Putting evidence into practice: Evidence-based interventions for hot flashes resulting from cancer therapies

Clinical Journal of Oncology Nursing

Volumn 15, Issue 2, 2011, Pages 149-157

  Kaplan, Marcelle ^a   Mahon, Suzanne ^b   Cope, Diane ^c   Keating, Elizabeth ^d   Hill, Stacey ^b   Jacobson, Marcie ^e  

^a St Louis University ^*

^b Florida Cancer Specialists   (United States)

^c Memorial Health   (United States)

^d Tennessee Valley Gynecologic Oncology   (United States)

^e Florida Cancer Specialists and Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS;

ARTICLE; BREAST TUMOR; CHEMICALLY INDUCED DISORDER; EVIDENCE BASED MEDICINE; FEMALE; HOT FLUSH; HUMAN; MALE; PLACEBO EFFECT; PROSTATE TUMOR;

ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; EVIDENCE-BASED MEDICINE; FEMALE; HOT FLASHES; HUMANS; MALE; PLACEBO EFFECT; PROSTATIC NEOPLASMS;

EID: 79953652970     PISSN: 10921095     EISSN: 1538067X     Source Type: Journal    
DOI: 10.1188/11.CJON.149-157     Document Type: Article

References (72)

1. Agarwal, P.K., & Oefelein, M.G. (2005). Testosterone replacement therapy after primary treatment for prostate cancer. Journal of Urology, 173, 533-536. doi: 10.1097/01.ju.0000143942.55896.64
2. Altekruse, S.F., Kosary, C.L., Krapcho, M., Neyman, N., Aminou, R., Waldron, W.,... Edwards, B.K. (Eds.). (2010). SEER cancer statistics review, 1975-2007. Bethesda, MD: National Cancer Institute. Retrieved from http://seer.cancer.gov/csr/1975_2007
3. American Cancer Society. (2010). Cancer facts and figures, 2010. Atlanta, GA: Author.
4. Baber, R., Hickey, M., & Kwik, M. (2005). Therapy for menopausal symptoms during and after treatment for breast cancer: Safety considerations. Drug Safety, 28, 1085-1100.
5. Barton, D.L., Loprinzi, C.L., Quella, S.K., Sloan, J.A., Veeder, M.H., Egner, J.R.,... Novotny, P. (1998). Prospective evaluation of vitamin E for hot flashes in breast cancer survivors. Journal of Clinical Oncology, 16, 495-500.
6. Batur, P., Blixen, C.E., Moore, H.C., Thacker, H.L., & Xu, M. (2006). Menopausal hormone therapy (HT) in patients with breast cancer. Maturitas, 53, 123-132. doi: 10.1016/j.maturitas.2005.03.004
7. Bertelli, G., Venturini, M., Del Mastro, L., Bergaglio, M., Sismondi, P., Biglia, N.,... Rosso, R. (2002). Intramuscular depot medroxyprogesterone versus oral megestrol for the control of postmenopausal hot flashes in breast cancer patients: A randomized study. Annals of Oncology, 13, 883-888. doi: 10.1093/annonc/mdf151
8. Biglia, N., Kubatzki, F., Sgandurra, P., Ponzone, R., Marenco, D., Peano, E., & Sismondi, P. (2007). Mirtazapine for the treatment of hot flushes in breast cancer survivors: A prospective pilot trial. Breast Journal, 13, 490-495. doi: 10.1111/j.1524-4741.2007.00470.x
9. Biglia, N., Sgandurra, P., Peano, E., Marenco, D., Moggio, G., Bounous, V., & Sismondi, P. (2009). Non-hormonal treatment of hot flushes in breast cancer survivors: Gabapentin vs. vitamin E. Climacteric, 12, 310-318. doi: 10.1080/13697130902736921
10. Biglia, N., Torta, R., Roagna, R., Maggiorotto, F., Cacciari, F., Ponzone, R.,... Sismondi, P. (2005). Evaluation of low-dose venlafaxine hydrochloride for the therapy of hot flushes in breast cancer survivors. Maturitas, 52, 78-85. doi: 10.1016/j.maturitas.2005.01.001
11. Boekhout, A.H., Beijnen, J.H., & Schellens, J.H. (2006). Symptoms and treatment in cancer therapy-induced early menopause. Oncologist, 11, 641-654. doi: 10.1634/theoncologist.11-6-641
12. Buijs, C., Mom, C.H., Willemse, P.H., Marike Boezen, H., Maurer, J.M., Wymenga, A.N., & Mourits, M.J. (2009). Venlafaxine versus clonidine for the treatment of hot flashes in breast cancer patients: A double-blind, randomized cross-over study. Breast Cancer Research and Treatment, 115, 573-580. doi: 10.1007/s10549-008-0138-7
13. Carpenter, J.S. (2005). State of the science: Hot flashes and cancer. Part 1: Definition, scope, impact, physiology, and measurement. Oncology Nursing Forum, 32, 959-968. doi: 10.1188/05.ONF.959-968
14. Carpenter, J.S., Storniolo, A.M., Johns, S., Monahan, P.O., Azzouz, F., Elam, J.L.,... Shelton, R.C. (2007). Randomized, double-blind, placebo-controlled crossover trials of venlafaxine for hot flashes after breast cancer. Oncologist, 12, 124-135.
15. Carson, J.W., Carson, K.M., Porter, L.S., Keefe, F.J., & Seewaldt, V.L. (2009). Yoga of Awareness program for menopausal symptoms in breast cancer survivors: Results from a randomized trial. Supportive Care in Cancer, 17, 1301-1309. doi: 10.1007/s00520-009-0587-5
16. Clover, A., & Ratsey, D. (2002). Homeopathic treatment of hot flushes: A pilot study. Homeopathy, 91, 75-79.
17. Deng, G., Vickers, A., Yeung, S., D'Andrea, G.M., Xiao, H., Heerdt, A.S.,... Cassileth, B. (2007). Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients. Journal of Clinical Oncology, 25, 5584-5590. doi: 10.1200/JCO.2007.12.0774
18. Elkins, G., Marcus, J., Palamara, L., & Stearns, V. (2004). Can hypnosis reduce hot flashes in breast cancer survivors? A literature review. American Journal of Clinical Hypnosis, 47, 29-42.
19. Elkins, G., Marcus, J., Stearns, V., Perfect, M., Hasan Rajab, M., Ruud, C., & Keith, T. (2008). Randomized trial of a hypnosis intervention for treatment of hot flashes among breast cancer survivors. Journal of Clinical Oncology, 26, 5022-5026.
20. Elkins, G., Marcus, J., Stearns, V., & Rajab, M.H. (2007). Pilot evaluation of hypnosis for the treatment of hot flashes in breast cancer survivors. Psycho-Oncology, 16, 487-492. doi: 10.1002/pon.1096
21. Engstrom, C.A. (2008). Hot flashes in prostate cancer: State of the science. American Journal of Men's Health, 2, 122-132.
22. Fenlon, D.R., Corner, J.L., & Haviland, J.S. (2008). A randomized controlled trial of relaxation training to reduce hot flashes in women with primary breast cancer. Journal of Pain and Symptom Management, 35, 397-405. doi: 10.1016/j.jpainsymman.2007.05.014
23. Filshie, J., Bolton, T., Browne, D., & Ashley, S. (2005). Acupuncture and self acupuncture for long-term treatment of vasomotor symptoms in cancer patients-Audit and treatment algorithm. Acupuncture in Medicine, 23, 171-180. doi: 10.1136/aim.23.4.171
24. Finck, G., Barton, D.L., Loprinzi, C.L., Quella, S.K., & Sloan, J.A. (1998). Definitions of hot flashes in breast cancer survivors. Journal of Pain and Symptom Management, 16, 327-333.
25. Frisk, J. (2010). Managing hot flushes in men after prostate cancer-A systematic review. Maturitas, 65, 15-22.
26. Frisk, J., Carlhäll, S., Källström, A.C., Lindh-Astrand, L., Malmström, A., & Hammar, M. (2008). Long-term follow-up of acupuncture and hormone therapy on hot flushes in women with breast cancer: A prospective, randomized, controlled multicenter trial. Climacteric, 11, 166-174. doi: 10.1080/13697130801958709
27. Gerber, G.S., Zagaja, G.P., Ray, P.S., & Rukstalis, D.B. (2000). Transdermal estrogen in the treatment of hot flashes in men with prostate cancer. Urology, 55, 97-101.
28. Goldberg, R.M., Loprinzi, C.L., O'Fallon, J.R., Veeder, M.H., Miser, A.W., Mailliard, J.A.,... Burnham, N.L. (1994). Transdermal clonidine for ameliorating tamoxifen-induced hot flashes. Journal of Clinical Oncology, 12, 155-158.
29. Goodwin, J.W., Green, S.J., Moinpour, C.M., Bearden, J.D., III, Giguere, J.K., Jiang, C.S.,... Albain, K.S. (2008). Phase III randomized placebo-controlled trial of two doses of megestrol acetate as treatment for menopausal symptoms in women with breast cancer: Southwest Oncology Group study 9626. Journal of Clinical Oncology, 26, 1650-1656.
30. Hammar, M., Frisk, J., Grimås, O., Höök, M., Spetz, A.C., & Wyon, Y. (1999). Acupuncture treatment of vasomotor symptoms in men with prostatic carcinoma: A pilot study. Journal of Urology, 161, 853-856. doi: 10.1016/S0022-5347(01)61789-0
31. Harding, C., Harris, A., & Chadwick, D. (2008). Auricular acupuncture: A novel treatment for vasomotor symptoms associated with luteinizing-hormone releasing hormone agonist treatment for prostate cancer. BJU International, 103, 186-190.
32. Henry, N.L., Stearns, V., Flockhart, D.A., Hayes, D.F., & Riba, M. (2008). Drug interactions and pharmacogenomics in the treatment of breast cancer and depression. American Journal of Psychiatry, 165, 1251-1255. doi: 10.1176/appi.ajp.2008.08040482
33. Hernández Muñoz, G., & Pluchino, S. (2003). Cimicifuga racemosa for the treatment of hot flushes in women surviving breast cancer. Maturitas, 44(Suppl. 1), S59-S65.
34. Hervik, J., & Mjåland, O. (2009). Acupuncture for the treatment of hot flashes in breast cancer patients. A randomized, controlled trial. Breast Cancer Research and Treatment, 116, 311-316.
35. Holmberg, L., Iversen, O.E., Rudenstam, C.M., Hammar, M., Kumpulainen, E., Jaskiewicz, J.,... Maenpaa, J. (2008). Increased risk of recurrence after hormone replacement therapy in breast cancer survivors. Journal of the National Cancer Institute, 100, 475-482. doi: 10.1093/jnci/djn058
36. Howell, A., Cuzick, J., Baum, M., Buzdar, A., Dowsett, M., Forbes, J.F.,... Tobias, J.S. (2005). Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet, 365, 60-62.
37. Jacobs, J., Herman, P., Heron, K., Olsen, S., & Vaughters, L. (2005). Homeopathy for menopausal symptoms in breast cancer survivors: A preliminary randomized controlled trial. Journal of Alternative and Complementary Medicine, 11(1), 21-27.
38. Jacobson, J.S., Troxel, A.B., Evans, J., Klaus, L., Vahdat, L., Kinne, D., & Grann, V.R. (2001). Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer. Journal of Clinical Oncology, 19, 2739-2745.
39. Jemal, A., Siegel, R., Xu, J., & Ward, E. (2010). Cancer statistics, 2010. CA: A Cancer Journal for Clinicians, 60, 277-300. doi: 10.3322/caac.20073
40. Kelly, C.M., Juurlink, D.N., Gomes, T., Duong-Hua, M., Pritchard, K.I., Austin, P.C., & Paszat, L.F. (2010). Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: A population based cohort study. BMJ, 340, c693.
41. Kimmick, G.G., Lovato, J., McQuellon, R., Robinson, E., & Muss, H.B. (2006). Randomized, double-blind, placebo-controlled, crossover study of sertraline (Zoloft) for the treatment of hot flashes in women with early stage breast cancer taking tamoxifen. Breast Journal, 12, 114-122. doi: 10.1111/j.1075-122X.2006.00218.x
42. Kroiss, R., Fentiman, I.S., Helmond, F.A., Rymer, J., Foidart, J.M., Bundred, N.,... Kubista, E. (2005). The effect of tibolone in postmenopausal women receiving tamoxifen after surgery for breast cancer: A randomised, double-blind, placebo-controlled trial. BJOG: An International Journal of Obstetrics and Gynecology, 112, 228-233. doi: 10.1111/j.1471-0528.2004.00309.x
43. Lee, M.S., Kim, K.H., Shin, B.C., Choi, S.M., & Ernst, E. (2009). Acupuncture for treating hot flushes in men with prostate cancer: A systematic review. Supportive Care in Cancer, 17, 763-770.
44. Lipov, E.G., Joshi, J.R., Sanders, S., Wilcox, K., Lipov, S., Xie, H., & Slavin, K. (2008). Effects of stellate-ganglion block on hot flushes and night awakenings in survivors of breast cancer: A pilot study. Lancet, 9, 523-532. doi: 10.1016/S1470-2045(08)70131-1
45. Loibl, S., Schwedler, K., von Minckwitz, G., Strohmeier, R., Mehta, K.M., & Kaufmann, M. (2007). Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients-A double blind, randomized study. Annals of Oncology, 18, 689-693.
46. Loprinzi, C.L., & Barton, D.L. (2009). Gadgets for measuring hot flashes: Have they become the gold standard? Journal of Supportive Oncology, 7, 136-137.
47. Loprinzi, C.L., Goldberg, R.M., O'Fallon, J.R., Quella, S.K., Miser, A.W., Mynderse, L.A.,... Dose, M. (1994). Transdermal clonidine for ameliorating post-orchiectomy hot flashes. Journal of Urology, 151, 634-636.
48. Loprinzi, C.L., Kugler, J.W., Sloan, J.A., Mailliard, J.A., LaVasseur, B.I., Barton, D.L.,... Christensen, B.J. (2000). Venlafaxine in management of hot flashes in survivors of breast cancer: A randomised controlled trial. Lancet, 356, 2059-2063.
49. Loprinzi, C.L., Sloan, J.A., Perez, E.A., Quella, S.K., Stella, P.J., Mailliard, J.A.,... Rummans, T.A. (2002). Phase III evaluation of fluoxetine for treatment of hot flashes. Journal of Clinical Oncology, 20, 1578-1583. doi: 10.1200/JCO.20.6.1578
50. Loprinzi, C.L., Sloan, J.A., Stearns, V., Slack, R., Iyengar, M., Diekmann, B., & Novotny, P. (2009). Newer antidepressants and gabapentin for hot flashes: An individual patient pooled analysis. Journal of Clinical Oncology, 27, 2831-2837.
51. MacGregor, C.A., Canney, P.A., Patterson, G., McDonald, R., & Paul, J. (2005). A randomised double-blind controlled trial of oral soy supplements versus placebo for treatment of menopausal symptoms in patients with early breast cancer. European Journal of Cancer, 41, 708-714. doi: 10.1016/j.ejca.2005.01.005
52. Mitchell, S.A., & Friese, C.R. (n.d.). ONS PEP (Putting Evidence into Practice) Weight of evidence classification schema: Decision rules for summative evaluation of a Body of Evidence. Retrieved from http://www.ons.org/Research/media/ons/docs/research/outcomes/weight-of-evidence-table.pdf
53. National Cancer Institute. (2010a). Dictionary of cancer terms. Retrieved from http://www.cancer.gov/dictionary
54. National Cancer Institute. (2010b). SEER stat fact sheets: Breast. Retrieved from http://seer.cancer.gov/statfacts/html/breast.html
55. National Cancer Institute. (2010c). SEER stat fact sheets: Prostate. Retrieved from http://seer.cancer.gov/statfacts/html/prost.html
56. National Center for Complementary and Alternative Medicine. (2011). Health topics A-Z. Retrieved from http://nccam.nih.gov/health/atoz.htm
57. Nedstrand, E., Wijma, K., Wyon, Y., & Hammar, M. (2005). Vasomotor symptoms decrease in women with breast cancer randomized to treatment with applied relaxation or electro-acupuncture: A preliminary study. Climacteric, 8, 243-250.
58. NIH State-of-the-Science Conference Statement on management of menopause-related symptoms. (2005). NIH Consensus and State-of-the-Science Statements, 22(1), 1-38.
59. Nikander, E., Metsä-Heikkilä, M., Ylikorkala, O., & Tiitinen, A. (2004). Effects of phytoestrogens on bone turnover in postmenopausal women with a history of breast cancer. Journal of Clinical Endocrinology and Metabolism, 89, 1207-1212.
60. Pandya, K.J., Morrow, G.R., Roscoe, J.A., Zhao, H., Hickok, J.T., Pajon, E.,... Flynn, P.J. (2005). Gabapentin for hot flashes in 420 women with breast cancer: A randomised double-blind placebo-controlled trial. Lancet, 366, 818-824. doi: 10.1016/S0140-6736(05)67215-7
61. Pandya, K.J., Raubertas, R.F., Flynn, P.J., Hynes, H.E., Rosenbluth, R.J., Kirshner, J.J.,... Morrow, G.R. (2000). Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: A University of Rochester Cancer Center Community Clinical Oncology Program study. Annals of Internal Medicine, 16, 788-793.
62. Pockaj, B.A., Gallagher, J.G., Loprinzi, C.L., Stella, P.J., Barton, D.L., Sloan, J.A., & Fauq, A.H. (2006). Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes: NCCTG trial N01CC1. Journal of Clinical Oncology, 24, 2836-2841. doi: 10.1200/JCO.2005.05.4296
63. Quella, S.K., Loprinzi, C.L., Barton, D.L., Knost, J.A., Sloan, J.A., LaVasseur, B.I., & Novotny, P.J. (2000). Evaluation of soy phytoestrogens for the treatment of hot flashes in breast cancer survivors: A North Central Cancer Treatment Group trial. Journal of Clinical Oncology, 18, 1068-1074.
64. Schover, L.R., Jenkins, R., Sui, D., Adams, J.H., Marion, M.S., & Jackson, K.E. (2006). Randomized trial of peer counseling on reproductive health in African American breast cancer survivors. Journal of Clinical Oncology, 24, 1620-1626. doi: 10.1200/JCO.2005.04.7159
65. Sharma, P., Wisniewski, A., Braga-Basaria, M., Xu, X., Yep, M., Denmeade, S., & Basaria, S. (2009). Lack of an effect of high dose isoflavones in men with prostate cancer undergoing androgen deprivation therapy. Journal of Urology, 182, 2265-2272.
66. Sloan, J.A., Loprinzi, C. L., Novotny, P.J., Barton, D.L., LaVasseur, B.I., & Windschitl, H. (2001). Methodologic lessons learned from hot flash studies. Journal of Clinical Oncology, 19, 4280-4290.
67. Stearns, V., Slack, R., Greep, N., Henry-Tilman, R., Osborne, M., Bunnel, C., & Isaacs, C. (2005). Paroxetine is an effective treatment for hot flashes: Results from a prospective randomized clinical trial. Journal of Clinical Oncology, 23, 6919-6930.
68. Thompson, E.A., & Reilly, D. (2003). The homeopathic approach to the treatment of symptoms of oestrogen withdrawal in breast cancer patients: A prospective observational study. Homeopathy, 92, 131-134. doi: 10.1016/S1475-4916(03)00035-3
69. Towlerton, G., Filshie, J., O'Brien, M., & Duncan, A. (1999). Acupuncture in the control of vasomotor symptoms caused by tamoxifen. Palliative Medicine, 13, 445. doi: 10.1177/026921639901300516
70. Van Patten, C.L., Olivotto, I.A., Chambers, G.K., Gelmon, K.A., Hislop, T.G., Templeton, E.,... Prior, J.C. (2002). Effect of soy phytoestrogens on hot flashes in postmenopausal women with breast cancer: A randomized, controlled clinical trial. Journal of Clinical Oncology, 20, 1449-1455. doi: 10.1200/JCO.20.6.1449
71. Walker, E.M., Rodriguez, A.I., Kohn, B., Ball, R.M., Pegg, J., Pocock, J.R.,... Levine, R.A. (2010). Acupuncture versus venlafaxine for the management of vasomotor symptoms in patients with hormone receptor-positive breast cancer: A randomized controlled trial. Journal of Clinical Oncology, 28, 634-640. doi: 10.1200/JCO.2009.23.5150
72. Younus, J., Simpson, I., Collins, A., & Wang, X. (2003). Mind control of menopause. Women's Health Issues, 13(2), 74-78.