 7; ADENOSINE TRIPHOSPHATE CITRATE LYASE; ADENYLATE KINASE 2 ISOFORM B; ADENYLOSUCCINATE LYASE ISOFORM A; ADENYLOSUCCINATE SYNTHASE; BRAIN GLYCOGEN PHOSPHORYLASE; CARBAMOYLPHOSPHATE SYNTHETASE 2; CITRATE SYNTHASE; CYTOCHROME B5 OUTER MITOCHONDRIAL MEMBRANE PRECURSOR; DEOXYURIDINE TRIPHOSPHATASE ISOFORM 1 PRECURSOR; DIHYDROPYRIMIDINASE LIKE 3; ENZYME; FATTY ACID SYNTHASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GUANINE MONOPHOSPHATE SYNTHETASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE 1; INOSINE MONOPHOSPHATE DEHYDROGENASE 2; L LACTATE DEHYDROGENASE B; LACTATE DEHYDROGENASE; PHOSPHOGLUCONATE DEHYDROGENASE; PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ISOFORM 2; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PYRUVATE KINASE; TRANSKETOLASE; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; METABOLISM; PANCREAS ADENOCARCINOMA; PANCREAS DUCT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS;

CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; HUMANS; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PROTEOME; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL;

EID: 79953684321     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr101179t     Document Type: Article

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