메뉴 건너뛰기




Volumn 12, Issue 3, 2011, Pages 365-377

Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample

Author keywords

5 HTR1B; ABCB1; antidepressant; depression; FKBP5; suicidal ideation

Indexed keywords

CATECHOL METHYLTRANSFERASE; CLOMIPRAMINE; CYTOCHROME P450 2D6; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 5; LIOTHYRONINE; LITHIUM; MULTIDRUG RESISTANCE PROTEIN 1; NEFAZODONE; PAROXETINE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 1; TRYPTOPHAN HYDROXYLASE 2; UNCLASSIFIED DRUG; VENLAFAXINE;

EID: 79953234522     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.10.189     Document Type: Article
Times cited : (53)

References (55)
  • 1
    • 70449726771 scopus 로고    scopus 로고
    • Suicidal ideation during treatment of depression with esckalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): A clinical trial
    • Perroud N, Uher R, Marusic A et al.: Suicidal ideation during treatment of depression with esckalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial. BMC Med. 7, 60 (2009).
    • (2009) BMC Med. , vol.7 , pp. 60
    • Perroud, N.1    Uher, R.2    Marusic, A.3
  • 2
    • 67650093741 scopus 로고    scopus 로고
    • Clinical correlates of the worsening or emergence of suicidal ideation during SSRI treatment of depression: An examination of citalopram in the STAR*D study
    • Zisook S, Trivedi MH, Warden D et al.: Clinical correlates of the worsening or emergence of suicidal ideation during SSRI treatment of depression: an examination of citalopram in the STAR*D study. Affect. Disord. 117(1-2), 63-73 (2009).
    • (2009) Affect. Disord. , vol.117 , Issue.1-2 , pp. 63-73
    • Zisook, S.1    Trivedi, M.H.2    Warden, D.3
  • 5
    • 71649102804 scopus 로고    scopus 로고
    • Clinical features of patients with treatment-emergent suicidal behavior following initiation of paroxetine therapy
    • Kraus JE, Horrigan JP, Carpenter DJ, Fong R, Barrett PS, Davies JT: Clinical features of patients with treatment-emergent suicidal behavior following initiation of paroxetine therapy. Affect. Disord. 120(1-3), 40-47 (2010).
    • (2010) Affect. Disord. , vol.120 , Issue.1-3 , pp. 40-47
    • Kraus, J.E.1    Horrigan, J.P.2    Carpenter, D.J.3    Fong, R.4    Barrett, P.S.5    Davies, J.T.6
  • 8
    • 34249943795 scopus 로고    scopus 로고
    • Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study
    • DOI 10.1001/archpsyc.64.6.689
    • Perils RH, Purcell S, FavaM .: Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. Arch. Gen. Psychiatry 64(6), 689-697 (2007). (Pubitemid 46878669)
    • (2007) Archives of General Psychiatry , vol.64 , Issue.6 , pp. 689-697
    • Perlis, R.H.1    Purcell, S.2    Fava, M.3    Fagerness, J.4    Rush, A.J.5    Trivedi, M.H.6    Smoller, J.W.7
  • 9
    • 70350051039 scopus 로고    scopus 로고
    • Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project
    • Perroud N,Aitchison KJ, Uher R, et al: Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project. Neuropsychopharmacology 34(12), 2517-2528 (2009).
    • (2009) Neuropsychopharmacology , vol.34 , Issue.12 , pp. 2517-2528
    • Perroud, N.1    Aitchison, K.J.2    Uher, R.3
  • 10
    • 75749096035 scopus 로고    scopus 로고
    • Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study Am
    • Brent D, Melhem N, Ferrell R, et al.: Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study Am. J. Psychiatry 167(2), 190-197 (2010).
    • (2010) J. Psychiatry , vol.167 , Issue.2 , pp. 190-197
    • Brent, D.1    Melhem, N.2    Ferrell, R.3
  • 11
    • 70249083016 scopus 로고    scopus 로고
    • Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients
    • Laje G, Allen AS, Akula N, Manji H, John Rush A, McMahon FJ: Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients. Pharmacogenet. Genomics 19(9), 666-674 (2009).
    • (2009) Pharmacogenet. Genomics , vol.19 , Issue.9 , pp. 666-674
    • Laje, G.1    Allen, A.S.2    Akula, N.3    Manji, H.4    John Rush, A.5    McMahon, F.J.6
  • 12
    • 84964749750 scopus 로고    scopus 로고
    • Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project
    • Epub ahead of print
    • Perroud N, Uher R, Ng MY et al.: Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project. Pharmacogenomics J. (2010) (Epub ahead of print).
    • (2010) Pharmacogenomics J.
    • Perroud, N.1    Uher, R.2    Ng, M.Y.3
  • 13
    • 33344464148 scopus 로고    scopus 로고
    • A stepwise drug treatment algorithm to obtain complete remission in depression: A Geneva study
    • Bondolfi G,AubryJM, GolazJ, Gex-FabryM, Gervasoni N, Bertschy G: A stepwise drug treatment algorithm to obtain complete remission in depression: a Geneva study. Swiss Med. Wkly 136(5-6), 78-85 (2006). (Pubitemid 43287243)
    • (2006) Swiss Medical Weekly , vol.136 , Issue.5-6 , pp. 78-85
    • Bondolfi, G.1    Aubry, J.M.2    Golaz, J.3    Gex-Fabry, M.4    Gervasoni, N.5    Bertschy, G.6
  • 15
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, Asberg M: A new depression scale designed to be sensitive to change. Br. J. Psychiatry 134, 382-389 (1979). (Pubitemid 9136500)
    • (1979) British Journal of Psychiatry , vol.134 , Issue.4 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 16
    • 0036430260 scopus 로고    scopus 로고
    • Association of anger-related traits with SNPs in the TPH gene
    • DOI 10.1038/sj.mp.4001128
    • Rujescu D, Giegling I, Bondy B, Gietl A, Zill P, Moller HJ: Association of anger-related traits with SNPs in the TPHgene. Mol. Psychiatry 7(9), 1023-1029 (2002). (Pubitemid 35333060)
    • (2002) Molecular Psychiatry , vol.7 , Issue.9 , pp. 1023-1029
    • Rujescu, D.1    Giegling, I.2    Bondy, B.3    Gietl, A.4    Zill, P.5    Moller, H.-J.6
  • 17
    • 0033104318 scopus 로고    scopus 로고
    • Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene
    • DOI 10.1016/S0006-3223(98)00375-8, PII S0006322398003758
    • Manuck SB, Flory JD, Ferrell RE, Dent KM, Mann JJ, Muldoon MF: Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene. Biol. Psychiatry 45(5), 603-614 (1999). (Pubitemid 29147369)
    • (1999) Biological Psychiatry , vol.45 , Issue.5 , pp. 603-614
    • Manuck, S.B.1    Flory, J.D.2    Ferrell, R.E.3    Dent, K.M.4    Mann, J.J.5    Muldoon, M.F.6
  • 18
    • 59149092135 scopus 로고    scopus 로고
    • Modulation of anger control in suicide attempters by TPH-1
    • Baud P, Perroud N, Courtet P et al.: Modulation of anger control in suicide attempters by TPH-1. Genes Brain Behav. 8(1), 97-100 (2009).
    • (2009) Genes Brain Behav. , vol.8 , Issue.1 , pp. 97-100
    • Baud, P.1    Perroud, N.2    Courtet, P.3
  • 21
    • 77949366372 scopus 로고    scopus 로고
    • COMT but not serotonin-related genes modulates the influence of childhood abuse on anger traits
    • Perroud N, Jaussent I, Guillaume S et al.: COMT but not serotonin-related genes modulates the influence of childhood abuse on anger traits. Genes Brain Behav. 9(2), 193-202 (2010).
    • (2010) Genes Brain Behav. , vol.9 , Issue.2 , pp. 193-202
    • Perroud, N.1    Jaussent, I.2    Guillaume, S.3
  • 22
    • 0033512357 scopus 로고    scopus 로고
    • MAO-A and -B gene knock-out mice exhibit distinctly different behavior
    • Shih JC, Chen K: MAO-A and -B gene knock-out mice exhibit distinctly different behavior. Neurobiology (Bp) 7(2), 235-246 (1999). (Pubitemid 30353425)
    • (1999) Neurobiology , vol.7 , Issue.2 , pp. 235-246
    • Shih, J.C.1    Chen, K.2
  • 24
    • 38349022442 scopus 로고    scopus 로고
    • Serotonin receptor genes 5HT1A and 5HT2A modify the relation between childhood temperament and adulthood hostility
    • Keltikangas-Jarvinen L, Puttonen S, Kivimaki M et al.: Serotonin receptor genes 5HT1A and 5HT2A modify the relation between childhood temperament and adulthood hostility. Genes Brain Behav. 7(1), 46-52 (2008).
    • (2008) Genes Brain Behav. , vol.7 , Issue.1 , pp. 46-52
    • Keltikangas-Jarvinen, L.1    Puttonen, S.2    Kivimaki, M.3
  • 28
    • 0038094426 scopus 로고    scopus 로고
    • A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits
    • DOI 10.1016/S0006-3223(02)01831-0
    • Rujescu D, Giegling I, Gietl A, Hartmann AM, Moller HJ: A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits. Biol. Psychiatry 54(1), 34-39(2003). (Pubitemid 36776721)
    • (2003) Biological Psychiatry , vol.54 , Issue.1 , pp. 34-39
    • Rujescu, D.1    Giegling, I.2    Gietl, A.3    Hartmann, A.M.4    Moller, H.-J.5
  • 29
    • 58149124253 scopus 로고    scopus 로고
    • CYP2D6 and ABCBl genetic variability: Influence on paroxetine plasma level and therapeutic response
    • Gex-Fabry M, Eap CB, Oneda B et al. CYP2D6 and ABCBl genetic variability: influence on paroxetine plasma level and therapeutic response. Ther. DrugMonit. 30(4), 474-482 (2008).
    • (2008) Ther. DrugMonit. , vol.30 , Issue.4 , pp. 474-482
    • Gex-Fabry, M.1    Eap, C.B.2    Oneda, B.3
  • 31
    • 62149114432 scopus 로고    scopus 로고
    • Differential efficacy of esckalopram and nortriptyline on dimensional measures of depression
    • Uher R, Maier W, Hauser J et al.: Differential efficacy of esckalopram and nortriptyline on dimensional measures of depression. Br. J. Psychiatry 194(3), 252-259 (2009).
    • (2009) Br. J. Psychiatry , vol.194 , Issue.3 , pp. 252-259
    • Uher, R.1    Maier, W.2    Hauser, J.3
  • 32
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • DOI 10.1038/sj.hdy.6800717, PII 6800717
    • Li J, Ji L: Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity 95(3), 221-227 (2005). (Pubitemid 43093236)
    • (2005) Heredity , vol.95 , Issue.3 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 33
    • 1842539516 scopus 로고    scopus 로고
    • A Simple Correction for Multiple Testing for Single-Nucleotide Polymorphisms in Linkage Disequilibrium with Each Other
    • DOI 10.1086/383251
    • Nyholt DR: A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet. 74(4), 765-769 (2004). (Pubitemid 38420107)
    • (2004) American Journal of Human Genetics , vol.74 , Issue.4 , pp. 765-769
    • Nyholt, D.R.1
  • 34
    • 0037080655 scopus 로고    scopus 로고
    • Sample size requirements for matched case-control studies of gene-environment interaction
    • DOI 10.1002/sim.973
    • Gauderman WJ: Sample size requirements for matched case-control studies of gene-environment interaction. Stat. Med. 21, 35-50 (2002). (Pubitemid 34065703)
    • (2002) Statistics in Medicine , vol.21 , Issue.1 , pp. 35-50
    • Gauderman, W.J.1
  • 36
    • 33846250328 scopus 로고    scopus 로고
    • Suicidalky scores during double-blind fluoxetine and desipramine treatment in Mexican Americans
    • SharmaA, Busnello JV, Ribeiro L et al.: Suicidalky scores during double-blind fluoxetine and desipramine treatment in Mexican Americans. Clin. Psychopharmacol. 27(1), 99-101 (2007).
    • (2007) Clin. Psychopharmacol. , vol.27 , Issue.1 , pp. 99-101
    • Sharma, A.1    Busnello, J.V.2    Ribeiro, L.3
  • 37
    • 19744382704 scopus 로고    scopus 로고
    • Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: Nested case-control study
    • Martinez C, Rietbrock S, Wise L et al.: Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study. BMJ 330(7488), 389 (2005).
    • (2005) BMJ , vol.330 , Issue.7488 , pp. 389
    • Martinez, C.1    Rietbrock, S.2    Wise, L.3
  • 40
    • 0026460459 scopus 로고
    • Akathisia, suicidality, and fluoxetine
    • Hamilton MS, Opler LA: Akathisia, suicidality, and fluoxetine. Clin. Psychiatry 53(11), 401-406 (1992).
    • (1992) Clin. Psychiatry , vol.53 , Issue.11 , pp. 401-406
    • Hamilton, M.S.1    Opler, L.A.2
  • 41
    • 0027402340 scopus 로고
    • Antidepressant drugs and the emergence of suicidal tendencies
    • Teicher MH, Glod CA, Cole JO: Antidepressant drugs and the emergence of suicidal tendencies. DrugSaf 8(3), 186-212 (1993). (Pubitemid 23123065)
    • (1993) Drug Safety , vol.8 , Issue.3 , pp. 186-212
    • Teicher, M.H.1    Glod, C.A.2    Cole, J.O.3
  • 42
    • 0033660431 scopus 로고    scopus 로고
    • Population pharmacokinetics of clomipramine, desmethylclomipramine, and hydroxylated metabolites in patients with depression receiving chronic treatment: Model evaluation
    • Gex-Fabry M, Haffen E, Paintaud G et al.: Population pharmacokinetics of clomipramine, desmethylclomipramine, and hydroxylated metabolites in patients with depression receiving chronic treatment: model evaluation. Ther. DrugMonit. 22(6), 701-711 (2000).
    • (2000) Ther. DrugMonit. , vol.22 , Issue.6 , pp. 701-711
    • Gex-Fabry, M.1    Haffen, E.2    Paintaud, G.3
  • 43
    • 77952288213 scopus 로고    scopus 로고
    • Does early improvement in major depression protect against treatment emergent suicidal ideation?
    • Seemuller F, Schennach-Wolff R, Obermeier M, Henkel V, Moller HJ, Riedel M: Does early improvement in major depression protect against treatment emergent suicidal ideation? Affect. Disord. 124(1-2), 183-186(2010).
    • (2010) Affect. Disord. , vol.124 , Issue.1-2 , pp. 183-186
    • Seemuller, F.1    Schennach-Wolff, R.2    Obermeier, M.3    Henkel, V.4    Moller, H.J.5    Riedel, M.6
  • 44
    • 60549096097 scopus 로고    scopus 로고
    • Family-based association of FKBP5 in bipolar disorder
    • WillourVL, Chen H, Toolan J et al.: Family-based association of FKBP5 in bipolar disorder. Mol. Psychiatry 14(3), 261-268 (2009).
    • (2009) Mol. Psychiatry , vol.14 , Issue.3 , pp. 261-268
    • Willour, V.L.1    Chen, H.2    Toolan, J.3
  • 45
    • 77953611084 scopus 로고    scopus 로고
    • Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide
    • Roy A, Gorodetsky E, Yuan Q, Goldman D, Enoch MA: Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide. Neuropsychopharmacology 35 (8), 1674-1683 (2010).
    • (2010) Neuropsychopharmacology , vol.35 , Issue.8 , pp. 1674-1683
    • Roy, A.1    Gorodetsky, E.2    Yuan, Q.3    Goldman, D.4    Enoch, M.A.5
  • 46
    • 48249091243 scopus 로고    scopus 로고
    • Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
    • IsingM, DeppingAM, SiebertzA et al.: Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls. Eur. J. Neurosci. 28(2), 389-398 (2008).
    • (2008) Eur. J. Neurosci. , vol.28 , Issue.2 , pp. 389-398
    • Ising, M.1    Depping, A.M.2    Siebertz, A.3
  • 48
    • 0035169503 scopus 로고    scopus 로고
    • Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three New World primates
    • DOI 10.1006/gcen.2001.7696
    • Scammell JG, Denny WB, Valentine DL, Smith DF: Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three new world primates. Gen. Comp. Endocrinol. 124(2), 152-165 (2001). (Pubitemid 33065587)
    • (2001) General and Comparative Endocrinology , vol.124 , Issue.2 , pp. 152-165
    • Scammell, J.G.1    Denny, W.B.2    Valentine, D.L.3    Smith, D.F.4
  • 49
    • 33845724030 scopus 로고    scopus 로고
    • A review of prospective studies of biologic predictors of suicidal behavior in mood disorders
    • Mann JJ, Currier D: A review of prospective studies of biologic predictors of suicidal behavior in mood disorders. Arch. Suicide Res. 11(1), 3-16 (2007).
    • (2007) Arch. Suicide Res. , vol.11 , Issue.1 , pp. 3-16
    • Mann, J.J.1    Currier, D.2
  • 51
    • 1642523162 scopus 로고    scopus 로고
    • Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • DOI 10.1016/j.clpt.2003.09.012
    • Marzolini C, Paus E, Buclin T, Kim RB: Polymorphisms in human MDRl (P-glycoprotein): recent advances and clinical relevance. Clin. Pharmacol. Ther. 75(1), 13-33 (2004). (Pubitemid 38130115)
    • (2004) Clinical Pharmacology and Therapeutics , vol.75 , Issue.1 , pp. 13-33
    • Marzolini, C.1    Paus, E.2    Buclin, T.3    Kim, R.B.4
  • 52
    • 34249058785 scopus 로고    scopus 로고
    • ABCB1 genotype and PGP expression, function and therapeutic drug response: A critical review and recommendations for future research
    • DOI 10.1038/sj.tpj.6500413, PII 6500413
    • Leschziner GD, Andrew T, Pirmohamed M, Johnson MR: ABCBl genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research. PharmacogenomicsJ. 7(3), 154-179 (2007). (Pubitemid 46794925)
    • (2007) Pharmacogenomics Journal , vol.7 , Issue.3 , pp. 154-179
    • Leschziner, G.D.1    Andrew, T.2    Pirmohamed, M.3    Johnson, M.R.4
  • 54
    • 0036468373 scopus 로고    scopus 로고
    • Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus
    • DOI 10.1016/S0014-2999(01)01578-3, PII S0014299901015783
    • Gur E, Dremencov E, Van de Kar LD, Lerer B, Newman ME: Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus. Eur. J. Pharmacol. 436(1-2), 57-65 (2002). (Pubitemid 34142398)
    • (2002) European Journal of Pharmacology , vol.436 , Issue.1-2 , pp. 57-65
    • Gur, E.1    Dremencov, E.2    Van De Kar, L.D.3    Lerer, B.4    Newman, M.E.5
  • 55
    • 0033880456 scopus 로고    scopus 로고
    • Chronic clomipramine alters presynaptic 5-HT(1B) and postsynaptic 5-HT(1A) receptor sensitivity in rat hypothalamus and hippocampus, respectively
    • DOI 10.1016/S0028-3908(00)00077-0, PII S0028390800000770
    • Newman ME, Gur E, Dremencov E, Garcia F, Lerer B, Van de Kar LD: Chronic clomipramine alters presynaptic 5-HT(lB) and postsynaptic 5-HT(lA) receptor sensitivity in rat hypothalamus and hippocampus, respectively. Neuropharmacology 39(12), 2309-2317 (2000). (Pubitemid 30642773)
    • (2000) Neuropharmacology , vol.39 , Issue.12 , pp. 2309-2317
    • Newman, M.E.1    Gur, E.2    Dremencov, E.3    Garcia, F.4    Lerer, B.5    Van De Kar, L.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.