Trends over time of virological and immunological characteristics in the Swiss HIV Cohort Study

HIV Medicine

Volumn 12, Issue 5, 2011, Pages 279-288

  Ledergerber, B ^a   Cavassini, M ^b   Battegay, M ^c   Bernasconi, E ^d   Vernazza, P ^e   Hirschel, B ^f   Furrer, H ^g   Rickenbach, M ^b   Weber, R ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

^d Cantonal Hospital Group   (Switzerland)

^e CANTONAL HOSPITAL ST GALLEN   (Switzerland)

^f UNIVERSITY HOSPITAL   (Switzerland)

^g UNIVERSITY OF BERN   (Switzerland)

Author keywords

Antiretroviral therapy; Cohort study; Effectiveness; Time trends

Indexed keywords

VIRUS RNA;

ADULT; AGE; ANTIVIRAL THERAPY; ARTICLE; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; ETHNICITY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SEX; SWITZERLAND; VIRUS INHIBITION; VIRUS LOAD; VIRUS SUPPRESSION;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTI-RETROVIRAL AGENTS; CD4 LYMPHOCYTE COUNT; CD4-CD8 RATIO; COHORT STUDIES; DRUG THERAPY, COMBINATION; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; PATIENT COMPLIANCE; SWITZERLAND; VIRAL LOAD;

EID: 79953284045     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2010.00880.x     Document Type: Article

References (17)

1. Egger M, Hirschel B, Francioli P et al. Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study. Swiss HIV Cohort Study. BMJ 1997; 315: 1194-1199.
2. Palella FJ Jr., Delaney KM, Moorman AC et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998; 338: 853-860.
3. Ledergerber B, Egger M, Opravil M et al. Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Swiss HIV Cohort Study. Lancet 1999; 353: 863-868.
4. Fletcher CV. Translating efficacy into effectiveness in antiretroviral therapy: beyond the pill count. Drugs 2007; 67: 1969-1979.
5. Giordano TP, Suarez-Almazor ME, Grimes RM. The population effectiveness of highly active antiretroviral therapy: are good drugs good enough? Curr HIV/AIDS Rep 2005; 2: 177-183.
6. Giordano TP, Gifford AL, White AC Jr. et al. Retention in care: a challenge to survival with HIV infection. Clin Infect Dis 2007; 44: 1493-1499.
7. von Wyl V, Yerly S, Burgisser P et al. Long-term trends of HIV type 1 drug resistance prevalence among antiretroviral treatment-experienced patients in Switzerland. Clin Infect Dis 2009; 48: 979-987.
8. Ledergerber B, von Overbeck J, Egger M, Luthy R. The Swiss HIV Cohort Study: rationale, organization and selected baseline characteristics. Soz Praventivmed 1994; 39: 387-394.
9. The Swiss HIV Cohort Study.Cohort Profile: the Swiss HIV Cohort Study. Int J Epidemiol 2010; 39: 1179-1189.
10. Glass TR, De Geest S, Weber R et al. Correlates of self-reported nonadherence to antiretroviral therapy in HIV-infected patients: the Swiss HIV Cohort Study. J Acquir Immune Defic Syndr 2006; 41: 385-392.
11. Lampe FC, Gatell JM, Staszewski S et al. Changes over time in risk of initial virological failure of combination antiretroviral therapy: a multicohort analysis, 1996 to 2002. Arch Intern Med 2006; 166: 521-528.
12. Kitahata MM, Koepsell TD, Deyo RA, Maxwell CL, Dodge WT, Wagner EH. Physicians' experience with the acquired immunodeficiency syndrome as a factor in patients' survival. N Engl J Med 1996; 334: 701-706.
13. Kitahata MM, Van Rompaey SE, Shields AW. Physician experience in the care of HIV-infected persons is associated with earlier adoption of new antiretroviral therapy. J Acquir Immune Defic Syndr 2000; 24: 106-114.
14. Delgado J, Heath KV, Yip B et al. Highly active antiretroviral therapy: physician experience and enhanced adherence to prescription refill. Antivir Ther 2003; 8: 471-478.
15. Herek GM, Capitanio JP, Widaman KF. HIV-related stigma and knowledge in the United States: prevalence and trends, 1991-1999. Am J Public Health 2002; 92: 371-377.
16. Wood E, Kerr T, Marshall BD et al. Longitudinal community plasma HIV-1 RNA concentrations and incidence of HIV-1 among injecting drug users: prospective cohort study. BMJ 2009; 338: b1649.
17. Granich RM, Gilks CF, Dye C, De Cock KM, Williams BG. Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model. Lancet 2009; 373: 48-57.