Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity

Critical Care Medicine

Volumn 39, Issue 4, 2011, Pages 765-769

  Sun, Quiang ^a   Cai, Jianmei ^b   Zhou, Jiangrui ^a   Tao, Hengyi ^a   Zhang, John H ^c   Zhang, Wei ^b   Sun, Xue Jun ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c LOMA LINDA UNIVERSITY   (United States)

Author keywords

carbon monoxide poisoning; delayed neurologic sequelae; hydrogen; inflammation; myelin basic protein; oxidative stress

Indexed keywords

CALCIUM ION; HYDROGEN RICH SALINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; IONIZED CALCIUM BINDING ADAPTER MOLECULE 1; MYELIN BASIC PROTEIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DISEASE; BRAIN TISSUE; CARBON MONOXIDE INTOXICATION; CELL DEATH; COGNITIVE DEFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENCEPHALITIS; HIPPOCAMPUS; MALE; MAZE TEST; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESUSCITATION;

EID: 79953214007     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318206bf44     Document Type: Article

References (31)

1. Weaver LK: Clinical practice. Carbon monoxide poisoning. N Engl J Med 2009; 360: 1217-1225.
2. Ernst A, Zibrak JD: Carbon monoxide poisoning. N Engl J Med 1998; 339:1603-1608. (Pubitemid 28536136)
3. Weaver LK, Hopkins RO, Chan KJ, et al. Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med 2002; 347: 1057-1067.
4. Thom SR, Bhopale VM, Fisher D, et al. Delayed neuropathology after carbon monoxide poisoning is immune-mediated. Proc Natl Acad Sci USA 2004; 101:13660-13665. (Pubitemid 39238459)
5. Thom SR, Bhopale VM, Han ST, et al. Intravascular neutrophil activation due to carbon monoxide poisoning. Am J Respir Crit Care Med 2006; 174:1239-1248. (Pubitemid 44924825)
6. Han ST, Bhopale VM, Thom SR: Xanthine oxidoreductase and neurological sequelae of carbon monoxide poisoning. Toxicol Lett 2007; 170:111-115. (Pubitemid 46636116)
7. Thom SR, Bhopale VM, Milovanova TM, et al. Plasma biomarkers in carbon monoxide poisoning. Clin Toxicol (Phila) 2010; 48:47-56.
8. Thom SR, Fisher D, Manevich Y: Roles for platelet-activating factor and *NO-derived oxidants causing neutrophil adherence after CO poisoning. Am J Physiol Heart Circ Physiol 2001; 281:H923-H930.
9. Thom SR, Bhopale VM, Fisher D: Hyperbaric oxygen reduces delayed immune-mediated neuropathology in experimental carbon monoxide toxicity. Toxicol Appl Pharmacol 2006; 213:152-159. (Pubitemid 44251057)
10. Buckley NA, Isbister GK, Stokes B, et al. Hyperbaric oxygen for carbon monoxide poisoning: a systematic review and critical analysis of the evidence. Toxicol Rev 2005; 24: 75-92. (Pubitemid 41455879)
11. Stoller KP: Hyperbaric oxygen and carbon monoxide poisoning: A critical review. Neurol Res 2007; 29:146-155. (Pubitemid 46685268)
12. Bitterman H: Bench-to-bedside review: Oxygen as a drug. Crit Care 2009; 13:205.
13. Wood KC, Gladwin MT: The hydrogen highway to reperfusion therapy. Nat Med 2007; 13:673-674. (Pubitemid 46889746)
14. Cai J, Kang Z, Liu WW, et al. Hydrogen therapy reduces apoptosis in neonatal hypoxia- ischemia rat model. Neurosci Lett 2008; 441:167-172.
15. Liu Q, Shen WF, Sun HY, et al. Hydrogenrich saline protects against liver injury in rats with obstructive jaundice. Liver Int 2010; 30:958-968.
16. Sun Q, Kang Z, Cai J, et al. Hydrogen-rich saline protects myocardium against ischemia/ reperfusion injury in rats. Exp Biol Med (Maywood) 2009; 234:1212-1219.
17. Zheng X, Mao Y, Cai J, et al. Hydrogen-rich saline protects against intestinal ischemia/ reperfusion injury in rats. Free Radic Res 2009; 43:478-484.
18. Chen H, Sun YP, Li Y, et al. Hydrogen-rich saline ameliorates the severity of l-arginineinduced acute pancreatitis in rats. Biochem Biophys Res Commun 2010; 393:308-313.
19. Kajiya M, Silva MJ, Sato K, et al. Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. Biochem Biophys Res Commun 2009; 386:11-15.
20. Shen M, He J, Cai J, et al. Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning. Med Hypotheses 2010; 75:235-237.
21. Ohsawa I, Ishikawa M, Takahashi K, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 2007; 13:688-694. (Pubitemid 46889750)
22. Daba MH, Abdel-Aziz AA, Moustafa AM, et al. Effects of L-carnitine and ginkgo biloba extract (EG b 761) in experimental bleomycininduced lung fibrosis. Pharmacol Res 2002; 45:461-467. (Pubitemid 35304494)
23. Morris RG, Garrud P, Rawlins JN, et al. Place navigation impaired in rats with hippocampal lesions. Nature 1982; 297:681-683. (Pubitemid 12096189)
24. D'Hooge R, De Deyn PP: Applications of the Morris water maze in the study of learning and memory. Brain Res Brain Res Rev 2001; 36:60-90. (Pubitemid 32763130)
25. Prockop LD, Chichkova RI: Carbon monoxide intoxication: An updated review. J Neurol Sci 2007; 262:122-130. (Pubitemid 47390903)
26. Hayashida K, Sano M, Ohsawa I, et al. Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemiareperfusion injury. Biochem Biophys Res Commun 2008; 373:30-35.
27. Tapeantong T, Poungvarin N: Delayed encephalopathy and cognitive sequelae after acute carbon monoxide poisoning: report of a case and review of the literature. J Med Assoc Thai 2009; 92:1374-1379.
28. Wu DC, Jackson-Lewis V, Vila M, et al. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 2002; 22:1763-1771. (Pubitemid 35386294)
29. Ekdahl CT, Claasen JH, Bonde S, et al. Inflammation is detrimental for neurogenesis in adult brain. Proc Natl Acad Sci USA 2003; 100:13632-13637. (Pubitemid 37444791)
30. Nakao A, Toyoda Y, Sharma P, et al. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr 2010; 46:140-149.
31. Nakayama M, Nakano H, Hamada H, et al: A novel bioactive haemodialysis system using dissolved dihydrogen (H2) produced by water electrolysis: A clinical trial. Nephrol Dial Transplant 2010; 25:3026-3033