Very low birth weight infants qualifying for a ‘late’ erythrocyte transfusion: Does giving darbepoetin along with the transfusion counteract the transfusion's erythropoietic suppression?

Journal of Perinatology

Volumn 31, Issue , 2011, Pages S17-S21

  Warwood, T L ^a,b,c   Lambert, D K ^a,b,c   Henry, E ^a,b,c   Christensen, R D ^a,b,c  

^a INTERMOUNTAIN HEALTHCARE   (United States)

^b McKay Dee Hospital Center   (United States)

^c Institute for Healthcare Delivery Research   (United States)

Author keywords

Darbepoetin; Hemoglobin; Rbc; Reticulocyte; Transfusion; Vlbw

Indexed keywords

ARNESP; HEMOGLOBIN; LACTIC ACID; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE TRANSFUSION; FEMALE; HEMATOCRIT; HUMAN; LACTATE BLOOD LEVEL; MALE; NEWBORN; PILOT STUDY; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; RETICULOCYTE COUNT; RETICULOCYTOSIS; SINGLE DRUG DOSE; VERY LOW BIRTH WEIGHT;

ANEMIA, NEONATAL; ERYTHROCYTE TRANSFUSION; ERYTHROPOIESIS; ERYTHROPOIETIN; HUMANS; INFANT, NEWBORN; INFANT, VERY LOW BIRTH WEIGHT; INJECTIONS, SUBCUTANEOUS; RETICULOCYTE COUNT;

EID: 79953310176     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/jp.2010.165     Document Type: Article

References (29)

1. Luban NLC. Transfusion of blood and blood products. In: MacDonald and Ramasethu (eds). Atlas of Procedures in Neonatology, 4th edn. Lippincott/Williams and Wilkins: Philadelphia, 2007, pp 317-328.
2. New HV, Stanworth SJ, Engelfriet CP, Reesink HW, McQuilten ZK, Savoia HF et al. Neonatal transfusions. Vox Sang 2009; 96: 62-85.
3. Strauss RG. How I transfuse red blood cells and platelets to infants with the anemia and thrombocytopenia of prematurity. Transfusion 2008; 48: 209-217.
4. Murray NA, Roberts IAG. Neonatal transfusion practice. Arch Dis Child Fetal Neonatal Ed 2004; 89: 101-107.
5. Dodd R, Kurt Roth W, Ashford P, Dax EM, Vyas G. Transfusion medicine and safety. Biologicals 2009; 37: 62-70.
6. Stainsby D, Faber J-C, Jorgensen J. Overview of hemovigilance. In: Simon TL, Soleihm BG, Strauss RG, Snyder EL, Petrides M (eds). Rossi's Principles of Transfusion Medicine, 4th edn. Wiley-Blackwell: Bethesda, MD, 2009, pp 683-698.
7. Millard DD, Gidding SS, Socol ML, MacGregor SN, Dooley SL, Ney JA et al. Effects of intravascular, intrauterine transfusion on prenatal and postnatal hemolysis and erythropoiesis in severe fetal isoimmunization. Pediatrics 1990; 117: 447-454.
8. Wulff H, Wichmann HE, Pantel K, Loeffler M. A mathematical model of erythropoiesis in mice and rats. Part 3: Suppressed erythropoiesis. Cell Tissue Kinet 1989; 22: 51-61.
9. Wiktor-Jedrzejczak W. Erythropoietic stimulation enhances, and erythropoietic inhibition suppresses, multidirectional differentiation in 4-day transient endogenous spleen colonies. Experientia 1981; 37: 1024-1026.
10. Jelkmann W. Effects of erythropoietin on brain function. Curr Pharm Biotechnol 2005; 6: 65-79.
11. McPherson RJ, Juul SE. Erythropoietin for infants with hypoxic-ischemic encephalopathy. Curr Opin Pediatr 2010; 22: 139-145.
12. Bierer R, Peceny MC, Hartenberger CH, Ohls RK. Erythropoietin concentrations and neurodevelopmental outcome in preterm infants. Pediatrics 2006; 118: e635-e640.
13. Testa U. Erythropoietic stimulating agents. Exopert Opin Emerg Drugs 2010; 15: 119-138.
14. Song S, Long SR, Marder WE, Sullivan SD, Kallich J. The impact of methodological approach on cost findings in comparison of epoetin alfa with darbepoetin alfa. Ann Pharmacother 2009; 43: 1203-1210.
15. Warwood TL, Ohls RK, Lambert DK, Jones C, Scoffield SH, Gupta N et al. Intravenous administration of darbepoetin to NICU patients. J Perinatol 2006; 26: 296-300.
16. Warwood TL, Ohls RK, Lambert DK, Leve EA, Veng-Pedersen P, Christensen RD. Urinary excretion of darbepoetin after intravenous vs. subcutaneous administration to preterm neonates. J Perinatol 2006; 26: 636-639.
17. Warwood TL, Ohls RD, Wiedmeier SE, Lambert DK, Jones C, Scoffield SH et al. Singledose darbepoetin administration to anemic preterm neonates. J Perinatol 2008; 25: 725-730.
18. Freise JK, Widness JA, Veng-Pedersen P. Erythropoietic response to endogenous erythropoietin in premature very low birth weight infants. J Pharmacol Exp Ther 2010; 332: 229-237.
19. Baer VL, Lambert DK, Schmutz N, Henry E, Stoddard RA, Miner C et al. Adherence to NICU transfusion guidelines: data from a multihospital healthcare system. J Perinatol 2008; 28: 492-497.
20. Widness JA. Treatment and prevention of neonatal anemia. Neoreviews 2008; 9: 526-533.
21. Crowley M, Kirpalani H. A rational approach to red blood cell transfusion in the neonatal ICU. Curr Opin Pediatr 2010; 22: 151-157.
22. Strauss RG. Data-driven blood banking practices for neonatal RBC transfusions. Transfusion 2000; 40: 1528-1540.
23. Litty CA. Neonatal red cell transfusions. Immunohematology 2008; 24: 10-14.
24. Valieva OA, Thomas P, Mayock DE, Juul SE. Effects of transfusions in extremely low birth weight infants: a retrospective study. J Pediatr 2009; 155: 331-337.
25. Sanchez R, Toy P. Transfusion related acute lung injury: a pediatric perspective. Pediatr Blood Cancer 2005; 45: 248-255.
26. Christensen RD, Lambert DK, Henry E, Wiedmeier SE, Snow GL, Baer VL, et al. Is 'transfusion-associated necrotizing enterocolitis' an authentic pathogenic entity? Transfusion 2010; 50: 1106-1112.
27. Rühl H, Bein G, Sachs UJ. Transfusion-associated graft-versus-host disease. Transfus Med Rev 2009; 23: 62-71.
28. Wardrop CAJ, Holland BM, Veale KEA, Jones JG, Gray OP. Nonphysiological anemia of prematurity. Arch Dis Child 1978; 53: 855-860.
29. Stockman III JA, Garcia JF, Oski FA. The anemia of prematurity. Factors governing the erythropoietin response. N Engl J Med 1977; 296: 647-650.