Acute oral toxicity in mice of a new palytoxin analog: 42-Hydroxy-palytoxin

Toxicon

Volumn 57, Issue 5, 2011, Pages 755-763

  Tubaro, A ^a   Del Favero, G ^a   Beltramo, D ^b   Ardizzone, M ^b   Forino, M ^c   De Bortoli, M ^a   Pelin, M ^a   Poli, M ^d   Bignami, G ^e   Ciminiello, P ^c   Sosa, S ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b Istituto di Ricerche Biomediche Antoine Marxer SpA   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^e PanThera Biopharma LLC   (United States)

Author keywords

42 Hydroxy palytoxin (42 OH PLTX); Acute oral toxicity; Algal toxins; Light microscopy; Mice

Indexed keywords

42 HYDROXYPALYTOXIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; LACTATE DEHYDROGENASE; PALYTOXIN; POTASSIUM ION; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME BLOOD LEVEL; FEMALE; HEART MUSCLE; HEMOLYSIS; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LD 50; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; SURVIVAL TIME; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; CNIDARIAN VENOMS; FEMALE; HEMOLYSIS; HISTOLOGICAL TECHNIQUES; LETHAL DOSE 50; MASS SPECTROMETRY; MICE; PYRANS; STOMACH;

ALGAE; MUS;

EID: 79953270245     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2011.02.009     Document Type: Article

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