Long-term effects of metformin and lifestyle modification on nonalcoholic fatty liver disease obese adolescents

Journal of Obesity

Volumn 2010, Issue , 2010, Pages

  Tock, Lian ^a   Dâmaso, Ana R ^a   De Piano, Aline ^a   Carnier, June ^a   Sanches, Priscila L ^a   Lederman, Henrique Manoel ^a   Ernandes, Regina M Y ^a   De Mello, Marco Túlio ^a   Tufik, Sérgio ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79953254022     PISSN: 20900708     EISSN: 20900716     Source Type: Journal    
DOI: 10.1155/2010/831901     Document Type: Article

References (30)

1. Machado M., Cortez-Pinto H., Non-alcoholic fatty liver disease and insulin resistance. European Journal of Gastroenterology and Hepatology 2005 17 8 823 826 10.1097/00042737-200508000-00008 2-s2.0-23044503205 (Pubitemid 41073319)
2. Tock L., Prado W. L., Caranti D. A., Nonalcoholic fatty liver disease decrease in obese adolescents after multidisciplinary therapy. European Journal of Gastroenterology and Hepatology 2006 18 12 1241 1245 10.1097/01.meg. 0000243872.86949.95 2-s2.0-33750945522 (Pubitemid 44737053)
3. Bugianesi E., Gentilcore E., Manini R., A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease. American Journal of Gastroenterology 2005 100 5 1082 1090 10.1111/j.1572-0241.2005.41583.x 2-s2.0-19144365586 (Pubitemid 40769045)
4. Dâmaso A. R., do Prado W. L., de Piano A., Relationship between nonalcoholic fatty liver disease prevalence and visceral fat in obese adolescents. Digestive and Liver Disease 2008 40 2 132 139 10.1016/j.dld.2007. 09.009 2-s2.0-38049010038
5. van der Poorten D., Milner K.-L., Hui J., Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology 2008 48 2 449 457 10.1002/hep.22350 2-s2.0-49649096375
6. Chavez-Tapia N. C., Sanchez-Avila F., Vasquez-Fernandez F., Torres-Machorro A., Tellez-Avila F. I., Uribe M., Non-alcoholic fatty-liver disease in pediatric populations. Journal of Pediatric Endocrinology and Metabolism 2007 20 10 1059 1073 2-s2.0-36349024435 (Pubitemid 350148455)
7. Freemark M., Liver dysfunction in paediatric obesity: a randomized, controlled trial of metformin. Acta Paediatrica 2007 96 9 1326 1332 10.1111/j.1651-2227.2007.00429.x 2-s2.0-34548135209 (Pubitemid 47300703)
8. Zuhri-Yafi M. I., Brosnan P. G., Hardin D. S., Treatment of type 2 diabetes mellitus in children and adolescents. Journal of Pediatric Endocrinology and Metabolism 2002 15 supplement 1 541 546 2-s2.0-0036012948 (Pubitemid 34704764)
9. Freemark M., Bursey D., The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes. Pediatrics 2001 107 4 E55 E60 2-s2.0-0035321014
10. Lustig R. H., Mietus-Snyder M. L., Bacchetti P., Lazar A. A., Velasquez-Mieyer P. A., Christensen M. L., Insulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese children. Journal of Pediatrics 2006 148 1 23 29 10.1016/j.jpeds.2005.08.075 2-s2.0-30744443527 (Pubitemid 43098951)
11. Burgert T. S., Duran E. J., Goldberg-Gell R., Short-term metabolic and cardiovascular effects of metformin in markedly obese adolescents with normal glucose tolerance. Pediatric Diabetes 2008 9 6 567 576 10.1111/j.1399-5448.2008. 00434.x 2-s2.0-56649107790
12. Centers for Disease Control and Prevention,. National Center for Health Statistics. CDC growth charts: United States, May 2000, http://www.cdc.gov/ growthcharts/
13. Tanner J. M., Whitehouse R. H., Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Archives of Disease in Childhood 1976 51 3 170 179
14. Schwimmer J. B., Deutsch R., Rauch J. B., Behling C., Newbury R., Lavine J. E., Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease. Journal of Pediatrics 2003 143 4 500 505 10.1067/S0022-3476(03)00325-1 2-s2.0-0242361733 (Pubitemid 37352510)
15. WHO (World Health Organization), Obesity: preventing and managing the global epidemic. Report of a WHO Consultation 2004 Geneva, Switzerland World Health Organization
16. Ribeiro-Filho F. F., Faria A. N., Azjen S., Zanella M.-T., Ferreira S. R. G., Methods of estimation of visceral fat: advantages of ultrasonography. Obesity Research 2003 11 12 1488 1494 2-s2.0-2142797515 (Pubitemid 41127333)
17. Saadeh S., Younossi Z. M., Remer E. M., The utility of radiological imaging in nonalcoholic fatty liver disease. Gastroenterology 2002 123 3 745 750 10.1053/gast.2002.35354 2-s2.0-0036729447 (Pubitemid 34977081)
18. NRC, Dietary Reference Intake: Applications in Dietary Assessment 2001 Washington, DC, USA National Academic Press
19. de Piano A., Prado W. L., Caranti D. A., Metabolic and nutritional profile of obese adolescents with nonalcoholic fatty liver disease. Journal of Pediatric Gastroenterology and Nutrition 2007 44 4 446 452 10.1097/MPG. 0b013e31803815d9 2-s2.0-34147187336 (Pubitemid 46573227)
20. ACSM position stand on the appropriate intervention strategies for weight loss and prevention of weight regain for adults. Medicine & Science in Sports & Exercise 2001 33 12 2145 2156
21. Alba L. M., Lindor K., Review article: non-alcoholic fatty liver disease. Alimentary Pharmacology and Therapeutics 2003 17 8 977 986 10.1046/j.1365-2036. 2003.01493.x 2-s2.0-0038707252 (Pubitemid 36560797)
22. Park J.-W., Jeong G., Kim S. J., Kim M. K., Park S. M., Predictors reflecting the pathological severity of non-alcoholic fatty liver disease: comprehensive study of clinical and immunohistochemical findings in younger Asian patients. Journal of Gastroenterology and Hepatology 2007 22 4 491 497 10.1111/j.1440-1746.2006.04758.x 2-s2.0-33947261669 (Pubitemid 46434984)
23. Nobili V., Marcellini M., Devito R., NAFLD in children: a prospective clinical-pathological study and effect of lifestyle advice. Hepatology 2006 44 2 458 465 10.1002/hep.21262 2-s2.0-33747077203 (Pubitemid 44214885)
24. Fu J.-F., Liang L., Zou C.-C., Prevalence of the metabolic syndrome in Zhejiang Chinese obese children and adolescents and the effect of metformin combined with lifestyle intervention. International Journal of Obesity 2007 31 1 15 22 10.1038/sj.ijo.0803453 2-s2.0-33845809235 (Pubitemid 46006010)
25. Hundal R. S., Inzucchi S. E., Metformin: new understandings, new uses. Drugs 2003 63 18 1879 1894 10.2165/00003495-200363180-00001 (Pubitemid 37108399)
26. Orchard T. J., Temprosa M., Goldberg R., The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the diabetes prevention program randomized trial. Annals of Internal Medicine 2005 142 8 611 619 2-s2.0-17144389303 (Pubitemid 40529957)
27. Utzschneider K. M., Kahn S. E., The role of insulin resistance in non-alcoholic fatty liver disease. Journal of Clinical Endocrinology & Metabolism 2006 91 4753 4761 (Pubitemid 44917301)
28. Rodrigues A. N., Perez A. J., Pires J. G. P., Cardiovascular risk factors, their associations and presence of metabolic syndrome in adolescents. Jornal de Pediatria 2009 85 1 55 60 10.2223/JPED.1867 2-s2.0-60149085086
29. Uygun A., Kadayifci A., Isik A. T., Metformin in the treatment of patients with non-alcoholic steatohepatitis. Alimentary Pharmacology and Therapeutics 2004 19 5 537 544 10.1111/j.1365-2036.2004.01888.x 2-s2.0-1642296465 (Pubitemid 38387180)
30. Nadeau K. J., Ehlers L. B., Zeitler P. S., Love-Osborne K., Treatment of non-alcoholic fatty liver disease with metformin versus lifestyle intervention in insulin-resistant adolescents. Pediatric Diabetes 2009 10 1 5 13 10.1111/j.1399-5448.2008.00450.x