Elevated estrogen receptor expression in hypothalamic preoptic area decreased by electroacupuncture in ovariectomized rats

Neuroscience Letters

Volumn 494, Issue 2, 2011, Pages 109-113

  Ma, Shulan ^a   Wu, Jihong ^b   Feng, Yi ^a   Chen, Boying ^a  

^a FUDAN UNIVERSITY   (China)

^b EYE AND ENT HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

Electroacupuncture; Estrogen receptors; Hypothalamic preoptic area; Ovariectomized rats

Indexed keywords

BRAIN PROTEIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GONADORELIN; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ELECTROACUPUNCTURE; ESTRADIOL BLOOD LEVEL; FEMALE; GENE EXPRESSION; GONADORELIN RELEASE; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; NEGATIVE FEEDBACK; NONHUMAN; OVARIECTOMY; PREOPTIC AREA; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THERAPY EFFECT; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; ELECTROACUPUNCTURE; FEMALE; GENE EXPRESSION; OVARIECTOMY; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79953284297     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.02.070     Document Type: Article

References (26)

1. Butler J.A., Sjoberg M., Coen C.W. Evidence for oestrogen receptor alpha-immunoreactivity in gonadotrophin-releasing hormone-expressing neurones. J. Neuroendocrinol. 1999, 11:331-335.
2. Chakraborty T.R., Hof P.R., Ng L., Gore A.C. Stereologic analysis of estrogen receptor alpha (ER alpha) expression in rat hypothalamus and its regulation by aging and estrogen. J. Comp. Neurol. 2003, 466:409-421.
3. Chen B.Y. Acupuncture normalizes dysfunction of hypothalamic-pituitary-ovarian axis. Acupunct. Electrother. Res. 1997, 22:97-108.
4. Chu Z., Andrade J., Shupnik M.A., Moenter S.M. Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: dependence on dose and estrogen receptor subtype. J. Neurosci. 2009, 29:5616-5627.
5. Fu H., He Y., Gao Y., Man Y., Liu W., Hao H. Acupuncture on the endometrial morphology, the serum estradiol and progesterone levels, and the expression of endometrial leukaemia-inhibitor factor and osteopontin in rats. Evid. Based Complement. Alternat. Med. 2011, 2011:606514.
6. Goldsmith P.C., Boggan J.E., Thind K.K. Estrogen and progesterone receptor expression in neuroendocrine and related neurons of the pubertal female monkey hypothalamus. Neuroendocrinology 1997, 65:325-334.
7. Herbison A.E. Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons. Endocr. Rev. 1998, 19:302-330.
8. Hrabovszky E., Steinhauser A., Barabas K., Shughrue P.J., Petersen S.L., Merchenthaler I., Liposits Z. Estrogen receptor-beta immunoreactivity in luteinizing hormone-releasing hormone neurons of the rat brain. Endocrinology 2001, 142:3261-3264.
9. Hu L., Gustofson R.L., Feng H., Leung P.K., Mores N., Krsmanovic L.Z., Catt K.J. Converse regulatory functions of estrogen receptor- alpha and-beta subtypes expressed in hypothalamic gonadotropin-releasing hormone neurons. Mol. Endocrinol. 2008, 22:2250-2259.
10. King J.C., Tobet S.A., Snavely F.L., Arimura A.A. LHRH immunopositive cells and their projections to the median eminence and organum vasculosum of the lamina terminalis. J. Comp. Neurol. 1982, 209:287-300.
11. Langub M.C., Watson R.E. Estrogen receptor-immunoreactive glia, endothelia, and ependyma in guinea pig preoptic area and median eminence: electron microscopy. Endocrinology 1992, 130:364-372.
12. Legan S.J., Coon G.A., Karsch F.J. Role of estrogen as initiator of daily LH surges in the ovariectomized rat. Endocrinology 1975, 96:50-56.
13. Li G., Yu J. Research on Acupuncture Treatment of Female Climacteric Syndrome. Shanghai J. Acupunct. Moxib. 2002, 21:6-8.
14. Osterlund M., Kuiper G.G., Gustafsson J.A., Hurd Y.L. Differential distribution and regulation of estrogen receptor- alpha and-beta mRNA within the female rat brain. Brain Res. Mol. Brain Res. 1998, 54:175-180.
15. Park J., Linde K., Manheimer E., Molsberger A., Sherman K., Smith C., Sung J., Vickers A., Schnyer R. The status and future of acupuncture clinical research. J. Altern. Complement. Med. 2008, 14:871-881.
16. Paxinos G., Watson C. The rat brain in stereotaxic coordinates 2005, Elsevier Academic Press. 5th ed.
17. Pfaff D., Keiner M. Atlas of estradiol-concentrating cells in the central nervous system of the female rat. J. Comp. Neurol. 1973, 151:121-158.
18. Roy D., Angelini N.L., Belsham D.D. Estrogen directly respresses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-alpha (ERalpha)- and ERbeta-expressing GT1-7 GnRH neurons. Endocrinology 1999, 140:5045-5053.
19. Sarkar D.K., Fink G. Luteinizing hormone releasing factor in pituitary stalk plasma from long-term ovariectomized rats: effects of steroids. J. Endocrinol. 1980, 86:511-524.
20. Skynner M.J., Sim J.A., Herbison A.E. Detection of estrogen receptor alpha and beta messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons. Endocrinology 1999, 140:5195-5201.
21. Stener-Victorin E., Wikland M., Waldenstrom U., Lundeberg T. Alternative treatments in reproductive medicine: much ado about nothing. Acupuncture-a method of treatment in reproductive medicine: lack of evidence of an effect does not equal evidence of the lack of an effect. Hum. Reprod. 2002, 17:1942-1946.
22. Stener-Victorin E., Wu X. Effects and mechanisms of acupuncture in the reproductive system. Auton. Neurosci. 2010.
23. Witkin J.W., Paden C.M., Silverman A.J. The luteinizing hormone-releasing hormone (LHRH) systems in the rat brain. Neuroendocrinology 1982, 35:429-438.
24. Zhao H., Tian Z.Z., Cheng L.N., Chen B.Y. Electroacupuncture enhances extragonadal aromatization in ovariectomized rats. Reprod. Biol. Endocrinol. 2004, 2:18.
25. Zhao H., Tian Z.Z., Chen B.Y. An important role of corticotropin-releasing hormone in electroacupuncture normalizing the subnormal function of hypothalamus-pituitary-ovary axis in ovariectomized rats. Neurosci. Lett. 2003, 349:25-28.
26. Zhao H., Tian Z.Z., Chen B.Y. Electroacupuncture stimulates hypothalamic aromatization. Brain Res. 2005, 1037:164-170.