Synthesis and Biological Evaluation Of Potent Antihypertensive Activity: 2-[(Substituted-phenyl amino)-phenyl-methyl]-1-[2'-(1H-tetrazol-5-Yl) biphenyl-3-ylmethyl]-1H-benzoimidazol-5-ylamine Derivatives

International Journal of Advances in Pharmaceutical Sciences

Volumn 1, Issue 3, 2010, Pages 284-298

  Sharma, M C ^a   Kohli, D V ^a   Sharma, Smita ^b  

^a DR H S GOUR UNIVERSITY   (India)

^b Department of Chemistry Yadhunath Mahavidyalya ^*  (India)

Author keywords

Angiotension ii; Antihypertensive agents; Benzimidazoles; Biphenyl tetrazole

Indexed keywords

2 (ALPHA BROMO BENZYL) BENZIMIDAZOLE; 2 (ALPHA HYDROXY BENZYL) BENZIMIDAZOLE; 2 [(2 CHLORO PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(2 ETHOXY PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(2 METHOXY PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(2 NITRO PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(3 CHLORO PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(3 ETHOXY PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(3 METHOXY PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(4 CHLORO PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(4 ETHOXY PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; 2 [(4 METHOXY PHENYL AMINO) PHENYL METHYL] 1[2' (1H TETRAZOL 5 YL) BIPHENYL 3 YLMETHYL] 1H BENZOIMIDAZOL 5 YLAMINE DERIVATIVE; ANGIOTENSIN II; BENZIMIDAZOLE DERIVATIVE; CANDESARTAN; EPROSARTAN; IRBESARTAN; LOSARTAN; MILFASARTAN; NITRIC ACID; OLMESARTAN; SAPRISARTAN; SULFURIC ACID; TASOSARTAN; TELMISARTAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALSARTAN; ZINC CHLORIDE; ZOLZSARTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE MEASUREMENT; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYPERTENSION; INFRARED SPECTROSCOPY; MALE; MELTING POINT; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 79953312712     PISSN: None     EISSN: 09761055     Source Type: Journal    
DOI: 10.5138/ijaps.2010.0976.1055.01034     Document Type: Article

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