Reversible covalent binding of neratinib to human serum albumin in vitro.

Drug metabolism letters

Volumn 4, Issue 4, 2010, Pages 220-227

  Chandrasekaran, Appavu ^a   Shen, L ^b   Lockhead, Susan ^b   Oganesian, Aram ^b   Wang, Jianyao ^b   Scatina, JoAnn ^b  

^a PFIZER INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARBON; N (4 (3 CHLORO 4 (2 PYRIDINYLMETHOXY)ANILINO) 3 CYANO 7 ETHOXY 6 QUINOLYL) 4 (DIMETHYLAMINO) 2 BUTENAMIDE; N-(4-(3-CHLORO-4-(2-PYRIDINYLMETHOXY)ANILINO)-3-CYANO-7-ETHOXY-6-QUINOLYL)-4-(DIMETHYLAMINO)-2-BUTENAMIDE; PROTEIN KINASE INHIBITOR; QUINOLINE DERIVATIVE; SERUM ALBUMIN;

ARTICLE; BINDING COMPETITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KINETICS; METABOLISM; PH; PROTEIN BINDING; TEMPERATURE;

ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; QUINOLINES; SERUM ALBUMIN; TEMPERATURE;

EID: 79953332009     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231210792928206     Document Type: Article

References (0)