Do holes in the lungs beget holes in the bones?

American Journal of Respiratory and Critical Care Medicine

Volumn 183, Issue 7, 2011, Pages 835-837

  Cooper, Christopher B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CORTICOSTEROID; GELATINASE B; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

BONE DENSITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMORBIDITY; DIETARY INTAKE; DISEASE ASSOCIATION; EDITORIAL; ENERGY EXPENDITURE; HUMAN; OSTEOPENIA; OSTEOPOROSIS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN METABOLISM; RISK FACTOR; WEIGHT REDUCTION;

BONE DENSITY; CAUSALITY; COMORBIDITY; FEMALE; HUMANS; INCIDENCE; MALE; OSTEOPOROSIS; PROGNOSIS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX;

EID: 79953318801     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201011-1837ED     Document Type: Editorial

References (15)

1. Decramer M, Rennard S, Troosters T, Mapel DW, Giardino N, Mannino D, Wouters E, Sethi S, Cooper CB. COPD as a lung disease with systemic consequences-clinical impact, mechanisms, and potential for early intervention. COPD 2008;5:235-256.
2. Schols AM, Soeters PB, Dingemans AM, Mostert R, Frantzen PJ, Wouters EF. Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation. Am Rev Respir Dis 1993;147:1151-1156. (Pubitemid 23149871)
3. Schols AM, Slangen J, Volovics L, Wouters EF. Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998;157:1791-1797.
4. Eid AA, Ionescu AA, Nixon LS, Lewis-Jenkins V, Matthews SB, Griffiths TL, Shale DJ. Inflammatory response and body composition in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001;164:1414-1418. (Pubitemid 33124019)
5. Bolton CE, Ionescu AA, Shiels KM, Pettit RJ, Edwards PH, Stone MD, Nixon LS, Evans WD, Griffiths TL, Shale DJ. Associated loss of fat-free mass and bone mineral density in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004;170:1286-1293. (Pubitemid 39657192)
6. Bolton CE, Stone MD, Edwards PH, Duckers JM, Evans WD, Shale DJ. Circulating matrix metalloproteinase-9 and osteoporosis in patients with chronic obstructive pulmonary disease. Chron Respir Dis 2009;6:81-87.
7. Finlay GA, O'Driscoll LR, Russell KJ, D'Arcy EM, Masterson JB, FitzGerald MX, O'Connor CM. Matrix metalloproteinase expression and production by alveolar macrophages in emphysema. Am J Respir Crit Care Med 1997;156:240-247. (Pubitemid 27293196)
8. Engelen MP, Deutz NE, Wouters EF, Schols AM. Enhanced levels of whole-body protein turnover in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000;162:1488-1492.
9. Engelen MP, Deutz NE, Mostert R, Wouters EF, Schols AM. Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema. Am J Clin Nutr 2003;77:868-874.
10. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO workshop summary, updated 2009. London: Global Initiative for Chronic Obstructive Lung Disease (GOLD); 2009. (Accessed Sep. 24, 2010). Available from: http://www.goldcopd.com.
11. Bon J, Fuhrman CR, Weissfeld JL, Duncan SR, Branch RA, Chang CC, Zhang Y, Leader JK, Gur D, Greenspan SL, et al. Radiographic emphysema predicts low bone mineral density in a tobacco-exposed cohort. Am J Respir Crit Care Med 2011;183:885-890.
12. Leichter I, Weinreb A, Hazan G, Loewinger E, Robin GC, Steinberg R, Menczel J, Makin M. The effect of age and sex on bone density, bone mineral content and cortical index. Clin Orthop Relat Res 1981;232-239. (Pubitemid 11096524)
13. Hedlund LR, Gallagher JC. The effect of age and menopause on bone mineral density of the proximal femur. J Bone Miner Res 1989;4:639-642. (Pubitemid 19224564)
14. Sin DD, Man JP, Man SF. The risk of osteoporosis in Caucasian men and women with obstructive airways disease. Am J Med 2003;114:10-14. (Pubitemid 36126509)
15. Ferguson GT, Calverley PM, Anderson JA, Jenkins CR, Jones PW, Willits LR, Yates JC, Vestbo J, Celli B. Prevalence and progression of osteoporosis in patients with COPD: results from the TOwards a Revolution in COPD Health study. Chest 2009;136:1456-1465.