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Volumn 15, Issue 1, 2011, Pages 227-231

Synthesis of 5-aryl-1,3-dimethyl-6-(alkyl- or aryl-amino) furo [2,3-d]pyrimidine derivatives by reaction between isocyanides and pyridinecarbaldehydes in the presence of 1,3-dimethylbarbituric acid

Author keywords

1,3 Dimethylbarbituric acid; Furo 2,3 d pyrimidine derivatives; Isocyanides; Pyridinecarbaldehyde derivatives

Indexed keywords

6 (2,6 DIMETHYLPHENYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 2 YL)FURO(2,3 D)PYRIMIDINE 2,4(1H,3H)DIONE; 6 (CYCLOHEXYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 2 YL)FURO(2,3 D)PYRIMIDINE 2,4(1H,3H)DIONE; 6 (CYCLOHEXYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 4 YL)FURO(2,3 D)PYRIMIDINE 2,4(1H,3H)DIONE; 6 (ETHYLACETYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 2 YL)FURO(2,3 D)PYRIMIDINE 2,4(1H,3H)DIONE; 6 (ETHYLACETYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 3 YL)FURO(2,3 D)PYRIMIDINE 2,4(1H,3H)DIONE; 6 (TERT BUTYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 2 YL)FURO[2,3 D]PYRIMIDINE 2,4(1H,3H)DIONE; 6 (TERT BUTYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 3 YL)FURO(2,3 D)PYRIMIDINE 2,4(1H,3H)DIONE; 6 (TERT BUTYLAMINO) 1,3 DIMETHYL 5 (PYRIDIN 4 YL)FURO(2,3 D)PYRIMIDINE 2,4 (1H,3H)DIONE; ALDEHYDE DERIVATIVE; BARBITURIC ACID; CYANIDE; DICHLOROMETHANE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79953311511     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-010-9257-2     Document Type: Article
Times cited : (20)

References (21)
  • 3
    • 0033186014 scopus 로고    scopus 로고
    • Antitumoral activity of new pyrimidine derivatives of sesquiterpene lactones
    • Quintero A, Pelcastre A, Solano JD, Guzmán A, Diaz E (1999) Antitumoral activity of new pyrimidine derivatives of sesquiterpene lactones. J Pharm Sci 2:108-112
    • (1999) J Pharm Sci , vol.2 , pp. 108-112
    • Quintero, A.1    Pelcastre, A.2    Solano, J.D.3    Guzmán, A.4    Diaz, E.5
  • 4
    • 0035540928 scopus 로고    scopus 로고
    • Approaches to fused pyrimidine derivatives by the pyrimidine construction and their application to synthesis of purines
    • Ostrowski S (2001) Approaches to fused pyrimidine derivatives by the pyrimidine construction and their application to synthesis of purines. Pol J Chem 75:1661-1687
    • (2001) Pol J Chem , vol.75 , pp. 1661-1687
    • Ostrowski, S.1
  • 5
    • 2442670191 scopus 로고    scopus 로고
    • An expeditious synthesis of 3,4-dihydrobenzo[2,3-d]pyrimidines using inorganic solid supports
    • Kidwai M, Deo Mishra A (2004) An expeditious synthesis of 3,4-dihydrobenzo[2,3-d]pyrimidines using inorganic solid supports. J Serb Chem Soc 69:247-254
    • (2004) J Serb Chem Soc , vol.69 , pp. 247-254
    • Kidwai, M.1    Deo Mishra, A.2
  • 6
    • 0016711123 scopus 로고
    • Application of pyridinium salts derived of barbituric acid in Kröhnke's reaction
    • Prelicz D, Kasperek L (1975) Application of pyridinium salts derived of barbituric acid in Kröhnke's reaction. Pol J Pharmacol Pharm 27:327-334
    • (1975) Pol J Pharmacol Pharm , vol.27 , pp. 327-334
    • Prelicz, D.1    Kasperek, L.2
  • 7
    • 0035996085 scopus 로고    scopus 로고
    • Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication
    • Balzarini J, McGuigan C (2002) Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication. J Antimicrob Chemother 50: 5-9. doi:10.1093/jac/dkf037 (Pubitemid 34785248)
    • (2002) Journal of Antimicrobial Chemotherapy , vol.50 , Issue.1 , pp. 5-9
    • Balzarini, J.1    McGuigan, C.2
  • 10
    • 24344507274 scopus 로고    scopus 로고
    • Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein
    • DOI 10.1016/j.bmcl.2005.05.067, PII S0960894X05006724
    • Manna F, Chimenti F, Fioravanti R, Bolasco A, Secci D, Chimenti P, Ferlini C, Scambia G (2005) Synthesis of some pyrazoles derivatives and preliminary investigation of their affinity binding to p-gylcoprotein. Bioorg Med Chem Lett 15:4632-4635. doi:10.1016/j.bmcl.2005.05.067 (Pubitemid 41253909)
    • (2005) Bioorganic and Medicinal Chemistry Letters , vol.15 , Issue.20 , pp. 4632-4635
    • Manna, F.1    Chimenti, F.2    Fioravanti, R.3    Bolasco, A.4    Secci, D.5    Chimenti, P.6    Ferlini, C.7    Scambia, G.8
  • 11
    • 14844311316 scopus 로고    scopus 로고
    • In vitro antibacterial activity of ten series of substituted quinazolines
    • Jantová S, Stankovský Š, Špirková K (2004) In vitro antibacterial activity of ten series of substituted quinazolines. Biologia Bratislava 59:741-752
    • (2004) Biologia Bratislava , vol.59 , pp. 741-752
    • Jantová, S.1    Stankovský, Š.2    Špirková, K.3
  • 13
    • 84882763056 scopus 로고    scopus 로고
    • Synthesis of novel 2-aryl-2,3-dihydronaphtho[ 2,1-b]furo[3,2-b]pyridin- 4(1H)-ones of biological importance
    • Nagaraja GK, Prakash GK, Satyanarayan ND, Vaidya VP, Mahadevan KM (2006) Synthesis of novel 2-aryl-2,3-dihydronaphtho[ 2,1-b]furo[3,2-b]pyridin-4(1H)- ones of biological importance. Arkivoc XV:142-152
    • (2006) Arkivoc , vol.15 , pp. 142-152
    • Nagaraja, G.K.1    Prakash, G.K.2    Satyanarayan, N.D.3    Vaidya, V.P.4    Mahadevan, K.M.5
  • 15
    • 0011723947 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. II. Optimization of the phenylpiperazine moiety of 1-[5-Methyl-1-(2- Pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes
    • DOI 10.1248/cpb.50.453
    • Naito H, Ohsuki S, Sugimori M, Atsumi R, Minami M, Nakamura Y, Ishii M, Hirotani K, Kumazawa E, Ejima A (2002) Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. II. Optimization of the phenylpiperazine moiety of 1-[5-methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3- phenylpiperazinyl-1- trans-propenes. Chem Pharm Bull Jpn 50: 453-462. doi:10.1248/cpb.50.453 (Pubitemid 41694955)
    • (2002) Chemical and Pharmaceutical Bulletin , vol.50 , Issue.4 , pp. 453-462
    • Naito, H.1    Ohsuki, S.2    Sugimori, M.3    Atsumi, R.4    Minami, M.5    Nakamura, Y.6    Ishii, M.7    Hirotani, K.8    Kumazawa, E.9    Ejima, A.10
  • 16
    • 34248399597 scopus 로고    scopus 로고
    • Synthesis of novel 2-pyridyl-substituted 2,5-dihydro-2-imino- and 2-aminofuran derivatives via a three component condensation of alkyl isocyanides and acetylenic esters with di-(2-pyridyl) ketone or 2- pyridinecarboxaldehyde
    • Hazeri N, Maghsoodlou MT, Habibi-Khorassani SM, Marandi G, Khandan-Barani K, Ziyaadini M, Aminkhani A (2007) Synthesis of novel 2-pyridyl-substituted 2,5-dihydro-2-imino- and 2-aminofuran derivatives via a three component condensation of alkyl isocyanides and acetylenic esters with di-(2-pyridyl) ketone or 2- pyridinecarboxaldehyde. Arkivoc I:173-181
    • (2007) Arkivoc , vol.1 , pp. 173-181
    • Hazeri, N.1    Maghsoodlou, M.T.2    Habibi-Khorassani, S.M.3    Marandi, G.4    Khandan-Barani, K.5    Ziyaadini, M.6    Aminkhani, A.7
  • 17
    • 56049119881 scopus 로고    scopus 로고
    • Synthesis of 3-hydroxy-2H-iminolactones and 3-hydroxy- 2H-pyrrol 2-ones from reaction between isocyanides and methyl 2-acetylacetonate
    • Hazeri N, Maghsoodlou MT, Habibi-Khorassani SM, Marandi G (2008) Synthesis of 3-hydroxy-2H-iminolactones and 3-hydroxy- 2H-pyrrol 2-ones from reaction between isocyanides and methyl 2-acetylacetonate. Arkivoc XIV:282-288
    • (2008) Arkivoc , vol.14 , pp. 282-288
    • Hazeri, N.1    Maghsoodlou, M.T.2    Habibi-Khorassani, S.M.3    Marandi, G.4
  • 18
    • 38949175026 scopus 로고    scopus 로고
    • Stereoselective synthesis of helical dihydrodipyrrolophenanthroline and hindrance Hexa tert-butyl carboxylatodipyrrolophenanthroline from reaction between 1,10-phenanthroline and dialkyl acetylenedicarboxylates
    • Maghsoodlou MT, Habibi-Khorassani SM, Saghatforoush L, Maghfuri F, Marandi G, Kabiri R (2008) Stereoselective synthesis of helical dihydrodipyrrolophenanthroline and hindrance hexa tertbutyl carboxylatodipyrrolophenanthroline from reaction between 1,10-phenanthroline and dialkyl acetylenedicarboxylates. J Heterocycl Chem 45:289-293. doi:10.1002/jhet.5570450136 (Pubitemid 351231392)
    • (2008) Journal of Heterocyclic Chemistry , vol.45 , Issue.1 , pp. 289-293
    • Maghsoodlou, M.T.1    Khorassani, S.M.H.2    Saghatforoush, L.3    Maghfuri, F.4    Marandi, G.5    Kabiri, R.6
  • 19
    • 34047113810 scopus 로고    scopus 로고
    • A facile synthesis of oxazolo[3,2-a][1,10]phenanthrolines via a new multicomponent reaction
    • doi:10.1016/j.tetlet.2007.03.048
    • Maghsoodlou MT, Marandi G, Hazeri N, Aminkhani A, Kabiri R (2007) A facile synthesis of oxazolo[3,2-a][1,10]phenanthrolines via a new multicomponent reaction. Tetrahedron Lett 48:3197-3199. doi:10.1016/j.tetlet.2007.03.048
    • (2007) Tetrahedron Lett , vol.48 , pp. 3197-3199
    • Maghsoodlou, M.T.1    Marandi, G.2    Hazeri, N.3    Aminkhani, A.4    Kabiri, R.5
  • 20
    • 37049024700 scopus 로고    scopus 로고
    • Green diastereoselective synthesis of highly functionalized trifluoromethylated γ -lactone phosphonate esters bearing a thioester or ketothiophene
    • doi:10.1016/j.tetlet.2007.11.046
    • Rostami-Charati F, Maghsoodlou MT, Habibi-Khorassani SM, Makha M (2008) Green diastereoselective synthesis of highly functionalized trifluoromethylated γ -lactone phosphonate esters bearing a thioester or ketothiophene. Tetrahedron Lett 49:343-347. doi:10.1016/j.tetlet.2007.11.046
    • (2008) Tetrahedron Lett , vol.49 , pp. 343-347
    • Rostami-Charati, F.1    Maghsoodlou, M.T.2    Habibi-Khorassani, S.M.3    Makha, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.