-
2
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty, KT, Puzanov, I, Kim, KB, Ribas, A, McArthur, GA, Sosman, JA et al. (2010). Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 363: 809-819.
-
(2010)
N Engl J Med
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
Ribas, A.4
McArthur, G.A.5
Sosman, J.A.6
-
4
-
-
78650008177
-
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K
-
Villanueva, J, Vultur, A, Lee, JT, Somasundaram, R, Fukunaga-Kalabis, M, Cipolla, AK et al. (2010). Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. Cancer Cell 18: 683-695.
-
(2010)
Cancer Cell
, vol.18
, pp. 683-695
-
-
Villanueva, J.1
Vultur, A.2
Lee, J.T.3
Somasundaram, R.4
Fukunaga-Kalabis, M.5
Cipolla, A.K.6
-
5
-
-
77952502408
-
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth
-
Roesch, A, Fukunaga-Kalabis, M, Schmidt, EC, Zabierowski, SE, Brafford, PA, Vultur, A et al. (2010). A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth. Cell 141: 583-594.
-
(2010)
Cell
, vol.141
, pp. 583-594
-
-
Roesch, A.1
Fukunaga-Kalabis, M.2
Schmidt, E.C.3
Zabierowski, S.E.4
Brafford, P.A.5
Vultur, A.6
-
6
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
Nazarian, R, Shi, H, Wang, Q, Kong, X, Koya, RC, Lee, H et al. (2010). Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature 468: 973-977.
-
(2010)
Nature
, vol.468
, pp. 973-977
-
-
Nazarian, R.1
Shi, H.2
Wang, Q.3
Kong, X.4
Koya, R.C.5
Lee, H.6
-
7
-
-
78650309875
-
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
-
Johannessen, CM, Boehm, JS, Kim, SY, Thomas, SR, Wardwell, L, Johnson, LA et al. (2010). COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 468: 968-972.
-
(2010)
Nature
, vol.468
, pp. 968-972
-
-
Johannessen, C.M.1
Boehm, J.S.2
Kim, S.Y.3
Thomas, S.R.4
Wardwell, L.5
Johnson, L.A.6
-
8
-
-
43949156757
-
CD20: A regulator of cell-cycle progression of B lymphocytes
-
DOI 10.1016/0167-5699(94)90276-3
-
Tedder, TF and Engel, P (1994). CD20: a regulator of cell-cycle progression of B lymphocytes. Immunol Today 15: 450-454. (Pubitemid 24272191)
-
(1994)
Immunology Today
, vol.15
, Issue.9
, pp. 450-454
-
-
Tedder, T.F.1
Engel, P.2
-
9
-
-
79952302092
-
Eradication of melanomas by targeted elimination of a minor subset of tumor cells
-
Schmidt, P, Kopecky, C, Hombach, A, Zigrino, P, Mauch, C and Abken, H (2011). Eradication of melanomas by targeted elimination of a minor subset of tumor cells. Proc Natl Acad Sci USA 108: 2474-2479.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 2474-2479
-
-
Schmidt, P.1
Kopecky, C.2
Hombach, A.3
Zigrino, P.4
Mauch, C.5
Abken, H.6
-
10
-
-
38349165576
-
Identifi- cation of cells initiating human melanomas
-
Schatton, T, Murphy, GF, Frank, NY, Yamaura, K, Waaga-Gasser, AM, Gasser, M et al. (2008). Identifi- cation of cells initiating human melanomas. Nature 451: 345-349.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
Yamaura, K.4
Waaga-Gasser, A.M.5
Gasser, M.6
-
11
-
-
27144557960
-
A tumorigenic subpopulation with stem cell properties in melanomas
-
DOI 10.1158/0008-5472.CAN-05-1343
-
Fang, D, Nguyen, TK, Leishear, K, Finko, R, Kulp, AN, Hotz, S et al. (2005). A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 65: 9328-9337. (Pubitemid 41508000)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9328-9337
-
-
Fang, D.1
Nguyen, T.K.2
Leishear, K.3
Finko, R.4
Kulp, A.N.5
Hotz, S.6
Van Belle, P.A.7
Xu, X.8
Elder, D.E.9
Herlyn, M.10
-
12
-
-
77954238710
-
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
-
Boiko, AD, Razorenova, OV, van de Rijn, M, Swetter, SM, Johnson, DL, Ly, DP et al. (2010). Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 466: 133-137.
-
(2010)
Nature
, vol.466
, pp. 133-137
-
-
Boiko, A.D.1
Razorenova, O.V.2
Van De Rijn, M.3
Swetter, S.M.4
Johnson, D.L.5
Ly, D.P.6
-
13
-
-
60149109533
-
Looking ahead in cancer stem cell research
-
Dick, JE (2009). Looking ahead in cancer stem cell research. Nat Biotechnol 27: 44-46.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 44-46
-
-
Dick, J.E.1
-
14
-
-
0026326823
-
Human high molecular weight-melanoma associated antigen mimicry by an anti-idiotypic antibody: Characterization of the immunogenicity and the immune response to the mouse monoclonal antibody IMel-1
-
Chattopadhyay, P, Kaveri, SV, Byars, N, Starkey, J, Ferrone, S and Raychaudhuri, S (1991). Human high molecular weight-melanoma associated antigen mimicry by an anti-idiotypic antibody: characterization of the immunogenicity and the immune response to the mouse monoclonal antibody IMel-1. Cancer Res 51: 6045-6051.
-
(1991)
Cancer Res
, vol.51
, pp. 6045-6051
-
-
Chattopadhyay, P.1
Kaveri, S.V.2
Byars, N.3
Starkey, J.4
Ferrone, S.5
Raychaudhuri, S.6
-
15
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana, E, Shackleton, M, Sabel, MS, Fullen, DR, Johnson, TM and Morrison, SJ (2008). Efficient tumour formation by single human melanoma cells. Nature 456: 593-598.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
16
-
-
78249250559
-
Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
-
Quintana, E, Shackleton, M, Foster, HR, Fullen, DR, Sabel, MS, Johnson, TM et al. (2010). Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 18: 510-523.
-
(2010)
Cancer Cell
, vol.18
, pp. 510-523
-
-
Quintana, E.1
Shackleton, M.2
Foster, H.R.3
Fullen, D.R.4
Sabel, M.S.5
Johnson, T.M.6
-
17
-
-
33646440024
-
Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
-
Lamers, CH, Sleijfer, S, Vulto, AG, Kruit, WH, Kliffen, M, Debets, R et al. (2006). Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol 24: e20-22.
-
(2006)
J Clin Oncol
, vol.24
-
-
Lamers, C.H.1
Sleijfer, S.2
Vulto, A.G.3
Kruit, W.H.4
Kliffen, M.5
Debets, R.6
-
18
-
-
33750699642
-
A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
-
DOI 10.1158/1078-0432.CCR-06-1183
-
Kershaw, MH, Westwood, JA, Parker, LL, Wang, G, Eshhar, Z, Mavroukakis SA et al. (2006). A phase I study on adoptive immunotherapy using genemodified T cells for ovarian cancer. Clin Cancer Res 12: 6106-6115. (Pubitemid 44703776)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.PART 1
, pp. 6106-6115
-
-
Kershaw, M.H.1
Westwood, J.A.2
Parker, L.L.3
Wang, G.4
Eshhar, Z.5
Mavroukakis, S.A.6
White, D.E.7
Wunderlich, J.R.8
Canevari, S.9
Rogers-Freezer, L.10
Chen, C.C.11
Yang, J.C.12
Rosenberg, S.A.13
Hwu, P.14
-
19
-
-
16444363534
-
Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: Implications in chemosensitization and therapeutic intervention
-
DOI 10.1038/sj.onc.1208349
-
Jazirehi, AR and Bonavida, B (2005). Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention. Oncogene 24: 2121-2143. (Pubitemid 40516580)
-
(2005)
Oncogene
, vol.24
, Issue.13
, pp. 2121-2143
-
-
Jazirehi, A.R.1
Bonavida, B.2
-
20
-
-
69449096005
-
Heterogeneity in cancer: Cancer stem cells versus clonal evolution
-
Shackleton, M, Quintana, E, Fearon, ER and Morrison, SJ (2009). Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 138: 822-829.
-
(2009)
Cell
, vol.138
, pp. 822-829
-
-
Shackleton, M.1
Quintana, E.2
Fearon, E.R.3
Morrison, S.J.4
|