Poly(HEMA-Zidovudine) conjugate: A macromolecular pro-drug for improvement in the biopharmaceutical properties of the drug

Drug Delivery

Volumn 18, Issue 4, 2011, Pages 272-280

  Neeraj, Agrawal ^a   Chandrasekar, M J N ^b   Sara, U V S ^c   Rohini, A ^a  

^a Pacific College of Pharmacy   (India)

^b JSS COLLEGE OF PHARMACY   (India)

^c DJ College of Pharmacy   (India)

Author keywords

5 O succinylzidovudine; AIDS; polymeric pro drug; succinic spacer; sustained release

Indexed keywords

CHYMOTRYPSIN A; MONOMER; PEPSIN A; POLY(HEMA ZIDOVUDINE); PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; INTESTINE FLUID; NONHUMAN; PRIORITY JOURNAL; STOMACH JUICE; SUSTAINED DRUG RELEASE;

ANIMALS; ANTI-HIV AGENTS; BIOLOGICAL AVAILABILITY; DELAYED-ACTION PREPARATIONS; HALF-LIFE; HYDROGEN-ION CONCENTRATION; MACROMOLECULAR SUBSTANCES; MALE; METHACRYLATES; POLYMERIZATION; PRODRUGS; RABBITS; ZIDOVUDINE;

EID: 79953238573     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2010.536272     Document Type: Article

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